diff --git a/README.md b/README.md
index 8be7d6717e287672666b0101992a9944ca2532c2..b808846dc6169e9ae6e4ab6d3cdeb46e3a1af70f 100644
--- a/README.md
+++ b/README.md
@@ -30,6 +30,21 @@ On MacOS X:
   ```bash
   conda create -n paqr_kapac -c bioconda -c ostrokach --file requirements_py3.txt
   ```
+**Important Update**: Please not that we experienced some difficulties with some anaconda-packages which have been removed from anaconda cloud. In order to create the python3 environment please follow these steps:
+  ```bash
+  conda create -n paqr_kapac -c bioconda -c ostrokach -c r -c defaults --file requirements_py3_UPDATED.txt
+  ```
+This will result in an environment without the R package "optparse". In order to install this package please run:
+  ```bash
+  conda activate paqr_kapac
+  R
+  ```
+Now, you should find your console to be in an active R session. Here, execute:
+  ```R
+  install.packages("optparse")
+  q()
+  ```
+  
 If you already have a conda version with python2 installed, create the new python 3 environment like this:
   ```bash
   conda create -n paqr_kapac -c bioconda -c ostrokach --file requirements_py3.txt python=3
diff --git a/requirements_py3_UPDATED.txt b/requirements_py3_UPDATED.txt
new file mode 100644
index 0000000000000000000000000000000000000000..9e46dac96606db53910446731146fcd5891730a1
--- /dev/null
+++ b/requirements_py3_UPDATED.txt
@@ -0,0 +1,11 @@
+# This file may be used to create an environment using:
+# $ conda create --name tutorial --file <this file>
+python=3.5.4
+snakemake=3.13.0
+graphviz=2.38.0
+star=2.5.2a
+samtools=1.3.1
+bedtools=2.26.0
+gzip=1.7
+r-base=3.5.1
+sra-tools=2.8.2