Preprocessing remove polyAs from reads
Should we trim polyAs only from the 3 end? Should we trim polyTs from 5 prime if the read is antisense? Should we trim both polyAs from 3end and polyTs from 5end if directionality is random?
Should we trim polyAs only from the 3 end? Should we trim polyTs from 5 prime if the read is antisense? Should we trim both polyAs from 3end and polyTs from 5end if directionality is random?