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Apr 17, 2020
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Alex Kanitz
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size of the input that needs to be provided
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type: Accessions - repositories / Fastq files
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automated inferences: type of sample preparation, adaptors
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custom genomes and annotations possible?
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Output
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sample quality metrics
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complexity
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inference
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novel isoforms: splicing/polyadenylation
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SNPs/mutations
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Number/type of supported platforms
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Desktop application/needs cluster
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Workflow engine
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Modern (CWL, WDL, Snakemake, Galaxy, Nextflow)
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Legacy (anything else that's not homegrown)
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Custom
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User interface
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Browser app
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Desktop app
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Mobile app
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Command line interface (programmable)
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HTTP/"REST" API available (programmable)
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Supported platforms
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Cloud (AWS, GCP, Azure, ...)
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Kubernetes / OpenShift
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HPC (Slurm, SGE/OGE/UGA, ...)
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Desktop/laptop
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Installation
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Type
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VM
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Containerized
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Virtual env cross-language (conda)
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Virtual env single language (e.g., virtualenv)
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Package manager without virtualization (e.g., pip, Bioconductor)
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Manual install
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Instructions & auxiliary scripts available for supported platforms
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Openness
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License
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Open source development encouraged?
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Contribution instructions available?
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Contact options
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Issue tracker
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Q/A forum (e.g., Biostars)
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Chat (e.g., Slack or Gitter channel)
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Email
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Maintenance
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Actively developed?
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number of contributors
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last update
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frequency of commits
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Tests available
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Test code coverage published?
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Usability
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Clean, well-documented, programmable, easy-to-use, intuitive API for input and outputs?
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Workflow can be started quickly for one sample (incl. preparation of configs)
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Workflow can be started quickly for multiple samples (incl. preparation of configs)
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Supports local data
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Supports uploading data
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Supports cloud data (e.g., Amazon S3)
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Interfacing with SRA and/or other relevant data repos
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Interfacing with Ensembl and/or other genome resource repos
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Tooling available to filter genome resources or compile custom ones?