README.md

 # _MIRFLOWZ_
 
-Suite of [Snakemake][snakemake] workflows for the mapping and quantification
+[Snakemake][snakemake] workflow for the mapping and quantification
 of smallRNA-seq libraries, including miRNA and isomiR quantification.
 
 ## Installation
 
-All workflows live inside this repository and will be available for you to run
+The whole workflow live inside this repository and will be available for you to run
 after following the installation instructions layed out in this section.
 
 ### Cloning the repository
@@ -20,9 +20,9 @@ cd mirflowz
 
 ### Dependencies
 
-For improved reproducibility and reusability of the workflows, as well as an
+For improved reproducibility and reusability of the workflow, as well as an
 easy means to run them on a high performance computing (HPC) cluster managed,
-e.g., by [Slurm][slurm], all steps of the workflows run inside their own
+e.g., by [Slurm][slurm], all steps of the workflow run inside their own
 containers. As a consequence, running this workflow has very few individual
 dependencies. It does, however, require the package manager [Conda][conda] and
 the container engine [Singularity][singularity] to be installed before you
@@ -36,7 +36,7 @@ proceed.
 ### Setting up a virtual environment
 
 It you do not already have [Conda][conda] installed globally on your system,
-we recommend that you install [Miniconda][miniconda]. For faster creation of
+we recommend that you install [Miniconda][miniconda-installation]. For faster creation of
 the environment (and Conda environments in general), you can also install
 [Mamba][mamba] on top of Conda. In that case, replace `conda` with `mamba` in
 the commands below (particularly in `conda env create`).
@@ -55,7 +55,7 @@ the instructions in this section to make sure the workflows are ready to use.
 
 #### Run test workflows on local machine
 
-Execute the following command to run the test workflows on your local machine:
+Execute the following command to run the test workflow on your local machine:
 
 ```bash
 bash test/test_workflow_local.sh
@@ -63,7 +63,7 @@ bash test/test_workflow_local.sh
 
 #### Run test workflows via Slurm
 
-Execute the following command to run the test workflows on a Slurm-managed
+Execute the following command to run the test workflow on a Slurm-managed
 high-performance computing (HPC) cluster:
 
 ```bash
@@ -72,12 +72,12 @@ bash test/test_workflow_slurm.sh
 
 > **NOTE:** The Slurm tests were configured to run on the developer's cluster.
 > Several files may need to be modified if you would like to run tests (and
-> the actual workflows) on other systems. These may possibly include the
+> the actual workflow) on other systems. These may possibly include the
 > following (relative to the repository root directory), but potentially others
 > as well:
 >  
 > * `jobscript.sh`
-> * `RUNS/JOB/{prepare,map,quantify}/cluster.json`
+> * `test/cluster.json`
 > * `test/test_workflow_slurm.sh`
 >  
 > Consult the manual of
@@ -86,8 +86,8 @@ bash test/test_workflow_slurm.sh
 
 #### DAG and rule graph
 
-Execute the following commands to generate DAG and rule graph images for each
-workflow. Outputs will be found in the `images/` directory in the repository
+Execute the following commands to generate DAG and rule graph images for the
+workflow. The output will be found in the `images/` directory in the repository
 root.
 
 > **NOTE:** It is essential that you run the DAG and rule graph tests only
@@ -110,86 +110,122 @@ bash test/test_cleanup.sh
 
 ## Usage
 
-Now that your virtual environment is set up and the workflows are deployed and
-tested, you can go ahead and run the workflows on your samples.
+Now that your virtual environment is set up and the workflow is deployed and
+tested, you can go ahead and run the workflow on your samples.
 
-But first, here is a brief description of what each of the three workflows
-does:
+But first, here is a brief description of what the workflow does:
 
 ### Workflow description
 
-The repository contains the following workflows, all implemented in Snakemake
-and fully containerized:
+The workflow consist on one main `Snakefile` 
+gathering three different subworkflows,
+**_PREPARE_**, **_MAP_** and **_QUANTIFY_**. 
+Each one of them is implemented in an individual Snakemake file
+and fully containerized.    
+
 
 #### _PREPARE_
 
-The first workflow, **_PREPARE_** downloads and processes "genome resources"
+The first subworkflow, **_PREPARE_**, downloads and processes "genome resources"
 from the publicly available repositories [Ensembl][ensembl] and
 [miRBase][mirbase] according to your instructions. Resources are then processed
 to prepare indexes and other contingent resources that will be used in later
 steps.
 
-The scheme below is a visual representation of an example run of the
-**_PREPARE_** workflow:
-
-> ![rule-graph-prepare][rule-graph-prepare]
-
 #### _MAP_
 
-The second workflow, **_MAP_** aligns the user-provided short read smallRNA-seq
-libraries against the references generated with the **_PREPARE_** workflow. For
+The second subworkflow, **_MAP_**, aligns the user-provided short read smallRNA-seq
+libraries against the references generated with the **_PREPARE_** subworkflow. For
 increased fidelity it uses two separate aligning tools, [Segemehl][segemehl]
 and our in-house tool [Oligomap][oligomap]. In both cases, reads are aligned
 separately to the genome and the transcriptome. Afterwards, alignments are
 merged in a way that only the best alignment (or alignments) of each read are
 kept.
 
-The scheme below is a visual representation of an example run of the **_MAP_**
-workflow:
-
-> ![rule-graph-map][rule-graph-map]
-
 #### _QUANTIFY_
 
-The third and final workflow, **_QUANTIFY_** quantifies miRNA expression by
-intersecting the alignments from the **_MAP_** workflow with the annotations
-generated in the **_PREPARE_** workflow. Intersections are computed with
+The third and final subworkflow, **_QUANTIFY_**, quantifies miRNA expression by
+intersecting the alignments from the **_MAP_** subworkflow with the annotations
+generated in the **_PREPARE_** subworkflow. Intersections are computed with
 [`bedtools`][bedtools] for one or multiple of mature, primary transcripts and
 isomiRs. Reads consistent with each miRNA are counted and tabulated.
 
-The scheme below is a visual representation of an example run of the
-**_QUANTIFY_** workflow:
 
-> ![rule-graph-quantify][rule-graph-quantify]
+The schema below is a visual representation of
+an example run of the whole workflow:
+
+> ![rule-graph][rule-graph]
 
-### Running the workflows
 
-Assuming that you are currently inside the repository's root directory, change
-to the run root directory:
+### Running the workflow
+
+Assuming that you are currently inside the repository's root directory, 
+create a directory from which you will run your workflow and
+name it whatever you want e.g., `MY_ANALYSIS` and 
+head to it.
 
 ```bash
-cd RUNS
+mkdir MY_ANALYSIS
+cd MY_ANALYSIS
 ```
+Now within the `MY_ANALYSIS/` directory, 
+create a new directory to store you library; 
+name it as you like, e.g. `my_lib` and move there.    
 
-Now make a clean copy of the `JOB` directory and name it whatever you want,
-e.g., `MY_ANALYSIS`:
+```bash
+mkdir my_lib
+cd my_lib
+```
+Place your library file here. 
+In addition, create a sample table. 
+Fill it with the correct entries. 
+You can look at the `test/test_files/sample_table.csv` 
+to get an idea of what this file must contain.
 
 ```bash
-cp -r JOB MY_ANALYSIS
+touch sample_table.csv
 ```
 
-Now traverse to the new directory. You will see that there are three
-subdirectories, one for each workflow, change into the one you would like to
-run (probably `prepare`).
+Now traverse back to the previous directory.
+Here, a coupleof things must be done:  
+
+First of all, copy the `config_template.yaml` to this directory.
 
 ```bash
-cd MY_ANALYSIS
-cd {prepare,map,quantify}
+cp ..config/config_template.yaml ./config.yaml
+```
+Then, using your editor of choice, adjust the parameters of the `config.yaml`.
+The file explains what each of the parameters means and how you can meaningfully
+fill them in.  
+
+
+Accordingly to how you want
+to run the workflow you can either 
+copy the script to run it **locally** with
+
+```bash
+cp ../test/test_workflow_local.sh ./run_workflow_local.sh
+```
+or copy the script to run the workflow 
+on a **cluster via Slurm** 
+along with the `cluster.json` file with
+
+```bash
+cp ../test/test_workflow_slurm.sh ./run_workflow_slurm.sh
+cp ../test/cluster.json ./cluster.json
+```
+
+In both cases, the final 9 lines must be removed; this can be done with:
+
+```bash
+head -n 9 run_workflow_*.sh
 ```
+Finally, you can optionally copy the script 
+to remove all artifacts generated by the run:
 
-Before running the workflow adjust the parameters in file `config.yaml`. The
-file explains what each of the parameters means and how you can meaningfully
-fill them in.
+```bash
+cp ../test/test_cleanup.sh ./run_cleanup.sh
+```
 
 To start workflow execution, run:
 
@@ -207,149 +243,116 @@ To start workflow execution, run:
 After successful execution of the workflow, results and logs will be found in
 `results/` and `logs/` directories, respectively.
 
-### Appendix: Configuration files
+### Appendix: Configuration file
 
-_MIRFLOWZ_ comes with template configuration files for each individual
-workflow. These contain notes on how to fill in each parameter.
-
-#### _PREPARE_
+_MIRFLOWZ_ comes with a template configuration file 
+for the whole workflow. 
+This template contains notes on how to fill in each parameter.
 
-**File location:** `RUNS/JOB/prepare/config.yaml`
+**File location:** `config/config_template.yaml`
 
 ```yaml
 ---
-#### GLOBAL PARAMETERS #####
-
-# Directories
-# Usually there is no need to change these
-scripts_dir: "../../../scripts"
-output_dir: "results"
-local_log: "logs/local"
-cluster_log: "logs/cluster"
-
-# Isomirs annotation file
-# Number of base pairs to add/substract from 5' (start) and 3' (end) coordinates.
-bp_5p: [0] # array of numbers, e.g., [-2,-1,0,+1], to include 2 upstream and 1 downstream nts
-bp_3p: [0] # array of numbers, e.g., [-2,-1,0,+1], to include 2 upstream and 1 downstream nts
-
-# List of inputs
-organism: ["org/pre"] # e.g., ["homo_sapiens/GRCh38.100", "mus_musculus/GRCm37.98"]
-
-#### PARAMETERS SPECIFIC TO INPUTS ####
-
-org/pre: # One section for each list item in "organism"; names have to match precisely
-  # URLs to genome, gene & miRNA annotations
-  genome_url: # FTP/HTTP URL to gzipped genome in FASTA format, Ensembl style
-  gtf_url: # FTP/HTTP URL to gzipped gene annotations in GTF format, Ensembl style
-  mirna_url: # FTP/HTTP URL to unzipped microRNA annotations in GFF format, miRBase style
-
-  # Chromosome name mappings between UCSC <-> Ensembl
-  # Other organisms available at: https://github.com/dpryan79/ChromosomeMappings
-  map_chr_url: # FTP/HTTP URL to mapping table
-  # Chromosome name mapping parameters:
-  column: 1 # Column number from input file where to change chromosome name
-  delimiter: "TAB" # Delimiter of the input file
-...
-```
+#############################
+#### REQUIRED PARAMETERS ####
+#############################
 
-> **Note:** We expect the genome and gene annotations to be formatted according
-> the style used by Ensembl. Other formats are very likely to lead to problems,
-> if not in this pipeline, then further down the road in the mapping or
-> annotation pipelines. The miRNA annotation file is expected to originate from
-> miRBase, or follow their exact layout.
+# All paths are relative to the current working directory unless noted otherwise
 
-#### _MAP_
+samples: path/to/samples_table.csv 
 
-**File location:** `RUNS/JOB/map/config.yaml`
+#### GENOME RESOURCES #####
 
-```yaml
----
-#### GLOBAL PARAMETERS ####
-
-# Directories
-# Usually there is no need to change these
-scripts_dir: "../../../scripts"
-output_dir: "results"
-local_log: "logs/local"
-cluster_log: "logs/cluster"
-
-# Resources: genome, transcriptome, genes, miRs
-# All of these are produced by the "prepare" workflow
-genome: "path/to/genome.processed.fa"
-gtf: "path/to/gene_annotations.filtered.gtf"
-transcriptome: "path/to/transcriptome_idtrim.fa"
-transcriptome_index_segemehl: "path/to/transcriptome_index_segemehl.idx"
-genome_index_segemehl: "path/to/genome_index_segemehl.idx"
-exons: "path/to/exons.bed"
-header_of_collapsed_fasta: "path/to/headerOfCollapsedFasta.sam"
-
-# Tool parameters: quality filter
-q_value: 10  # Q (Phred) score; minimum quality score to keep
-p_value: 50  # minimum % of bases that must have Q quality
+# All genome resources have to match the source/organism
+# of all samples in the sample table
 
-# Tool parameters: adapter removal
-error_rate: 0.1  # fraction of allowed errors
-minimum_length: 15  # discard processed reads shorter than the indicated length
-overlap: 3  # minimum overlap length of adapter and read to trim the bases
-max_n: 0  # discard reads containing more than the indicated number of N bases
+# FTP/HTTP URL to gzipped genome in FASTA format, Ensembl style
+genome_url: # e.g. "ftp://ftp.ensembl.org/pub/release-106/fasta/homo_sapiens/dna/Homo_sapiens.GRCh38.dna_sm.primary_assembly.fa.gz"
 
-# Tool parameters: mapping
-max_length_reads: 30  # maximum length of processed reads to map with oligomap
-nh: 100  # discard reads with more mappings than the indicated number
+# FTP/HTTP URL to gzipped gene annotations in GTF format, Ensembl style
+gtf_url: # e.g. "ftp://ftp.ensembl.org/pub/release-106/gtf/homo_sapiens/Homo_sapiens.GRCh38.106.chr.gtf.gz"
 
-# Inputs information
-input_dir: "path/to/input_directory"
-sample: ["sample_1", "sample_2"]  # put all sample names, separated by comma
+# FTP/HTTP URL to unzipped microRNA annotations in GFF format, miRBase style
+mirna_url: # e.g. "https://www.mirbase.org/ftp/CURRENT/genomes/hsa.gff3"
 
-#### PARAMETERS SPECIFIC TO INPUTS ####
+# Tab-separated mappings table between UCSC (column 1)
+# and Ensembl (coulm 2) chromosome names 
+# Available at: https://github.com/dpryan79/ChromosomeMappings
+map_chr_url: # e.g. "https://raw.githubusercontent.com/dpryan79/ChromosomeMappings/master/GRCh38_UCSC2ensembl.txt"
 
-sample_1:  # one section per list item in "sample"; names have to match
-    adapter: "XXXXXXXXXXXXXXXXXXXX"  # 3' adapter sequence to trim
-    format: "fa"  # file format; currently supported: "fa"
-...
-```
 
-#### _QUANTIFY_
+###############################
+#### "OPTIONAL" PARAMETERS ####
+###############################
 
-**File location:** `RUNS/JOB/quantify/config.yaml`
+# The below parameters only need to be changed if the default behavior of
+# MIRFLOWZ is to be changed; however, they still need to be present!
 
-```yaml
----
-#### GLOBAL PARAMETERS ####
+#### DIRECTORIES ####
+
+output_dir: results/
+local_log: logs/local/
+cluster_log: logs/cluster/
+scripts_dir: ../scripts/
+
+
+#### ISOMIR GENERATION PARAMETERS ####
+
+# Generate isomiR annotations with the indicated number of shifts relative to
+# the start and end position of each annotated mature miRNA, as an array of
+# relative positions
+# Examples:
+# - `bp_5p: [-2,0,+1]` and `bp_3p: [+1]` generates 3 isomiRs for each mature
+#   miRNA: one that starts two nucleotides before, one that starts exactly at
+#   and one that starts one nucleotide after the annotated mature miRNA; all
+#   isomiRs will stop one nucleotide after the end of the annotated mature
+#   miRNA; note that because `0` is not included in the `bp_3p` array, the
+#   annotated mature miRNAs will not be included in this example
+# - Use `bp_5p: [0]` and `bp_3p: [0]` to only include the mature annotated
+#   miRNAs and no isomiRs
 
-# Directories
-# Usually there is no need to change these
-output_dir: "results"
-scripts_dir: "../scripts"
-local_log: "logs/local"
-cluster_log: "logs/cluster"
+bp_5p: [-2, -1, 0, +1, +2]
+bp_3p: [-2, -1, 0, +1, +2]
+
+#### PROCESSING PARAMETERS #### 
+
+# quality filter
+q_value: 10  # Q (Phred) score; minimum quality score to keep
+p_value: 50  # minimum % of bases that must have Q quality
+
+# adapter removal
+error_rate: 0.1     # fraction of allowed errors
+minimum_length: 15  # discard processed reads shorter than the indicated length
+overlap: 3          # minimum overlap length of adapter and read to trim the bases
+max_n: 0            # discard reads containing more than the indicated number of N bases
+
+# mapping
+max_length_reads: 30  # maximum length of processed reads to map with oligomap
+nh: 100               # discard reads with more mappings than the indicated number
+
+#### QUANTIFICATION PARAMETERS ####
 
 # Types of miRNAs to quantify
 # Remove miRNA types you are not interested in
 mir_list: ["miRNA", "miRNA_primary_transcript", "isomirs"]
-
-# Resources: miR annotations, chromosome name mappings
-# All of these are produced by the "prepare" workflow
-mirnas_anno: "path/to/mirna_filtered.bed"
-isomirs_anno: "path/to/isomirs_annotation.bed"
-
-# Inputs information
-input_dir: "path/to/input_directory"
-sample: ["sample_1", "sample_2"]  # put all samples, separated by comma
 ...
 ```
 
+> **Note:** We expect the genome and gene annotations to be formatted according
+> the style used by Ensembl. Other formats are very likely to lead to problems.
+> The miRNA annotation file is expected to originate from
+> miRBase, or follow their exact layout.
+
+
 [bedtools]: <https://github.com/arq5x/bedtools2>
 [conda]: <https://docs.conda.io/projects/conda/en/latest/index.html>
-[cluster execution]: <https://snakemake.readthedocs.io/en/stable/executing/cluster-cloud.html#cluster-execution>
+[cluster execution]: <https://snakemake.readthedocs.io/en/stable/executing/cluster.html>
 [ensembl]: <https://ensembl.org/>
 [mamba]: <https://github.com/mamba-org/mamba>
 [miniconda-installation]: <https://docs.conda.io/en/latest/miniconda.html>
 [mirbase]: <https://mirbase.org/>
 [oligomap]: <https://bio.tools/oligomap>
-[rule-graph-map]: images/rule_graph_map.svg
-[rule-graph-prepare]: images/rule_graph_prepare.svg
-[rule-graph-quantify]: images/rule_graph_quantify.svg
+[rule-graph]: images/rule_graph.svg
 [segemehl]: <https://www.bioinf.uni-leipzig.de/Software/segemehl/>
 [singularity]: <https://sylabs.io/singularity/>
 [slurm]: <https://slurm.schedmd.com/documentation.html>

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+<text text-anchor="middle" x="655" y="-1383.5" font-family="sans" font-size="10.00" fill="#000000">mapping_transcriptome_oligomap</text>
+</g>
+<!-- 2&#45;&gt;40 -->
+<g id="edge56" class="edge">
+<title>2&#45;&gt;40</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M799.1277,-1444.9613C773.921,-1434.6495 738.1695,-1420.0239 708.5807,-1407.9194"/>
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+<!-- 3 -->
+<g id="node4" class="node">
+<title>3</title>
+<path fill="none" stroke="#d85656" stroke-width="2" d="M892,-1548C892,-1548 770,-1548 770,-1548 764,-1548 758,-1542 758,-1536 758,-1536 758,-1524 758,-1524 758,-1518 764,-1512 770,-1512 770,-1512 892,-1512 892,-1512 898,-1512 904,-1518 904,-1524 904,-1524 904,-1536 904,-1536 904,-1542 898,-1548 892,-1548"/>
+<text text-anchor="middle" x="831" y="-1527.5" font-family="sans" font-size="10.00" fill="#000000">extract_transcriptome_seqs</text>
+</g>
+<!-- 3&#45;&gt;2 -->
+<g id="edge10" class="edge">
+<title>3&#45;&gt;2</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M831,-1511.8314C831,-1504.131 831,-1494.9743 831,-1486.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="834.5001,-1486.4132 831,-1476.4133 827.5001,-1486.4133 834.5001,-1486.4132"/>
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+<!-- 4 -->
+<g id="node5" class="node">
+<title>4</title>
+<path fill="none" stroke="#9fd856" stroke-width="2" d="M341,-1620C341,-1620 269,-1620 269,-1620 263,-1620 257,-1614 257,-1608 257,-1608 257,-1596 257,-1596 257,-1590 263,-1584 269,-1584 269,-1584 341,-1584 341,-1584 347,-1584 353,-1590 353,-1596 353,-1596 353,-1608 353,-1608 353,-1614 347,-1620 341,-1620"/>
+<text text-anchor="middle" x="305" y="-1599.5" font-family="sans" font-size="10.00" fill="#000000">genome_process</text>
+</g>
+<!-- 4&#45;&gt;3 -->
+<g id="edge11" class="edge">
+<title>4&#45;&gt;3</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M353.1613,-1595.4651C427.7113,-1585.3422 575.5489,-1565.2385 701,-1548 716.0911,-1545.9263 732.1661,-1543.7081 747.682,-1541.5623"/>
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+</g>
+<!-- 6 -->
+<g id="node7" class="node">
+<title>6</title>
+<path fill="none" stroke="#d85e56" stroke-width="2" d="M570,-1548C570,-1548 410,-1548 410,-1548 404,-1548 398,-1542 398,-1536 398,-1536 398,-1524 398,-1524 398,-1518 404,-1512 410,-1512 410,-1512 570,-1512 570,-1512 576,-1512 582,-1518 582,-1524 582,-1524 582,-1536 582,-1536 582,-1542 576,-1548 570,-1548"/>
+<text text-anchor="middle" x="490" y="-1527.5" font-family="sans" font-size="10.00" fill="#000000">generate_segemehl_index_genome</text>
+</g>
+<!-- 4&#45;&gt;6 -->
+<g id="edge13" class="edge">
+<title>4&#45;&gt;6</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M351.6833,-1583.8314C376.7559,-1574.0734 407.8367,-1561.977 434.1809,-1551.7242"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="435.6027,-1554.9266 443.6524,-1548.038 433.0638,-1548.4033 435.6027,-1554.9266"/>
+</g>
+<!-- 9 -->
+<g id="node10" class="node">
+<title>9</title>
+<path fill="none" stroke="#56d87b" stroke-width="2" d="M196,-900C196,-900 92,-900 92,-900 86,-900 80,-894 80,-888 80,-888 80,-876 80,-876 80,-870 86,-864 92,-864 92,-864 196,-864 196,-864 202,-864 208,-870 208,-876 208,-876 208,-888 208,-888 208,-894 202,-900 196,-900"/>
+<text text-anchor="middle" x="144" y="-879.5" font-family="sans" font-size="10.00" fill="#000000">create_header_genome</text>
+</g>
+<!-- 4&#45;&gt;9 -->
+<g id="edge16" class="edge">
+<title>4&#45;&gt;9</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M256.829,-1590.616C217.1776,-1580.2861 165.2578,-1564.2301 151,-1548 124.0187,-1517.2865 132,-1498.8816 132,-1458 132,-1458 132,-1458 132,-1026 132,-985.7369 136.7166,-939.3594 140.2358,-910.3596"/>
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+</g>
+<!-- 13 -->
+<g id="node14" class="node">
+<title>13</title>
+<path fill="none" stroke="#56d882" stroke-width="2" d="M219.5,-1548C219.5,-1548 172.5,-1548 172.5,-1548 166.5,-1548 160.5,-1542 160.5,-1536 160.5,-1536 160.5,-1524 160.5,-1524 160.5,-1518 166.5,-1512 172.5,-1512 172.5,-1512 219.5,-1512 219.5,-1512 225.5,-1512 231.5,-1518 231.5,-1524 231.5,-1524 231.5,-1536 231.5,-1536 231.5,-1542 225.5,-1548 219.5,-1548"/>
+<text text-anchor="middle" x="196" y="-1527.5" font-family="sans" font-size="10.00" fill="#000000">mirna_anno</text>
+</g>
+<!-- 4&#45;&gt;13 -->
+<g id="edge21" class="edge">
+<title>4&#45;&gt;13</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M277.4947,-1583.8314C263.682,-1574.7074 246.7744,-1563.539 231.9471,-1553.7449"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="233.7696,-1550.7541 223.4965,-1548.1628 229.9114,-1556.5949 233.7696,-1550.7541"/>
+</g>
+<!-- 14 -->
+<g id="node15" class="node">
+<title>14</title>
+<path fill="none" stroke="#c6d856" stroke-width="2" d="M292,-1548C292,-1548 262,-1548 262,-1548 256,-1548 250,-1542 250,-1536 250,-1536 250,-1524 250,-1524 250,-1518 256,-1512 262,-1512 262,-1512 292,-1512 292,-1512 298,-1512 304,-1518 304,-1524 304,-1524 304,-1536 304,-1536 304,-1542 298,-1548 292,-1548"/>
+<text text-anchor="middle" x="277" y="-1527.5" font-family="sans" font-size="10.00" fill="#000000">dict_chr</text>
+</g>
+<!-- 4&#45;&gt;14 -->
+<g id="edge22" class="edge">
+<title>4&#45;&gt;14</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M297.9344,-1583.8314C294.874,-1575.9617 291.2221,-1566.5712 287.8318,-1557.8533"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="291.0473,-1556.4647 284.1607,-1548.4133 284.5232,-1559.0019 291.0473,-1556.4647"/>
+</g>
+<!-- 21 -->
+<g id="node22" class="node">
+<title>21</title>
+<path fill="none" stroke="#56d88a" stroke-width="2" d="M92,-1260C92,-1260 12,-1260 12,-1260 6,-1260 0,-1254 0,-1248 0,-1248 0,-1236 0,-1236 0,-1230 6,-1224 12,-1224 12,-1224 92,-1224 92,-1224 98,-1224 104,-1230 104,-1236 104,-1236 104,-1248 104,-1248 104,-1254 98,-1260 92,-1260"/>
+<text text-anchor="middle" x="52" y="-1239.5" font-family="sans" font-size="10.00" fill="#000000">create_index_fasta</text>
+</g>
+<!-- 4&#45;&gt;21 -->
+<g id="edge30" class="edge">
+<title>4&#45;&gt;21</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M256.8314,-1592.6806C208.7623,-1582.5881 139.1027,-1565.5641 118,-1548 83.6269,-1519.3908 73,-1502.7214 73,-1458 73,-1458 73,-1458 73,-1386 73,-1345.2729 64.673,-1298.7384 58.5061,-1269.8595"/>
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+</g>
+<!-- 46 -->
+<g id="node47" class="node">
+<title>46</title>
+<path fill="none" stroke="#d86656" stroke-width="2" d="M499.5,-1476C499.5,-1476 372.5,-1476 372.5,-1476 366.5,-1476 360.5,-1470 360.5,-1464 360.5,-1464 360.5,-1452 360.5,-1452 360.5,-1446 366.5,-1440 372.5,-1440 372.5,-1440 499.5,-1440 499.5,-1440 505.5,-1440 511.5,-1446 511.5,-1452 511.5,-1452 511.5,-1464 511.5,-1464 511.5,-1470 505.5,-1476 499.5,-1476"/>
+<text text-anchor="middle" x="436" y="-1455.5" font-family="sans" font-size="10.00" fill="#000000">mapping_genome_segemehl</text>
+</g>
+<!-- 4&#45;&gt;46 -->
+<g id="edge65" class="edge">
+<title>4&#45;&gt;46</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M321.5912,-1583.7623C344.6242,-1558.4436 386.4036,-1512.5182 412.5973,-1483.7251"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="415.4031,-1485.842 419.5435,-1476.0896 410.2252,-1481.1315 415.4031,-1485.842"/>
+</g>
+<!-- 48 -->
+<g id="node49" class="node">
+<title>48</title>
+<path fill="none" stroke="#59d856" stroke-width="2" d="M491,-1404C491,-1404 367,-1404 367,-1404 361,-1404 355,-1398 355,-1392 355,-1392 355,-1380 355,-1380 355,-1374 361,-1368 367,-1368 367,-1368 491,-1368 491,-1368 497,-1368 503,-1374 503,-1380 503,-1380 503,-1392 503,-1392 503,-1398 497,-1404 491,-1404"/>
+<text text-anchor="middle" x="429" y="-1383.5" font-family="sans" font-size="10.00" fill="#000000">mapping_genome_oligomap</text>
+</g>
+<!-- 4&#45;&gt;48 -->
+<g id="edge69" class="edge">
+<title>4&#45;&gt;48</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M308.665,-1583.8908C316.4337,-1546.7481 335.2213,-1463.4635 352,-1440 360.4831,-1428.1371 372.4203,-1417.9785 384.3686,-1409.7791"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="386.5418,-1412.541 393.0214,-1404.1586 382.7287,-1406.6707 386.5418,-1412.541"/>
+</g>
+<!-- 5 -->
+<g id="node6" class="node">
+<title>5</title>
+<path fill="none" stroke="#56d86b" stroke-width="2" d="M984.5,-1620C984.5,-1620 923.5,-1620 923.5,-1620 917.5,-1620 911.5,-1614 911.5,-1608 911.5,-1608 911.5,-1596 911.5,-1596 911.5,-1590 917.5,-1584 923.5,-1584 923.5,-1584 984.5,-1584 984.5,-1584 990.5,-1584 996.5,-1590 996.5,-1596 996.5,-1596 996.5,-1608 996.5,-1608 996.5,-1614 990.5,-1620 984.5,-1620"/>
+<text text-anchor="middle" x="954" y="-1599.5" font-family="sans" font-size="10.00" fill="#000000">filter_anno_gtf</text>
+</g>
+<!-- 5&#45;&gt;3 -->
+<g id="edge12" class="edge">
+<title>5&#45;&gt;3</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M922.9619,-1583.8314C907.2295,-1574.6221 887.9389,-1563.3301 871.0956,-1553.4706"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="872.4265,-1550.1941 862.0282,-1548.1628 868.8902,-1556.2352 872.4265,-1550.1941"/>
+</g>
+<!-- 8 -->
+<g id="node9" class="node">
+<title>8</title>
+<path fill="none" stroke="#d8cb56" stroke-width="2" d="M1094.5,-1188C1094.5,-1188 1035.5,-1188 1035.5,-1188 1029.5,-1188 1023.5,-1182 1023.5,-1176 1023.5,-1176 1023.5,-1164 1023.5,-1164 1023.5,-1158 1029.5,-1152 1035.5,-1152 1035.5,-1152 1094.5,-1152 1094.5,-1152 1100.5,-1152 1106.5,-1158 1106.5,-1164 1106.5,-1164 1106.5,-1176 1106.5,-1176 1106.5,-1182 1100.5,-1188 1094.5,-1188"/>
+<text text-anchor="middle" x="1065" y="-1167.5" font-family="sans" font-size="10.00" fill="#000000">get_exons_gtf</text>
+</g>
+<!-- 5&#45;&gt;8 -->
+<g id="edge15" class="edge">
+<title>5&#45;&gt;8</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M985.0381,-1583.9286C1021.4758,-1560.1156 1077,-1514.5511 1077,-1458 1077,-1458 1077,-1458 1077,-1314 1077,-1273.7369 1072.2834,-1227.3594 1068.7642,-1198.3596"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1072.2007,-1197.6332 1067.4864,-1188.145 1065.2548,-1198.5021 1072.2007,-1197.6332"/>
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+<!-- 6&#45;&gt;0 -->
+<g id="edge1" class="edge">
+<title>6&#45;&gt;0</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M502.9048,-1511.8972C509.4323,-1501.8087 516.8357,-1488.7411 521,-1476 543.5059,-1407.1416 539,-1386.4431 539,-1314 539,-1314 539,-1314 539,-162 539,-116.7853 509.5542,-71.6965 487.5632,-44.3276"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="490.0916,-41.8931 481.0187,-36.4221 484.6996,-46.357 490.0916,-41.8931"/>
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+<!-- 6&#45;&gt;46 -->
+<g id="edge63" class="edge">
+<title>6&#45;&gt;46</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M476.3735,-1511.8314C470.154,-1503.5386 462.6678,-1493.557 455.84,-1484.4533"/>
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+</g>
+<!-- 7 -->
+<g id="node8" class="node">
+<title>7</title>
+<path fill="none" stroke="#56d8c9" stroke-width="2" d="M1057,-1044C1057,-1044 1023,-1044 1023,-1044 1017,-1044 1011,-1038 1011,-1032 1011,-1032 1011,-1020 1011,-1020 1011,-1014 1017,-1008 1023,-1008 1023,-1008 1057,-1008 1057,-1008 1063,-1008 1069,-1014 1069,-1020 1069,-1020 1069,-1032 1069,-1032 1069,-1038 1063,-1044 1057,-1044"/>
+<text text-anchor="middle" x="1040" y="-1023.5" font-family="sans" font-size="10.00" fill="#000000">gtftobed</text>
+</g>
+<!-- 7&#45;&gt;0 -->
+<g id="edge8" class="edge">
+<title>7&#45;&gt;0</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1037.928,-1007.8427C1034.9989,-980.5621 1030,-927.359 1030,-882 1030,-882 1030,-882 1030,-162 1030,-119.3959 1030.6527,-98.1267 997,-72 957.9501,-41.6832 616.1215,-24.4766 501.3755,-19.5151"/>
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+</g>
+<!-- 30 -->
+<g id="node31" class="node">
+<title>30</title>
+<path fill="none" stroke="#56d8b9" stroke-width="2" d="M782.5,-972C782.5,-972 729.5,-972 729.5,-972 723.5,-972 717.5,-966 717.5,-960 717.5,-960 717.5,-948 717.5,-948 717.5,-942 723.5,-936 729.5,-936 729.5,-936 782.5,-936 782.5,-936 788.5,-936 794.5,-942 794.5,-948 794.5,-948 794.5,-960 794.5,-960 794.5,-966 788.5,-972 782.5,-972"/>
+<text text-anchor="middle" x="756" y="-951.5" font-family="sans" font-size="10.00" fill="#000000">trans_to_gen</text>
+</g>
+<!-- 7&#45;&gt;30 -->
+<g id="edge42" class="edge">
+<title>7&#45;&gt;30</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1010.9417,-1018.6331C962.2967,-1006.3006 863.8888,-981.3521 804.5761,-966.3151"/>
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+</g>
+<!-- 8&#45;&gt;7 -->
+<g id="edge14" class="edge">
+<title>8&#45;&gt;7</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1061.8337,-1151.7623C1057.5508,-1127.0928 1049.8715,-1082.8598 1044.8564,-1053.9731"/>
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+<!-- 9&#45;&gt;0 -->
+<g id="edge5" class="edge">
+<title>9&#45;&gt;0</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M132.2828,-863.7256C116.401,-837.1531 90,-785.793 90,-738 90,-738 90,-738 90,-666 90,-569.1386 61,-546.8614 61,-450 61,-450 61,-450 61,-162 61,-109.9317 90.8041,-97.8543 136,-72 185.0586,-43.936 351.0542,-27.205 426.3301,-20.8934"/>
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+</g>
+<!-- 28 -->
+<g id="node29" class="node">
+<title>28</title>
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+<text text-anchor="middle" x="403" y="-807.5" font-family="sans" font-size="10.00" fill="#000000">add_header</text>
+</g>
+<!-- 9&#45;&gt;28 -->
+<g id="edge37" class="edge">
+<title>9&#45;&gt;28</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M208.0225,-864.2022C254.2444,-851.3529 315.5688,-834.3052 357.0052,-822.7862"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="358.1324,-826.1056 366.8296,-820.0551 356.2575,-819.3614 358.1324,-826.1056"/>
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+<!-- 10 -->
+<g id="node11" class="node">
+<title>10</title>
+<path fill="none" stroke="#56d8b1" stroke-width="2" d="M274.5,-468C274.5,-468 241.5,-468 241.5,-468 235.5,-468 229.5,-462 229.5,-456 229.5,-456 229.5,-444 229.5,-444 229.5,-438 235.5,-432 241.5,-432 241.5,-432 274.5,-432 274.5,-432 280.5,-432 286.5,-438 286.5,-444 286.5,-444 286.5,-456 286.5,-456 286.5,-462 280.5,-468 274.5,-468"/>
+<text text-anchor="middle" x="258" y="-447.5" font-family="sans" font-size="10.00" fill="#000000">gfftobed</text>
+</g>
+<!-- 10&#45;&gt;0 -->
+<g id="edge7" class="edge">
+<title>10&#45;&gt;0</title>
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+<!-- 19 -->
+<g id="node20" class="node">
+<title>19</title>
+<path fill="none" stroke="#56b9d8" stroke-width="2" d="M218.5,-396C218.5,-396 139.5,-396 139.5,-396 133.5,-396 127.5,-390 127.5,-384 127.5,-384 127.5,-372 127.5,-372 127.5,-366 133.5,-360 139.5,-360 139.5,-360 218.5,-360 218.5,-360 224.5,-360 230.5,-366 230.5,-372 230.5,-372 230.5,-384 230.5,-384 230.5,-390 224.5,-396 218.5,-396"/>
+<text text-anchor="middle" x="179" y="-375.5" font-family="sans" font-size="10.00" fill="#000000">filter_mature_mirs</text>
+</g>
+<!-- 10&#45;&gt;19 -->
+<g id="edge28" class="edge">
+<title>10&#45;&gt;19</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M238.065,-431.8314C228.5217,-423.1337 216.9401,-412.5783 206.5694,-403.1265"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="208.6772,-400.3121 198.9287,-396.1628 203.962,-405.4857 208.6772,-400.3121"/>
+</g>
+<!-- 52 -->
+<g id="node53" class="node">
+<title>52</title>
+<path fill="none" stroke="#88d856" stroke-width="2" d="M386.5,-252C386.5,-252 321.5,-252 321.5,-252 315.5,-252 309.5,-246 309.5,-240 309.5,-240 309.5,-228 309.5,-228 309.5,-222 315.5,-216 321.5,-216 321.5,-216 386.5,-216 386.5,-216 392.5,-216 398.5,-222 398.5,-228 398.5,-228 398.5,-240 398.5,-240 398.5,-246 392.5,-252 386.5,-252"/>
+<text text-anchor="middle" x="354" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">intersect_mirna</text>
+</g>
+<!-- 10&#45;&gt;52 -->
+<g id="edge74" class="edge">
+<title>10&#45;&gt;52</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M264.4072,-431.6638C275.2414,-401.2571 298.4139,-338.7216 323,-288 327.363,-278.9991 332.622,-269.45 337.5593,-260.925"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="340.6686,-262.5426 342.7329,-252.1508 334.6388,-258.9872 340.6686,-262.5426"/>
+</g>
+<!-- 11 -->
+<g id="node12" class="node">
+<title>11</title>
+<path fill="none" stroke="#56d873" stroke-width="2" d="M295,-828C295,-828 221,-828 221,-828 215,-828 209,-822 209,-816 209,-816 209,-804 209,-804 209,-798 215,-792 221,-792 221,-792 295,-792 295,-792 301,-792 307,-798 307,-804 307,-804 307,-816 307,-816 307,-822 301,-828 295,-828"/>
+<text text-anchor="middle" x="258" y="-807.5" font-family="sans" font-size="10.00" fill="#000000">filter_mir_1_anno</text>
+</g>
+<!-- 11&#45;&gt;10 -->
+<g id="edge17" class="edge">
+<title>11&#45;&gt;10</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M258,-791.8146C258,-764.4983 258,-711.25 258,-666 258,-666 258,-666 258,-594 258,-553.876 258,-507.4631 258,-478.4177"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="261.5001,-478.1853 258,-468.1854 254.5001,-478.1854 261.5001,-478.1853"/>
+</g>
+<!-- 12 -->
+<g id="node13" class="node">
+<title>12</title>
+<path fill="none" stroke="#d8a456" stroke-width="2" d="M292,-1476C292,-1476 224,-1476 224,-1476 218,-1476 212,-1470 212,-1464 212,-1464 212,-1452 212,-1452 212,-1446 218,-1440 224,-1440 224,-1440 292,-1440 292,-1440 298,-1440 304,-1446 304,-1452 304,-1452 304,-1464 304,-1464 304,-1470 298,-1476 292,-1476"/>
+<text text-anchor="middle" x="258" y="-1455.5" font-family="sans" font-size="10.00" fill="#000000">map_chr_names</text>
+</g>
+<!-- 12&#45;&gt;11 -->
+<g id="edge18" class="edge">
+<title>12&#45;&gt;11</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M258,-1439.8146C258,-1412.4983 258,-1359.25 258,-1314 258,-1314 258,-1314 258,-954 258,-913.876 258,-867.4631 258,-838.4177"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="261.5001,-838.1853 258,-828.1854 254.5001,-838.1854 261.5001,-838.1853"/>
+</g>
+<!-- 13&#45;&gt;12 -->
+<g id="edge19" class="edge">
+<title>13&#45;&gt;12</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M211.6452,-1511.8314C218.8591,-1503.454 227.557,-1493.3531 235.4605,-1484.1749"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="238.2711,-1486.2748 242.1441,-1476.4133 232.9667,-1481.7071 238.2711,-1486.2748"/>
+</g>
+<!-- 14&#45;&gt;12 -->
+<g id="edge20" class="edge">
+<title>14&#45;&gt;12</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M272.2055,-1511.8314C270.1511,-1504.0463 267.704,-1494.7729 265.4244,-1486.1347"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="268.7948,-1485.1892 262.8591,-1476.4133 262.0265,-1486.9753 268.7948,-1485.1892"/>
+</g>
+<!-- 15 -->
+<g id="node16" class="node">
+<title>15</title>
+<path fill="none" stroke="#56a9d8" stroke-width="2" d="M214.5,-108C214.5,-108 157.5,-108 157.5,-108 151.5,-108 145.5,-102 145.5,-96 145.5,-96 145.5,-84 145.5,-84 145.5,-78 151.5,-72 157.5,-72 157.5,-72 214.5,-72 214.5,-72 220.5,-72 226.5,-78 226.5,-84 226.5,-84 226.5,-96 226.5,-96 226.5,-102 220.5,-108 214.5,-108"/>
+<text text-anchor="middle" x="186" y="-87.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_final</text>
+</g>
+<!-- 15&#45;&gt;0 -->
+<g id="edge3" class="edge">
+<title>15&#45;&gt;0</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M226.5405,-77.315C232.7088,-75.4769 239.012,-73.6504 245,-72 308.6092,-54.4686 383.3556,-36.6223 427.0238,-26.47"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="427.9533,-29.8474 436.9054,-24.1808 426.3734,-23.028 427.9533,-29.8474"/>
+</g>
+<!-- 16 -->
+<g id="node17" class="node">
+<title>16</title>
+<path fill="none" stroke="#d89c56" stroke-width="2" d="M217,-180C217,-180 149,-180 149,-180 143,-180 137,-174 137,-168 137,-168 137,-156 137,-156 137,-150 143,-144 149,-144 149,-144 217,-144 217,-144 223,-144 229,-150 229,-156 229,-156 229,-168 229,-168 229,-174 223,-180 217,-180"/>
+<text text-anchor="middle" x="183" y="-159.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_concat</text>
+</g>
+<!-- 16&#45;&gt;15 -->
+<g id="edge23" class="edge">
+<title>16&#45;&gt;15</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M183.757,-143.8314C184.0779,-136.131 184.4594,-126.9743 184.816,-118.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="188.3133,-118.5503 185.2328,-108.4133 181.3194,-118.2589 188.3133,-118.5503"/>
+</g>
+<!-- 17 -->
+<g id="node18" class="node">
+<title>17</title>
+<path fill="none" stroke="#d86e56" stroke-width="2" d="M218,-252C218,-252 144,-252 144,-252 138,-252 132,-246 132,-240 132,-240 132,-228 132,-228 132,-222 138,-216 144,-216 144,-216 218,-216 218,-216 224,-216 230,-222 230,-228 230,-228 230,-240 230,-240 230,-246 224,-252 218,-252"/>
+<text text-anchor="middle" x="181" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_rename</text>
+</g>
+<!-- 17&#45;&gt;16 -->
+<g id="edge24" class="edge">
+<title>17&#45;&gt;16</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M181.5047,-215.8314C181.7186,-208.131 181.9729,-198.9743 182.2106,-190.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="185.7094,-190.5066 182.4885,-180.4133 178.7121,-190.3122 185.7094,-190.5066"/>
+</g>
+<!-- 18 -->
+<g id="node19" class="node">
+<title>18</title>
+<path fill="none" stroke="#56d863" stroke-width="2" d="M195.5,-324C195.5,-324 162.5,-324 162.5,-324 156.5,-324 150.5,-318 150.5,-312 150.5,-312 150.5,-300 150.5,-300 150.5,-294 156.5,-288 162.5,-288 162.5,-288 195.5,-288 195.5,-288 201.5,-288 207.5,-294 207.5,-300 207.5,-300 207.5,-312 207.5,-312 207.5,-318 201.5,-324 195.5,-324"/>
+<text text-anchor="middle" x="179" y="-303.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno</text>
+</g>
+<!-- 18&#45;&gt;17 -->
+<g id="edge25" class="edge">
+<title>18&#45;&gt;17</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M179.5047,-287.8314C179.7186,-280.131 179.9729,-270.9743 180.2106,-262.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="183.7094,-262.5066 180.4885,-252.4133 176.7121,-262.3122 183.7094,-262.5066"/>
+</g>
+<!-- 19&#45;&gt;18 -->
+<g id="edge26" class="edge">
+<title>19&#45;&gt;18</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M179,-359.8314C179,-352.131 179,-342.9743 179,-334.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="182.5001,-334.4132 179,-324.4133 175.5001,-334.4133 182.5001,-334.4132"/>
+</g>
+<!-- 20 -->
+<g id="node21" class="node">
+<title>20</title>
+<path fill="none" stroke="#56d8d8" stroke-width="2" d="M84,-972C84,-972 20,-972 20,-972 14,-972 8,-966 8,-960 8,-960 8,-948 8,-948 8,-942 14,-936 20,-936 20,-936 84,-936 84,-936 90,-936 96,-942 96,-948 96,-948 96,-960 96,-960 96,-966 90,-972 84,-972"/>
+<text text-anchor="middle" x="52" y="-951.5" font-family="sans" font-size="10.00" fill="#000000">extract_chr_len</text>
+</g>
+<!-- 20&#45;&gt;18 -->
+<g id="edge27" class="edge">
+<title>20&#45;&gt;18</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M52,-935.8146C52,-908.4983 52,-855.25 52,-810 52,-810 52,-810 52,-666 52,-526.8726 47.749,-480.0885 118,-360 124.4722,-348.9363 134.0065,-338.9386 143.6238,-330.6386"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="146.1241,-333.1156 151.6564,-324.0798 141.6969,-327.6934 146.1241,-333.1156"/>
+</g>
+<!-- 21&#45;&gt;20 -->
+<g id="edge29" class="edge">
+<title>21&#45;&gt;20</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M52,-1223.9843C52,-1175.2939 52,-1040.7961 52,-982.0573"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="55.5001,-982.0088 52,-972.0089 48.5001,-982.0089 55.5001,-982.0088"/>
+</g>
+<!-- 22 -->
+<g id="node23" class="node">
+<title>22</title>
+<path fill="none" stroke="#d8bc56" stroke-width="2" d="M497.5,-324C497.5,-324 454.5,-324 454.5,-324 448.5,-324 442.5,-318 442.5,-312 442.5,-312 442.5,-300 442.5,-300 442.5,-294 448.5,-288 454.5,-288 454.5,-288 497.5,-288 497.5,-288 503.5,-288 509.5,-294 509.5,-300 509.5,-300 509.5,-312 509.5,-312 509.5,-318 503.5,-324 497.5,-324"/>
+<text text-anchor="middle" x="476" y="-303.5" font-family="sans" font-size="10.00" fill="#000000">index_bam</text>
+</g>
+<!-- 22&#45;&gt;0 -->
+<g id="edge6" class="edge">
+<title>22&#45;&gt;0</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M477.8348,-287.9537C481.4459,-248.5016 488.1229,-151.7242 476,-72 474.7209,-63.5884 472.89,-54.5316 471.0423,-46.2835"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="474.4122,-45.3222 468.7333,-36.3778 467.5949,-46.9113 474.4122,-45.3222"/>
+</g>
+<!-- 23 -->
+<g id="node24" class="node">
+<title>23</title>
+<path fill="none" stroke="#565bd8" stroke-width="2" d="M437,-468C437,-468 369,-468 369,-468 363,-468 357,-462 357,-456 357,-456 357,-444 357,-444 357,-438 363,-432 369,-432 369,-432 437,-432 437,-432 443,-432 449,-438 449,-444 449,-444 449,-456 449,-456 449,-462 443,-468 437,-468"/>
+<text text-anchor="middle" x="403" y="-447.5" font-family="sans" font-size="10.00" fill="#000000">sort_by_position</text>
+</g>
+<!-- 23&#45;&gt;22 -->
+<g id="edge31" class="edge">
+<title>23&#45;&gt;22</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M412.2455,-431.7623C424.8612,-406.8764 447.5694,-362.0822 462.2028,-333.2165"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="465.4297,-334.5916 466.8296,-324.0896 459.1861,-331.4264 465.4297,-334.5916"/>
+</g>
+<!-- 54 -->
+<g id="node55" class="node">
+<title>54</title>
+<path fill="none" stroke="#56c9d8" stroke-width="2" d="M401.5,-396C401.5,-396 360.5,-396 360.5,-396 354.5,-396 348.5,-390 348.5,-384 348.5,-384 348.5,-372 348.5,-372 348.5,-366 354.5,-360 360.5,-360 360.5,-360 401.5,-360 401.5,-360 407.5,-360 413.5,-366 413.5,-372 413.5,-372 413.5,-384 413.5,-384 413.5,-390 407.5,-396 401.5,-396"/>
+<text text-anchor="middle" x="381" y="-375.5" font-family="sans" font-size="10.00" fill="#000000">bamtobed</text>
+</g>
+<!-- 23&#45;&gt;54 -->
+<g id="edge77" class="edge">
+<title>23&#45;&gt;54</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M397.4485,-431.8314C395.0697,-424.0463 392.2362,-414.7729 389.5967,-406.1347"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="392.8958,-404.954 386.6263,-396.4133 386.2013,-406.9996 392.8958,-404.954"/>
+</g>
+<!-- 24 -->
+<g id="node25" class="node">
+<title>24</title>
+<path fill="none" stroke="#56d8c1" stroke-width="2" d="M437,-540C437,-540 369,-540 369,-540 363,-540 357,-534 357,-528 357,-528 357,-516 357,-516 357,-510 363,-504 369,-504 369,-504 437,-504 437,-504 443,-504 449,-510 449,-516 449,-516 449,-528 449,-528 449,-534 443,-540 437,-540"/>
+<text text-anchor="middle" x="403" y="-519.5" font-family="sans" font-size="10.00" fill="#000000">convert_to_bam</text>
+</g>
+<!-- 24&#45;&gt;23 -->
+<g id="edge32" class="edge">
+<title>24&#45;&gt;23</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M403,-503.8314C403,-496.131 403,-486.9743 403,-478.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="406.5001,-478.4132 403,-468.4133 399.5001,-478.4133 406.5001,-478.4132"/>
+</g>
+<!-- 25 -->
+<g id="node26" class="node">
+<title>25</title>
+<path fill="none" stroke="#56d8a2" stroke-width="2" d="M439,-612C439,-612 367,-612 367,-612 361,-612 355,-606 355,-600 355,-600 355,-588 355,-588 355,-582 361,-576 367,-576 367,-576 439,-576 439,-576 445,-576 451,-582 451,-588 451,-588 451,-600 451,-600 451,-606 445,-612 439,-612"/>
+<text text-anchor="middle" x="403" y="-591.5" font-family="sans" font-size="10.00" fill="#000000">uncollapse_reads</text>
+</g>
+<!-- 25&#45;&gt;24 -->
+<g id="edge33" class="edge">
+<title>25&#45;&gt;24</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M403,-575.8314C403,-568.131 403,-558.9743 403,-550.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="406.5001,-550.4132 403,-540.4133 399.5001,-550.4133 406.5001,-550.4132"/>
+</g>
+<!-- 26 -->
+<g id="node27" class="node">
+<title>26</title>
+<path fill="none" stroke="#5692d8" stroke-width="2" d="M440,-684C440,-684 366,-684 366,-684 360,-684 354,-678 354,-672 354,-672 354,-660 354,-660 354,-654 360,-648 366,-648 366,-648 440,-648 440,-648 446,-648 452,-654 452,-660 452,-660 452,-672 452,-672 452,-678 446,-684 440,-684"/>
+<text text-anchor="middle" x="403" y="-663.5" font-family="sans" font-size="10.00" fill="#000000">remove_inferiors</text>
+</g>
+<!-- 26&#45;&gt;25 -->
+<g id="edge34" class="edge">
+<title>26&#45;&gt;25</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M403,-647.8314C403,-640.131 403,-630.9743 403,-622.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="406.5001,-622.4132 403,-612.4133 399.5001,-622.4133 406.5001,-622.4132"/>
+</g>
+<!-- 27 -->
+<g id="node28" class="node">
+<title>27</title>
+<path fill="none" stroke="#afd856" stroke-width="2" d="M418,-756C418,-756 388,-756 388,-756 382,-756 376,-750 376,-744 376,-744 376,-732 376,-732 376,-726 382,-720 388,-720 388,-720 418,-720 418,-720 424,-720 430,-726 430,-732 430,-732 430,-744 430,-744 430,-750 424,-756 418,-756"/>
+<text text-anchor="middle" x="403" y="-735.5" font-family="sans" font-size="10.00" fill="#000000">sort_id</text>
+</g>
+<!-- 27&#45;&gt;26 -->
+<g id="edge35" class="edge">
+<title>27&#45;&gt;26</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M403,-719.8314C403,-712.131 403,-702.9743 403,-694.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="406.5001,-694.4132 403,-684.4133 399.5001,-694.4133 406.5001,-694.4132"/>
+</g>
+<!-- 28&#45;&gt;27 -->
+<g id="edge36" class="edge">
+<title>28&#45;&gt;27</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M403,-791.8314C403,-784.131 403,-774.9743 403,-766.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="406.5001,-766.4132 403,-756.4133 399.5001,-766.4133 406.5001,-766.4132"/>
+</g>
+<!-- 29 -->
+<g id="node30" class="node">
+<title>29</title>
+<path fill="none" stroke="#70d856" stroke-width="2" d="M433.5,-900C433.5,-900 382.5,-900 382.5,-900 376.5,-900 370.5,-894 370.5,-888 370.5,-888 370.5,-876 370.5,-876 370.5,-870 376.5,-864 382.5,-864 382.5,-864 433.5,-864 433.5,-864 439.5,-864 445.5,-870 445.5,-876 445.5,-876 445.5,-888 445.5,-888 445.5,-894 439.5,-900 433.5,-900"/>
+<text text-anchor="middle" x="408" y="-879.5" font-family="sans" font-size="10.00" fill="#000000">cat_mapping</text>
+</g>
+<!-- 29&#45;&gt;28 -->
+<g id="edge38" class="edge">
+<title>29&#45;&gt;28</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M406.7383,-863.8314C406.2035,-856.131 405.5677,-846.9743 404.9734,-838.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="408.4632,-838.1467 404.2787,-828.4133 401.48,-838.6317 408.4632,-838.1467"/>
+</g>
+<!-- 30&#45;&gt;29 -->
+<g id="edge39" class="edge">
+<title>30&#45;&gt;29</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M717.4283,-946.0196C653.3338,-932.7587 525.0785,-906.2231 455.5104,-891.8297"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="456.1884,-888.396 445.6867,-889.7972 454.7701,-895.2508 456.1884,-888.396"/>
+</g>
+<!-- 31 -->
+<g id="node32" class="node">
+<title>31</title>
+<path fill="none" stroke="#a7d856" stroke-width="2" d="M827.5,-1044C827.5,-1044 684.5,-1044 684.5,-1044 678.5,-1044 672.5,-1038 672.5,-1032 672.5,-1032 672.5,-1020 672.5,-1020 672.5,-1014 678.5,-1008 684.5,-1008 684.5,-1008 827.5,-1008 827.5,-1008 833.5,-1008 839.5,-1014 839.5,-1020 839.5,-1020 839.5,-1032 839.5,-1032 839.5,-1038 833.5,-1044 827.5,-1044"/>
+<text text-anchor="middle" x="756" y="-1023.5" font-family="sans" font-size="10.00" fill="#000000">remove_headers_transcriptome</text>
+</g>
+<!-- 31&#45;&gt;30 -->
+<g id="edge41" class="edge">
+<title>31&#45;&gt;30</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M756,-1007.8314C756,-1000.131 756,-990.9743 756,-982.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="759.5001,-982.4132 756,-972.4133 752.5001,-982.4133 759.5001,-982.4132"/>
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+<!-- 32 -->
+<g id="node33" class="node">
+<title>32</title>
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+<text text-anchor="middle" x="756" y="-1095.5" font-family="sans" font-size="10.00" fill="#000000">filter_nh_transcriptome</text>
+</g>
+<!-- 32&#45;&gt;31 -->
+<g id="edge43" class="edge">
+<title>32&#45;&gt;31</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M756,-1079.8314C756,-1072.131 756,-1062.9743 756,-1054.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="759.5001,-1054.4132 756,-1044.4133 752.5001,-1054.4133 759.5001,-1054.4132"/>
+</g>
+<!-- 33 -->
+<g id="node34" class="node">
+<title>33</title>
+<path fill="none" stroke="#566bd8" stroke-width="2" d="M818,-1188C818,-1188 694,-1188 694,-1188 688,-1188 682,-1182 682,-1176 682,-1176 682,-1164 682,-1164 682,-1158 688,-1152 694,-1152 694,-1152 818,-1152 818,-1152 824,-1152 830,-1158 830,-1164 830,-1164 830,-1176 830,-1176 830,-1182 824,-1188 818,-1188"/>
+<text text-anchor="middle" x="756" y="-1167.5" font-family="sans" font-size="10.00" fill="#000000">merge_transcriptome_maps</text>
+</g>
+<!-- 33&#45;&gt;32 -->
+<g id="edge44" class="edge">
+<title>33&#45;&gt;32</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M756,-1151.8314C756,-1144.131 756,-1134.9743 756,-1126.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="759.5001,-1126.4132 756,-1116.4133 752.5001,-1126.4133 759.5001,-1126.4132"/>
+</g>
+<!-- 34&#45;&gt;33 -->
+<g id="edge45" class="edge">
+<title>34&#45;&gt;33</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M852.0684,-1295.7623C832.8104,-1270.5518 797.9454,-1224.9103 775.9338,-1196.0952"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="778.6703,-1193.9117 769.8185,-1188.0896 773.1075,-1198.161 778.6703,-1193.9117"/>
+</g>
+<!-- 35 -->
+<g id="node36" class="node">
+<title>35</title>
+<path fill="none" stroke="#56d0d8" stroke-width="2" d="M679.5,-1548C679.5,-1548 618.5,-1548 618.5,-1548 612.5,-1548 606.5,-1542 606.5,-1536 606.5,-1536 606.5,-1524 606.5,-1524 606.5,-1518 612.5,-1512 618.5,-1512 618.5,-1512 679.5,-1512 679.5,-1512 685.5,-1512 691.5,-1518 691.5,-1524 691.5,-1524 691.5,-1536 691.5,-1536 691.5,-1542 685.5,-1548 679.5,-1548"/>
+<text text-anchor="middle" x="649" y="-1527.5" font-family="sans" font-size="10.00" fill="#000000">fastx_collapser</text>
+</g>
+<!-- 35&#45;&gt;34 -->
+<g id="edge47" class="edge">
+<title>35&#45;&gt;34</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M677.2267,-1511.9229C691.8001,-1502.0446 709.5126,-1489.1635 724,-1476 737.0022,-1464.1859 807.411,-1382.4476 843.9555,-1339.7906"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="846.7299,-1341.9317 850.5748,-1332.0591 841.4125,-1337.3791 846.7299,-1341.9317"/>
+</g>
+<!-- 41 -->
+<g id="node42" class="node">
+<title>41</title>
+<path fill="none" stroke="#5682d8" stroke-width="2" d="M703,-1476C703,-1476 595,-1476 595,-1476 589,-1476 583,-1470 583,-1464 583,-1464 583,-1452 583,-1452 583,-1446 589,-1440 595,-1440 595,-1440 703,-1440 703,-1440 709,-1440 715,-1446 715,-1452 715,-1452 715,-1464 715,-1464 715,-1470 709,-1476 703,-1476"/>
+<text text-anchor="middle" x="649" y="-1455.5" font-family="sans" font-size="10.00" fill="#000000">filter_fasta_for_oligomap</text>
+</g>
+<!-- 35&#45;&gt;41 -->
+<g id="edge57" class="edge">
+<title>35&#45;&gt;41</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M649,-1511.8314C649,-1504.131 649,-1494.9743 649,-1486.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="652.5001,-1486.4132 649,-1476.4133 645.5001,-1486.4133 652.5001,-1486.4132"/>
+</g>
+<!-- 35&#45;&gt;46 -->
+<g id="edge64" class="edge">
+<title>35&#45;&gt;46</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M606.4082,-1515.6028C575.6693,-1505.2122 533.6588,-1491.0114 499.0422,-1479.31"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="500.0843,-1475.9678 489.4901,-1476.0811 497.8426,-1482.5992 500.0843,-1475.9678"/>
+</g>
+<!-- 36 -->
+<g id="node37" class="node">
+<title>36</title>
+<path fill="none" stroke="#d87d56" stroke-width="2" d="M665.5,-1620C665.5,-1620 632.5,-1620 632.5,-1620 626.5,-1620 620.5,-1614 620.5,-1608 620.5,-1608 620.5,-1596 620.5,-1596 620.5,-1590 626.5,-1584 632.5,-1584 632.5,-1584 665.5,-1584 665.5,-1584 671.5,-1584 677.5,-1590 677.5,-1596 677.5,-1596 677.5,-1608 677.5,-1608 677.5,-1614 671.5,-1620 665.5,-1620"/>
+<text text-anchor="middle" x="649" y="-1599.5" font-family="sans" font-size="10.00" fill="#000000">cutadapt</text>
+</g>
+<!-- 36&#45;&gt;35 -->
+<g id="edge50" class="edge">
+<title>36&#45;&gt;35</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M649,-1583.8314C649,-1576.131 649,-1566.9743 649,-1558.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="652.5001,-1558.4132 649,-1548.4133 645.5001,-1558.4133 652.5001,-1558.4132"/>
+</g>
+<!-- 37 -->
+<g id="node38" class="node">
+<title>37</title>
+<path fill="none" stroke="#56d89a" stroke-width="2" d="M682,-1692C682,-1692 616,-1692 616,-1692 610,-1692 604,-1686 604,-1680 604,-1680 604,-1668 604,-1668 604,-1662 610,-1656 616,-1656 616,-1656 682,-1656 682,-1656 688,-1656 694,-1662 694,-1668 694,-1668 694,-1680 694,-1680 694,-1686 688,-1692 682,-1692"/>
+<text text-anchor="middle" x="649" y="-1671.5" font-family="sans" font-size="10.00" fill="#000000">fasta_formatter</text>
+</g>
+<!-- 37&#45;&gt;36 -->
+<g id="edge51" class="edge">
+<title>37&#45;&gt;36</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M649,-1655.8314C649,-1648.131 649,-1638.9743 649,-1630.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="652.5001,-1630.4132 649,-1620.4133 645.5001,-1630.4133 652.5001,-1630.4132"/>
+</g>
+<!-- 38 -->
+<g id="node39" class="node">
+<title>38</title>
+<path fill="none" stroke="#56d8d0" stroke-width="2" d="M664,-1764C664,-1764 634,-1764 634,-1764 628,-1764 622,-1758 622,-1752 622,-1752 622,-1740 622,-1740 622,-1734 628,-1728 634,-1728 634,-1728 664,-1728 664,-1728 670,-1728 676,-1734 676,-1740 676,-1740 676,-1752 676,-1752 676,-1758 670,-1764 664,-1764"/>
+<text text-anchor="middle" x="649" y="-1743.5" font-family="sans" font-size="10.00" fill="#000000">start</text>
+</g>
+<!-- 38&#45;&gt;37 -->
+<g id="edge52" class="edge">
+<title>38&#45;&gt;37</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M649,-1727.8314C649,-1720.131 649,-1710.9743 649,-1702.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="652.5001,-1702.4132 649,-1692.4133 645.5001,-1702.4133 652.5001,-1702.4132"/>
+</g>
+<!-- 39 -->
+<g id="node40" class="node">
+<title>39</title>
+<path fill="none" stroke="#97d856" stroke-width="2" d="M752.5,-1260C752.5,-1260 611.5,-1260 611.5,-1260 605.5,-1260 599.5,-1254 599.5,-1248 599.5,-1248 599.5,-1236 599.5,-1236 599.5,-1230 605.5,-1224 611.5,-1224 611.5,-1224 752.5,-1224 752.5,-1224 758.5,-1224 764.5,-1230 764.5,-1236 764.5,-1236 764.5,-1248 764.5,-1248 764.5,-1254 758.5,-1260 752.5,-1260"/>
+<text text-anchor="middle" x="682" y="-1239.5" font-family="sans" font-size="10.00" fill="#000000">oligomap_transcriptome_toSAM</text>
+</g>
+<!-- 39&#45;&gt;33 -->
+<g id="edge46" class="edge">
+<title>39&#45;&gt;33</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M700.6733,-1223.8314C709.5249,-1215.219 720.2486,-1204.7851 729.8895,-1195.4048"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="732.6061,-1197.645 737.3326,-1188.1628 727.7246,-1192.6279 732.6061,-1197.645"/>
+</g>
+<!-- 40&#45;&gt;39 -->
+<g id="edge54" class="edge">
+<title>40&#45;&gt;39</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M627.0391,-1367.862C615.446,-1358.6621 603.2598,-1346.3809 597,-1332 590.6142,-1317.3296 589.2953,-1310.0228 597,-1296 603.91,-1283.4235 615.1267,-1273.3606 627.1782,-1265.4922"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="629.2922,-1268.3047 636.0514,-1260.1461 625.6797,-1262.3089 629.2922,-1268.3047"/>
+</g>
+<!-- 42 -->
+<g id="node43" class="node">
+<title>42</title>
+<path fill="none" stroke="#d89556" stroke-width="2" d="M746.5,-1332C746.5,-1332 617.5,-1332 617.5,-1332 611.5,-1332 605.5,-1326 605.5,-1320 605.5,-1320 605.5,-1308 605.5,-1308 605.5,-1302 611.5,-1296 617.5,-1296 617.5,-1296 746.5,-1296 746.5,-1296 752.5,-1296 758.5,-1302 758.5,-1308 758.5,-1308 758.5,-1320 758.5,-1320 758.5,-1326 752.5,-1332 746.5,-1332"/>
+<text text-anchor="middle" x="682" y="-1311.5" font-family="sans" font-size="10.00" fill="#000000">sort_transcriptome_oligomap</text>
+</g>
+<!-- 40&#45;&gt;42 -->
+<g id="edge58" class="edge">
+<title>40&#45;&gt;42</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M661.8132,-1367.8314C664.7644,-1359.9617 668.2858,-1350.5712 671.555,-1341.8533"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="674.8609,-1343.0055 675.095,-1332.4133 668.3066,-1340.5476 674.8609,-1343.0055"/>
+</g>
+<!-- 41&#45;&gt;40 -->
+<g id="edge55" class="edge">
+<title>41&#45;&gt;40</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M650.5141,-1439.8314C651.1558,-1432.131 651.9188,-1422.9743 652.6319,-1414.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="656.1229,-1414.6694 653.4656,-1404.4133 649.1471,-1414.088 656.1229,-1414.6694"/>
+</g>
+<!-- 41&#45;&gt;48 -->
+<g id="edge68" class="edge">
+<title>41&#45;&gt;48</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M593.7687,-1439.9243C563.4319,-1429.9959 525.6335,-1417.6255 493.8945,-1407.2382"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="494.8467,-1403.8672 484.254,-1404.0831 492.6694,-1410.52 494.8467,-1403.8672"/>
+</g>
+<!-- 42&#45;&gt;39 -->
+<g id="edge53" class="edge">
+<title>42&#45;&gt;39</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M682,-1295.8314C682,-1288.131 682,-1278.9743 682,-1270.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="685.5001,-1270.4132 682,-1260.4133 678.5001,-1270.4133 685.5001,-1270.4132"/>
+</g>
+<!-- 43 -->
+<g id="node44" class="node">
+<title>43</title>
+<path fill="none" stroke="#d8d356" stroke-width="2" d="M466,-972C466,-972 350,-972 350,-972 344,-972 338,-966 338,-960 338,-960 338,-948 338,-948 338,-942 344,-936 350,-936 350,-936 466,-936 466,-936 472,-936 478,-942 478,-948 478,-948 478,-960 478,-960 478,-966 472,-972 466,-972"/>
+<text text-anchor="middle" x="408" y="-951.5" font-family="sans" font-size="10.00" fill="#000000">remove_headers_genome</text>
+</g>
+<!-- 43&#45;&gt;29 -->
+<g id="edge40" class="edge">
+<title>43&#45;&gt;29</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M408,-935.8314C408,-928.131 408,-918.9743 408,-910.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="411.5001,-910.4132 408,-900.4133 404.5001,-910.4133 411.5001,-910.4132"/>
+</g>
+<!-- 44 -->
+<g id="node45" class="node">
+<title>44</title>
+<path fill="none" stroke="#68d856" stroke-width="2" d="M445.5,-1116C445.5,-1116 370.5,-1116 370.5,-1116 364.5,-1116 358.5,-1110 358.5,-1104 358.5,-1104 358.5,-1092 358.5,-1092 358.5,-1086 364.5,-1080 370.5,-1080 370.5,-1080 445.5,-1080 445.5,-1080 451.5,-1080 457.5,-1086 457.5,-1092 457.5,-1092 457.5,-1104 457.5,-1104 457.5,-1110 451.5,-1116 445.5,-1116"/>
+<text text-anchor="middle" x="408" y="-1095.5" font-family="sans" font-size="10.00" fill="#000000">nh_filter_genome</text>
+</g>
+<!-- 44&#45;&gt;43 -->
+<g id="edge59" class="edge">
+<title>44&#45;&gt;43</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M408,-1079.7623C408,-1055.201 408,-1011.2474 408,-982.3541"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="411.5001,-982.0896 408,-972.0896 404.5001,-982.0897 411.5001,-982.0896"/>
+</g>
+<!-- 45 -->
+<g id="node46" class="node">
+<title>45</title>
+<path fill="none" stroke="#56a2d8" stroke-width="2" d="M456.5,-1188C456.5,-1188 359.5,-1188 359.5,-1188 353.5,-1188 347.5,-1182 347.5,-1176 347.5,-1176 347.5,-1164 347.5,-1164 347.5,-1158 353.5,-1152 359.5,-1152 359.5,-1152 456.5,-1152 456.5,-1152 462.5,-1152 468.5,-1158 468.5,-1164 468.5,-1164 468.5,-1176 468.5,-1176 468.5,-1182 462.5,-1188 456.5,-1188"/>
+<text text-anchor="middle" x="408" y="-1167.5" font-family="sans" font-size="10.00" fill="#000000">merge_genome_maps</text>
+</g>
+<!-- 45&#45;&gt;44 -->
+<g id="edge60" class="edge">
+<title>45&#45;&gt;44</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M408,-1151.8314C408,-1144.131 408,-1134.9743 408,-1126.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="411.5001,-1126.4132 408,-1116.4133 404.5001,-1126.4133 411.5001,-1126.4132"/>
+</g>
+<!-- 46&#45;&gt;45 -->
+<g id="edge61" class="edge">
+<title>46&#45;&gt;45</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M387.4301,-1439.9133C371.5231,-1431.4865 355.5085,-1419.7574 346,-1404 304.6269,-1335.4368 302.6745,-1295.8662 338,-1224 343.8234,-1212.1528 353.6351,-1202.171 364.0978,-1194.1383"/>
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+</g>
+<!-- 47 -->
+<g id="node48" class="node">
+<title>47</title>
+<path fill="none" stroke="#b6d856" stroke-width="2" d="M473,-1260C473,-1260 359,-1260 359,-1260 353,-1260 347,-1254 347,-1248 347,-1248 347,-1236 347,-1236 347,-1230 353,-1224 359,-1224 359,-1224 473,-1224 473,-1224 479,-1224 485,-1230 485,-1236 485,-1236 485,-1248 485,-1248 485,-1254 479,-1260 473,-1260"/>
+<text text-anchor="middle" x="416" y="-1239.5" font-family="sans" font-size="10.00" fill="#000000">oligomap_genome_toSAM</text>
+</g>
+<!-- 47&#45;&gt;45 -->
+<g id="edge62" class="edge">
+<title>47&#45;&gt;45</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M413.9813,-1223.8314C413.1257,-1216.131 412.1083,-1206.9743 411.1574,-1198.4166"/>
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+</g>
+<!-- 48&#45;&gt;47 -->
+<g id="edge67" class="edge">
+<title>48&#45;&gt;47</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M403.9572,-1367.8695C393.188,-1358.5148 381.7654,-1346.105 376,-1332 369.9462,-1317.1895 370.9856,-1311.1939 376,-1296 379.2908,-1286.0288 385.2116,-1276.3944 391.5064,-1268.0924"/>
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+</g>
+<!-- 49 -->
+<g id="node50" class="node">
+<title>49</title>
+<path fill="none" stroke="#56b1d8" stroke-width="2" d="M499,-1332C499,-1332 397,-1332 397,-1332 391,-1332 385,-1326 385,-1320 385,-1320 385,-1308 385,-1308 385,-1302 391,-1296 397,-1296 397,-1296 499,-1296 499,-1296 505,-1296 511,-1302 511,-1308 511,-1308 511,-1320 511,-1320 511,-1326 505,-1332 499,-1332"/>
+<text text-anchor="middle" x="448" y="-1311.5" font-family="sans" font-size="10.00" fill="#000000">sort_genome_oligomap</text>
+</g>
+<!-- 48&#45;&gt;49 -->
+<g id="edge70" class="edge">
+<title>48&#45;&gt;49</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M433.7945,-1367.8314C435.8489,-1360.0463 438.296,-1350.7729 440.5756,-1342.1347"/>
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+</g>
+<!-- 49&#45;&gt;47 -->
+<g id="edge66" class="edge">
+<title>49&#45;&gt;47</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M439.925,-1295.8314C436.3898,-1287.8771 432.164,-1278.369 428.2544,-1269.5723"/>
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+</g>
+<!-- 50 -->
+<g id="node51" class="node">
+<title>50</title>
+<path fill="none" stroke="#d87556" stroke-width="2" d="M455,-108C455,-108 399,-108 399,-108 393,-108 387,-102 387,-96 387,-96 387,-84 387,-84 387,-78 393,-72 399,-72 399,-72 455,-72 455,-72 461,-72 467,-78 467,-84 467,-84 467,-96 467,-96 467,-102 461,-108 455,-108"/>
+<text text-anchor="middle" x="427" y="-87.5" font-family="sans" font-size="10.00" fill="#000000">merge_tables</text>
+</g>
+<!-- 50&#45;&gt;0 -->
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+<title>50&#45;&gt;0</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M436.3367,-71.8314C440.4243,-63.8771 445.3104,-54.369 449.8309,-45.5723"/>
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+</g>
+<!-- 51 -->
+<g id="node52" class="node">
+<title>51</title>
+<path fill="none" stroke="#568ad8" stroke-width="2" d="M350.5,-180C350.5,-180 299.5,-180 299.5,-180 293.5,-180 287.5,-174 287.5,-168 287.5,-168 287.5,-156 287.5,-156 287.5,-150 293.5,-144 299.5,-144 299.5,-144 350.5,-144 350.5,-144 356.5,-144 362.5,-150 362.5,-156 362.5,-156 362.5,-168 362.5,-168 362.5,-174 356.5,-180 350.5,-180"/>
+<text text-anchor="middle" x="325" y="-159.5" font-family="sans" font-size="10.00" fill="#000000">quant_mirna</text>
+</g>
+<!-- 51&#45;&gt;50 -->
+<g id="edge72" class="edge">
+<title>51&#45;&gt;50</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M350.7389,-143.8314C363.5437,-134.7927 379.1909,-123.7476 392.9719,-114.0198"/>
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+<!-- 52&#45;&gt;51 -->
+<g id="edge73" class="edge">
+<title>52&#45;&gt;51</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M346.6821,-215.8314C343.5124,-207.9617 339.73,-198.5712 336.2187,-189.8533"/>
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+</g>
+<!-- 55 -->
+<g id="node56" class="node">
+<title>55</title>
+<path fill="none" stroke="#80d856" stroke-width="2" d="M461,-180C461,-180 393,-180 393,-180 387,-180 381,-174 381,-168 381,-168 381,-156 381,-156 381,-150 387,-144 393,-144 393,-144 461,-144 461,-144 467,-144 473,-150 473,-156 473,-156 473,-168 473,-168 473,-174 467,-180 461,-180"/>
+<text text-anchor="middle" x="427" y="-159.5" font-family="sans" font-size="10.00" fill="#000000">quant_mirna_pri</text>
+</g>
+<!-- 52&#45;&gt;55 -->
+<g id="edge78" class="edge">
+<title>52&#45;&gt;55</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M372.421,-215.8314C381.1529,-207.219 391.7317,-196.7851 401.2423,-187.4048"/>
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+<!-- 53 -->
+<g id="node54" class="node">
+<title>53</title>
+<path fill="none" stroke="#8fd856" stroke-width="2" d="M410.5,-324C410.5,-324 343.5,-324 343.5,-324 337.5,-324 331.5,-318 331.5,-312 331.5,-312 331.5,-300 331.5,-300 331.5,-294 337.5,-288 343.5,-288 343.5,-288 410.5,-288 410.5,-288 416.5,-288 422.5,-294 422.5,-300 422.5,-300 422.5,-312 422.5,-312 422.5,-318 416.5,-324 410.5,-324"/>
+<text text-anchor="middle" x="377" y="-303.5" font-family="sans" font-size="10.00" fill="#000000">sort_alignments</text>
+</g>
+<!-- 53&#45;&gt;52 -->
+<g id="edge75" class="edge">
+<title>53&#45;&gt;52</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M371.1961,-287.8314C368.7092,-280.0463 365.7469,-270.7729 362.9875,-262.1347"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="366.2591,-260.874 359.882,-252.4133 359.591,-263.0041 366.2591,-260.874"/>
+</g>
+<!-- 54&#45;&gt;53 -->
+<g id="edge76" class="edge">
+<title>54&#45;&gt;53</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M379.9906,-359.8314C379.5628,-352.131 379.0541,-342.9743 378.5787,-334.4166"/>
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+</g>
+<!-- 55&#45;&gt;50 -->
+<g id="edge71" class="edge">
+<title>55&#45;&gt;50</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M427,-143.8314C427,-136.131 427,-126.9743 427,-118.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="430.5001,-118.4132 427,-108.4133 423.5001,-118.4133 430.5001,-118.4132"/>
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+</g>
+</svg>

images/rule_graph_map.svg

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-<title>1</title>
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-<!-- 1&#45;&gt;0 -->
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-<title>1&#45;&gt;0</title>
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-<g id="node3" class="node">
-<title>2</title>
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-<!-- 2&#45;&gt;1 -->
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-<title>2&#45;&gt;1</title>
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-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="344.5001,-118.4132 341,-108.4133 337.5001,-118.4133 344.5001,-118.4132"/>
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-<g id="node4" class="node">
-<title>3</title>
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-<!-- 3&#45;&gt;2 -->
-<g id="edge3" class="edge">
-<title>3&#45;&gt;2</title>
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-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="344.5001,-190.4132 341,-180.4133 337.5001,-190.4133 344.5001,-190.4132"/>
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-<!-- 4 -->
-<g id="node5" class="node">
-<title>4</title>
-<path fill="none" stroke="#56d8c1" stroke-width="2" d="M379.5,-324C379.5,-324 302.5,-324 302.5,-324 296.5,-324 290.5,-318 290.5,-312 290.5,-312 290.5,-300 290.5,-300 290.5,-294 296.5,-288 302.5,-288 302.5,-288 379.5,-288 379.5,-288 385.5,-288 391.5,-294 391.5,-300 391.5,-300 391.5,-312 391.5,-312 391.5,-318 385.5,-324 379.5,-324"/>
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-<!-- 4&#45;&gt;3 -->
-<g id="edge4" class="edge">
-<title>4&#45;&gt;3</title>
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-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="344.5001,-262.4132 341,-252.4133 337.5001,-262.4133 344.5001,-262.4132"/>
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-<!-- 5 -->
-<g id="node6" class="node">
-<title>5</title>
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-<!-- 5&#45;&gt;4 -->
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-<title>5&#45;&gt;4</title>
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-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="344.5001,-334.4132 341,-324.4133 337.5001,-334.4133 344.5001,-334.4132"/>
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-<!-- 6 -->
-<g id="node7" class="node">
-<title>6</title>
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-<title>6&#45;&gt;5</title>
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-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="344.5001,-406.4132 341,-396.4133 337.5001,-406.4133 344.5001,-406.4132"/>
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-<g id="node8" class="node">
-<title>7</title>
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-<title>7&#45;&gt;6</title>
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-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="344.5001,-478.4132 341,-468.4133 337.5001,-478.4133 344.5001,-478.4132"/>
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-<g id="node9" class="node">
-<title>8</title>
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-<text text-anchor="middle" x="341" y="-591.5" font-family="sans" font-size="10.00" fill="#000000">cat_mapping</text>
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-<!-- 8&#45;&gt;7 -->
-<g id="edge8" class="edge">
-<title>8&#45;&gt;7</title>
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-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="344.5001,-550.4132 341,-540.4133 337.5001,-550.4133 344.5001,-550.4132"/>
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-<g id="node10" class="node">
-<title>9</title>
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-<text text-anchor="middle" x="276" y="-663.5" font-family="sans" font-size="10.00" fill="#000000">trans_to_gen</text>
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-<g id="edge9" class="edge">
-<title>9&#45;&gt;8</title>
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-<title>10</title>
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-<title>10&#45;&gt;9</title>
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-<title>11&#45;&gt;10</title>
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-<title>12&#45;&gt;11</title>
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-<title>13&#45;&gt;12</title>
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-<title>14&#45;&gt;13</title>
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-<g id="node17" class="node">
-<title>16</title>
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-<title>16&#45;&gt;15</title>
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-<g id="node18" class="node">
-<title>17</title>
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-<title>17&#45;&gt;16</title>
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-<g id="node19" class="node">
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-<title>18&#45;&gt;12</title>
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-<g id="node20" class="node">
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-<g id="node22" class="node">
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-<title>19&#45;&gt;21</title>
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-<!-- 27 -->
-<g id="node28" class="node">
-<title>27</title>
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-<title>20&#45;&gt;27</title>
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-<!-- 21&#45;&gt;18 -->
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-<title>21&#45;&gt;18</title>
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-<g id="node23" class="node">
-<title>22</title>
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-<title>22&#45;&gt;8</title>
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-<g id="node24" class="node">
-<title>23</title>
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-<g id="node29" class="node">
-<title>28</title>
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-<title>27&#45;&gt;28</title>
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images/rule_graph_prepare.svg

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-<!-- 4 -->
-<g id="node5" class="node">
-<title>4</title>
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-<text text-anchor="middle" x="308.5" y="-735.5" font-family="sans" font-size="10.00" fill="#000000">genome_process</text>
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-<g id="edge9" class="edge">
-<title>4&#45;&gt;3</title>
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-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="275.8599,-261.9376 271.7432,-252.1753 268.8736,-262.3741 275.8599,-261.9376"/>
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-<!-- 6 -->
-<g id="node7" class="node">
-<title>6</title>
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-<text text-anchor="middle" x="95.5" y="-519.5" font-family="sans" font-size="10.00" fill="#000000">generate_segemehl_index_genome</text>
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-<!-- 4&#45;&gt;6 -->
-<g id="edge11" class="edge">
-<title>4&#45;&gt;6</title>
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-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="112.7713,-547.0911 104.8776,-540.0242 106.6414,-550.4712 112.7713,-547.0911"/>
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-<!-- 9 -->
-<g id="node10" class="node">
-<title>9</title>
-<path fill="none" stroke="#566bd8" stroke-width="2" d="M236,-468C236,-468 129,-468 129,-468 123,-468 117,-462 117,-456 117,-456 117,-444 117,-444 117,-438 123,-432 129,-432 129,-432 236,-432 236,-432 242,-432 248,-438 248,-444 248,-444 248,-456 248,-456 248,-462 242,-468 236,-468"/>
-<text text-anchor="middle" x="182.5" y="-447.5" font-family="sans" font-size="10.00" fill="#000000">create_header_genome</text>
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-<!-- 4&#45;&gt;9 -->
-<g id="edge14" class="edge">
-<title>4&#45;&gt;9</title>
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-<!-- 13 -->
-<g id="node14" class="node">
-<title>13</title>
-<path fill="none" stroke="#b6d856" stroke-width="2" d="M366.5,-684C366.5,-684 316.5,-684 316.5,-684 310.5,-684 304.5,-678 304.5,-672 304.5,-672 304.5,-660 304.5,-660 304.5,-654 310.5,-648 316.5,-648 316.5,-648 366.5,-648 366.5,-648 372.5,-648 378.5,-654 378.5,-660 378.5,-660 378.5,-672 378.5,-672 378.5,-678 372.5,-684 366.5,-684"/>
-<text text-anchor="middle" x="341.5" y="-663.5" font-family="sans" font-size="10.00" fill="#000000">mirna_anno</text>
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-<!-- 4&#45;&gt;13 -->
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-<title>4&#45;&gt;13</title>
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-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="332.0757,-694.9622 333.0606,-684.4133 325.7123,-692.0456 332.0757,-694.9622"/>
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-<g id="node15" class="node">
-<title>14</title>
-<path fill="none" stroke="#d85656" stroke-width="2" d="M440,-684C440,-684 409,-684 409,-684 403,-684 397,-678 397,-672 397,-672 397,-660 397,-660 397,-654 403,-648 409,-648 409,-648 440,-648 440,-648 446,-648 452,-654 452,-660 452,-660 452,-672 452,-672 452,-678 446,-684 440,-684"/>
-<text text-anchor="middle" x="424.5" y="-663.5" font-family="sans" font-size="10.00" fill="#000000">dict_chr</text>
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-<!-- 4&#45;&gt;14 -->
-<g id="edge20" class="edge">
-<title>4&#45;&gt;14</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M337.7717,-719.8314C353.0619,-710.3409 371.9156,-698.6386 388.1347,-688.5716"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="390.1842,-691.4189 396.8349,-683.1715 386.4927,-685.4714 390.1842,-691.4189"/>
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-<!-- 21 -->
-<g id="node22" class="node">
-<title>21</title>
-<path fill="none" stroke="#88d856" stroke-width="2" d="M592.5,-612C592.5,-612 506.5,-612 506.5,-612 500.5,-612 494.5,-606 494.5,-600 494.5,-600 494.5,-588 494.5,-588 494.5,-582 500.5,-576 506.5,-576 506.5,-576 592.5,-576 592.5,-576 598.5,-576 604.5,-582 604.5,-588 604.5,-588 604.5,-600 604.5,-600 604.5,-606 598.5,-612 592.5,-612"/>
-<text text-anchor="middle" x="549.5" y="-591.5" font-family="sans" font-size="10.00" fill="#000000">create_index_fasta</text>
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-<!-- 4&#45;&gt;21 -->
-<g id="edge28" class="edge">
-<title>4&#45;&gt;21</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M358.2792,-726.4177C389.2668,-717.7739 429.0656,-703.979 460.5,-684 487.558,-666.8025 512.682,-639.9749 529.2879,-620.0797"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="532.0321,-622.2527 535.6493,-612.2945 526.6116,-617.8235 532.0321,-622.2527"/>
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-<!-- 5 -->
-<g id="node6" class="node">
-<title>5</title>
-<path fill="none" stroke="#56d86b" stroke-width="2" d="M409,-324C409,-324 346,-324 346,-324 340,-324 334,-318 334,-312 334,-312 334,-300 334,-300 334,-294 340,-288 346,-288 346,-288 409,-288 409,-288 415,-288 421,-294 421,-300 421,-300 421,-312 421,-312 421,-318 415,-324 409,-324"/>
-<text text-anchor="middle" x="377.5" y="-303.5" font-family="sans" font-size="10.00" fill="#000000">filter_anno_gtf</text>
-</g>
-<!-- 5&#45;&gt;3 -->
-<g id="edge10" class="edge">
-<title>5&#45;&gt;3</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M350.4994,-287.8314C337.0669,-278.7927 320.6527,-267.7476 306.1961,-258.0198"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="307.7425,-254.8418 297.492,-252.1628 303.8346,-260.6494 307.7425,-254.8418"/>
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-<!-- 8 -->
-<g id="node9" class="node">
-<title>8</title>
-<path fill="none" stroke="#d89c56" stroke-width="2" d="M438.5,-252C438.5,-252 376.5,-252 376.5,-252 370.5,-252 364.5,-246 364.5,-240 364.5,-240 364.5,-228 364.5,-228 364.5,-222 370.5,-216 376.5,-216 376.5,-216 438.5,-216 438.5,-216 444.5,-216 450.5,-222 450.5,-228 450.5,-228 450.5,-240 450.5,-240 450.5,-246 444.5,-252 438.5,-252"/>
-<text text-anchor="middle" x="407.5" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">get_exons_gtf</text>
-</g>
-<!-- 5&#45;&gt;8 -->
-<g id="edge13" class="edge">
-<title>5&#45;&gt;8</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M385.0703,-287.8314C388.3493,-279.9617 392.262,-270.5712 395.8945,-261.8533"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="399.2124,-262.9902 399.8278,-252.4133 392.7508,-260.2979 399.2124,-262.9902"/>
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-<!-- 6&#45;&gt;0 -->
-<g id="edge4" class="edge">
-<title>6&#45;&gt;0</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M94.0496,-503.8284C91.9993,-476.5296 88.5,-423.3034 88.5,-378 88.5,-378 88.5,-378 88.5,-162 88.5,-119.2408 90.4989,-100.3597 122.5,-72 149.3909,-48.169 249.9753,-30.8466 305.3538,-22.8826"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="306.0511,-26.319 315.466,-21.4601 305.0759,-19.3873 306.0511,-26.319"/>
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-<!-- 7 -->
-<g id="node8" class="node">
-<title>7</title>
-<path fill="none" stroke="#56d8c9" stroke-width="2" d="M438.5,-108C438.5,-108 404.5,-108 404.5,-108 398.5,-108 392.5,-102 392.5,-96 392.5,-96 392.5,-84 392.5,-84 392.5,-78 398.5,-72 404.5,-72 404.5,-72 438.5,-72 438.5,-72 444.5,-72 450.5,-78 450.5,-84 450.5,-84 450.5,-96 450.5,-96 450.5,-102 444.5,-108 438.5,-108"/>
-<text text-anchor="middle" x="421.5" y="-87.5" font-family="sans" font-size="10.00" fill="#000000">gtftobed</text>
-</g>
-<!-- 7&#45;&gt;0 -->
-<g id="edge6" class="edge">
-<title>7&#45;&gt;0</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M401.565,-71.8314C392.0217,-63.1337 380.4401,-52.5783 370.0694,-43.1265"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="372.1772,-40.3121 362.4287,-36.1628 367.462,-45.4857 372.1772,-40.3121"/>
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-<!-- 8&#45;&gt;7 -->
-<g id="edge12" class="edge">
-<title>8&#45;&gt;7</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M409.2731,-215.7623C411.661,-191.201 415.9343,-147.2474 418.7434,-118.3541"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="422.2571,-118.3814 419.7413,-108.0896 415.29,-117.704 422.2571,-118.3814"/>
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-<!-- 9&#45;&gt;0 -->
-<g id="edge5" class="edge">
-<title>9&#45;&gt;0</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M170.3488,-431.7857C153.8788,-405.2865 126.5,-354.0148 126.5,-306 126.5,-306 126.5,-306 126.5,-162 126.5,-121.1184 117.4647,-101.7545 145.5,-72 167.2281,-48.9395 254.6042,-31.7622 305.3969,-23.4905"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="306.0144,-26.9364 315.3404,-21.9087 304.9147,-20.0233 306.0144,-26.9364"/>
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-<!-- 10 -->
-<g id="node11" class="node">
-<title>10</title>
-<path fill="none" stroke="#d86e56" stroke-width="2" d="M495,-468C495,-468 462,-468 462,-468 456,-468 450,-462 450,-456 450,-456 450,-444 450,-444 450,-438 456,-432 462,-432 462,-432 495,-432 495,-432 501,-432 507,-438 507,-444 507,-444 507,-456 507,-456 507,-462 501,-468 495,-468"/>
-<text text-anchor="middle" x="478.5" y="-447.5" font-family="sans" font-size="10.00" fill="#000000">gfftobed</text>
-</g>
-<!-- 10&#45;&gt;0 -->
-<g id="edge2" class="edge">
-<title>10&#45;&gt;0</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M478.5,-431.8146C478.5,-404.4983 478.5,-351.25 478.5,-306 478.5,-306 478.5,-306 478.5,-162 478.5,-121.1184 484.9901,-103.9619 459.5,-72 439.6741,-47.1403 405.7974,-33.2394 379.5835,-25.7916"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="380.1623,-22.3246 369.6002,-23.1563 378.3757,-29.0927 380.1623,-22.3246"/>
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-<!-- 19 -->
-<g id="node20" class="node">
-<title>19</title>
-<path fill="none" stroke="#56d89a" stroke-width="2" d="M602,-396C602,-396 519,-396 519,-396 513,-396 507,-390 507,-384 507,-384 507,-372 507,-372 507,-366 513,-360 519,-360 519,-360 602,-360 602,-360 608,-360 614,-366 614,-372 614,-372 614,-384 614,-384 614,-390 608,-396 602,-396"/>
-<text text-anchor="middle" x="560.5" y="-375.5" font-family="sans" font-size="10.00" fill="#000000">filter_mature_mirs</text>
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-<!-- 10&#45;&gt;19 -->
-<g id="edge26" class="edge">
-<title>10&#45;&gt;19</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M499.1921,-431.8314C509.1948,-423.0485 521.355,-412.3712 532.1999,-402.8489"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="534.6094,-405.3909 539.8146,-396.1628 529.9908,-400.1308 534.6094,-405.3909"/>
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-<!-- 11 -->
-<g id="node12" class="node">
-<title>11</title>
-<path fill="none" stroke="#56d882" stroke-width="2" d="M489,-540C489,-540 412,-540 412,-540 406,-540 400,-534 400,-528 400,-528 400,-516 400,-516 400,-510 406,-504 412,-504 412,-504 489,-504 489,-504 495,-504 501,-510 501,-516 501,-516 501,-528 501,-528 501,-534 495,-540 489,-540"/>
-<text text-anchor="middle" x="450.5" y="-519.5" font-family="sans" font-size="10.00" fill="#000000">filter_mir_1_anno</text>
-</g>
-<!-- 11&#45;&gt;10 -->
-<g id="edge15" class="edge">
-<title>11&#45;&gt;10</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M457.5656,-503.8314C460.626,-495.9617 464.2779,-486.5712 467.6682,-477.8533"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="470.9768,-479.0019 471.3393,-468.4133 464.4527,-476.4647 470.9768,-479.0019"/>
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-<!-- 12 -->
-<g id="node13" class="node">
-<title>12</title>
-<path fill="none" stroke="#56c9d8" stroke-width="2" d="M461,-612C461,-612 388,-612 388,-612 382,-612 376,-606 376,-600 376,-600 376,-588 376,-588 376,-582 382,-576 388,-576 388,-576 461,-576 461,-576 467,-576 473,-582 473,-588 473,-588 473,-600 473,-600 473,-606 467,-612 461,-612"/>
-<text text-anchor="middle" x="424.5" y="-591.5" font-family="sans" font-size="10.00" fill="#000000">map_chr_names</text>
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-<!-- 12&#45;&gt;11 -->
-<g id="edge16" class="edge">
-<title>12&#45;&gt;11</title>
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-<!-- 13&#45;&gt;12 -->
-<g id="edge17" class="edge">
-<title>13&#45;&gt;12</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M362.4444,-647.8314C372.5691,-639.0485 384.8777,-628.3712 395.8548,-618.8489"/>
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-<!-- 14&#45;&gt;12 -->
-<g id="edge18" class="edge">
-<title>14&#45;&gt;12</title>
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-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="428.0001,-622.4132 424.5,-612.4133 421.0001,-622.4133 428.0001,-622.4132"/>
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-<!-- 15 -->
-<g id="node16" class="node">
-<title>15</title>
-<path fill="none" stroke="#9fd856" stroke-width="2" d="M584.5,-108C584.5,-108 522.5,-108 522.5,-108 516.5,-108 510.5,-102 510.5,-96 510.5,-96 510.5,-84 510.5,-84 510.5,-78 516.5,-72 522.5,-72 522.5,-72 584.5,-72 584.5,-72 590.5,-72 596.5,-78 596.5,-84 596.5,-84 596.5,-96 596.5,-96 596.5,-102 590.5,-108 584.5,-108"/>
-<text text-anchor="middle" x="553.5" y="-87.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_final</text>
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-<!-- 15&#45;&gt;0 -->
-<g id="edge1" class="edge">
-<title>15&#45;&gt;0</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M510.2918,-75.256C471.7195,-62.0939 415.8391,-43.0257 379.3404,-30.5711"/>
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-<!-- 16 -->
-<g id="node17" class="node">
-<title>16</title>
-<path fill="none" stroke="#59d856" stroke-width="2" d="M594.5,-180C594.5,-180 520.5,-180 520.5,-180 514.5,-180 508.5,-174 508.5,-168 508.5,-168 508.5,-156 508.5,-156 508.5,-150 514.5,-144 520.5,-144 520.5,-144 594.5,-144 594.5,-144 600.5,-144 606.5,-150 606.5,-156 606.5,-156 606.5,-168 606.5,-168 606.5,-174 600.5,-180 594.5,-180"/>
-<text text-anchor="middle" x="557.5" y="-159.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_concat</text>
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-<!-- 16&#45;&gt;15 -->
-<g id="edge21" class="edge">
-<title>16&#45;&gt;15</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M556.4906,-143.8314C556.0628,-136.131 555.5541,-126.9743 555.0787,-118.4166"/>
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-<!-- 17 -->
-<g id="node18" class="node">
-<title>17</title>
-<path fill="none" stroke="#70d856" stroke-width="2" d="M599,-252C599,-252 520,-252 520,-252 514,-252 508,-246 508,-240 508,-240 508,-228 508,-228 508,-222 514,-216 520,-216 520,-216 599,-216 599,-216 605,-216 611,-222 611,-228 611,-228 611,-240 611,-240 611,-246 605,-252 599,-252"/>
-<text text-anchor="middle" x="559.5" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_rename</text>
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-<!-- 17&#45;&gt;16 -->
-<g id="edge22" class="edge">
-<title>17&#45;&gt;16</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M558.9953,-215.8314C558.7814,-208.131 558.5271,-198.9743 558.2894,-190.4166"/>
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-<!-- 18 -->
-<g id="node19" class="node">
-<title>18</title>
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-<text text-anchor="middle" x="560.5" y="-303.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno</text>
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-<!-- 18&#45;&gt;17 -->
-<g id="edge23" class="edge">
-<title>18&#45;&gt;17</title>
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-<!-- 19&#45;&gt;18 -->
-<g id="edge24" class="edge">
-<title>19&#45;&gt;18</title>
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images/rule_graph_quantify.svg

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-<g id="node7" class="node">
-<title>6</title>
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-<!-- 3&#45;&gt;6 -->
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-<title>3&#45;&gt;6</title>
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-<g id="node5" class="node">
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-<g id="node6" class="node">
-<title>5</title>
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-<!-- 6&#45;&gt;1 -->
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-</g>
-</svg>

images/workflow_dag.svg

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+<g id="graph0" class="graph" transform="scale(1 1) rotate(0) translate(4 1778)">
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+<polygon fill="#ffffff" stroke="transparent" points="-4,4 -4,-1778 3744.5,-1778 3744.5,4 -4,4"/>
+<!-- 0 -->
+<g id="node1" class="node">
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+<path fill="none" stroke="#68d856" stroke-width="2" stroke-dasharray="5,2" d="M3013,-36C3013,-36 2983,-36 2983,-36 2977,-36 2971,-30 2971,-24 2971,-24 2971,-12 2971,-12 2971,-6 2977,0 2983,0 2983,0 3013,0 3013,0 3019,0 3025,-6 3025,-12 3025,-12 3025,-24 3025,-24 3025,-30 3019,-36 3013,-36"/>
+<text text-anchor="middle" x="2998" y="-15.5" font-family="sans" font-size="10.00" fill="#000000">finish</text>
+</g>
+<!-- 1 -->
+<g id="node2" class="node">
+<title>1</title>
+<path fill="none" stroke="#569ad8" stroke-width="2" stroke-dasharray="5,2" d="M3667.5,-1409C3667.5,-1409 3480.5,-1409 3480.5,-1409 3474.5,-1409 3468.5,-1403 3468.5,-1397 3468.5,-1397 3468.5,-1385 3468.5,-1385 3468.5,-1379 3474.5,-1373 3480.5,-1373 3480.5,-1373 3667.5,-1373 3667.5,-1373 3673.5,-1373 3679.5,-1379 3679.5,-1385 3679.5,-1385 3679.5,-1397 3679.5,-1397 3679.5,-1403 3673.5,-1409 3667.5,-1409"/>
+<text text-anchor="middle" x="3574" y="-1388.5" font-family="sans" font-size="10.00" fill="#000000">generate_segemehl_index_transcriptome</text>
+</g>
+<!-- 1&#45;&gt;0 -->
+<g id="edge1" class="edge">
+<title>1&#45;&gt;0</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3582.483,-1372.81C3594.2246,-1345.9218 3614,-1293.7039 3614,-1247 3614,-1247 3614,-1247 3614,-162 3614,-42.5037 3168.9116,-22.111 3035.4092,-18.6819"/>
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+</g>
+<!-- 82 -->
+<g id="node83" class="node">
+<title>82</title>
+<path fill="none" stroke="#56d8a2" stroke-width="2" stroke-dasharray="5,2" d="M3574,-1337C3574,-1337 3420,-1337 3420,-1337 3414,-1337 3408,-1331 3408,-1325 3408,-1325 3408,-1313 3408,-1313 3408,-1307 3414,-1301 3420,-1301 3420,-1301 3574,-1301 3574,-1301 3580,-1301 3586,-1307 3586,-1313 3586,-1313 3586,-1325 3586,-1325 3586,-1331 3580,-1337 3574,-1337"/>
+<text text-anchor="middle" x="3497" y="-1316.5" font-family="sans" font-size="10.00" fill="#000000">mapping_transcriptome_segemehl</text>
+</g>
+<!-- 1&#45;&gt;82 -->
+<g id="edge147" class="edge">
+<title>1&#45;&gt;82</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3554.5696,-1372.8314C3545.268,-1364.1337 3533.9796,-1353.5783 3523.8714,-1344.1265"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3526.1189,-1341.4363 3516.4241,-1337.1628 3521.3379,-1346.5493 3526.1189,-1341.4363"/>
+</g>
+<!-- 2 -->
+<g id="node3" class="node">
+<title>2</title>
+<path fill="none" stroke="#568ad8" stroke-width="2" stroke-dasharray="5,2" d="M3481.5,-1481C3481.5,-1481 3442.5,-1481 3442.5,-1481 3436.5,-1481 3430.5,-1475 3430.5,-1469 3430.5,-1469 3430.5,-1457 3430.5,-1457 3430.5,-1451 3436.5,-1445 3442.5,-1445 3442.5,-1445 3481.5,-1445 3481.5,-1445 3487.5,-1445 3493.5,-1451 3493.5,-1457 3493.5,-1457 3493.5,-1469 3493.5,-1469 3493.5,-1475 3487.5,-1481 3481.5,-1481"/>
+<text text-anchor="middle" x="3462" y="-1460.5" font-family="sans" font-size="10.00" fill="#000000">trim_fasta</text>
+</g>
+<!-- 2&#45;&gt;1 -->
+<g id="edge11" class="edge">
+<title>2&#45;&gt;1</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3490.2623,-1444.8314C3504.4552,-1435.7074 3521.8282,-1424.539 3537.0636,-1414.7449"/>
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+</g>
+<!-- 2&#45;&gt;82 -->
+<g id="edge146" class="edge">
+<title>2&#45;&gt;82</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3458.3026,-1444.9468C3455.2658,-1426.4363 3452.5554,-1397.036 3460,-1373 3463.0445,-1363.1704 3468.5641,-1353.5387 3474.4271,-1345.1946"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3477.3663,-1347.1092 3480.5719,-1337.011 3471.7686,-1342.9061 3477.3663,-1347.1092"/>
+</g>
+<!-- 88 -->
+<g id="node89" class="node">
+<title>88</title>
+<path fill="none" stroke="#56d8b1" stroke-width="2" stroke-dasharray="5,2" d="M3361.5,-1409C3361.5,-1409 3210.5,-1409 3210.5,-1409 3204.5,-1409 3198.5,-1403 3198.5,-1397 3198.5,-1397 3198.5,-1385 3198.5,-1385 3198.5,-1379 3204.5,-1373 3210.5,-1373 3210.5,-1373 3361.5,-1373 3361.5,-1373 3367.5,-1373 3373.5,-1379 3373.5,-1385 3373.5,-1385 3373.5,-1397 3373.5,-1397 3373.5,-1403 3367.5,-1409 3361.5,-1409"/>
+<text text-anchor="middle" x="3286" y="-1388.5" font-family="sans" font-size="10.00" fill="#000000">mapping_transcriptome_oligomap</text>
+</g>
+<!-- 2&#45;&gt;88 -->
+<g id="edge154" class="edge">
+<title>2&#45;&gt;88</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3430.1277,-1449.9613C3404.921,-1439.6495 3369.1695,-1425.0239 3339.5807,-1412.9194"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3340.7924,-1409.6336 3330.2117,-1409.0866 3338.1419,-1416.1124 3340.7924,-1409.6336"/>
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+<!-- 3 -->
+<g id="node4" class="node">
+<title>3</title>
+<path fill="none" stroke="#d8b456" stroke-width="2" stroke-dasharray="5,2" d="M3523,-1553C3523,-1553 3401,-1553 3401,-1553 3395,-1553 3389,-1547 3389,-1541 3389,-1541 3389,-1529 3389,-1529 3389,-1523 3395,-1517 3401,-1517 3401,-1517 3523,-1517 3523,-1517 3529,-1517 3535,-1523 3535,-1529 3535,-1529 3535,-1541 3535,-1541 3535,-1547 3529,-1553 3523,-1553"/>
+<text text-anchor="middle" x="3462" y="-1532.5" font-family="sans" font-size="10.00" fill="#000000">extract_transcriptome_seqs</text>
+</g>
+<!-- 3&#45;&gt;2 -->
+<g id="edge12" class="edge">
+<title>3&#45;&gt;2</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3462,-1516.8314C3462,-1509.131 3462,-1499.9743 3462,-1491.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3465.5001,-1491.4132 3462,-1481.4133 3458.5001,-1491.4133 3465.5001,-1491.4132"/>
+</g>
+<!-- 4 -->
+<g id="node5" class="node">
+<title>4</title>
+<path fill="none" stroke="#56d89a" stroke-width="2" stroke-dasharray="5,2" d="M2971,-1625C2971,-1625 2899,-1625 2899,-1625 2893,-1625 2887,-1619 2887,-1613 2887,-1613 2887,-1601 2887,-1601 2887,-1595 2893,-1589 2899,-1589 2899,-1589 2971,-1589 2971,-1589 2977,-1589 2983,-1595 2983,-1601 2983,-1601 2983,-1613 2983,-1613 2983,-1619 2977,-1625 2971,-1625"/>
+<text text-anchor="middle" x="2935" y="-1604.5" font-family="sans" font-size="10.00" fill="#000000">genome_process</text>
+</g>
+<!-- 4&#45;&gt;3 -->
+<g id="edge13" class="edge">
+<title>4&#45;&gt;3</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2983.2836,-1600.4704C3058.0228,-1590.3546 3206.235,-1570.2601 3332,-1553 3347.0914,-1550.9288 3363.1666,-1548.7118 3378.6826,-1546.5664"/>
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+</g>
+<!-- 6 -->
+<g id="node7" class="node">
+<title>6</title>
+<path fill="none" stroke="#5673d8" stroke-width="2" stroke-dasharray="5,2" d="M3200,-1553C3200,-1553 3040,-1553 3040,-1553 3034,-1553 3028,-1547 3028,-1541 3028,-1541 3028,-1529 3028,-1529 3028,-1523 3034,-1517 3040,-1517 3040,-1517 3200,-1517 3200,-1517 3206,-1517 3212,-1523 3212,-1529 3212,-1529 3212,-1541 3212,-1541 3212,-1547 3206,-1553 3200,-1553"/>
+<text text-anchor="middle" x="3120" y="-1532.5" font-family="sans" font-size="10.00" fill="#000000">generate_segemehl_index_genome</text>
+</g>
+<!-- 4&#45;&gt;6 -->
+<g id="edge15" class="edge">
+<title>4&#45;&gt;6</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2981.6833,-1588.8314C3006.7559,-1579.0734 3037.8367,-1566.977 3064.1809,-1556.7242"/>
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+</g>
+<!-- 9 -->
+<g id="node10" class="node">
+<title>9</title>
+<path fill="none" stroke="#d86656" stroke-width="2" stroke-dasharray="5,2" d="M2814,-905C2814,-905 2710,-905 2710,-905 2704,-905 2698,-899 2698,-893 2698,-893 2698,-881 2698,-881 2698,-875 2704,-869 2710,-869 2710,-869 2814,-869 2814,-869 2820,-869 2826,-875 2826,-881 2826,-881 2826,-893 2826,-893 2826,-899 2820,-905 2814,-905"/>
+<text text-anchor="middle" x="2762" y="-884.5" font-family="sans" font-size="10.00" fill="#000000">create_header_genome</text>
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+<!-- 4&#45;&gt;9 -->
+<g id="edge18" class="edge">
+<title>4&#45;&gt;9</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2886.829,-1595.616C2847.1776,-1585.2861 2795.2578,-1569.2301 2781,-1553 2754.0187,-1522.2865 2762,-1503.8816 2762,-1463 2762,-1463 2762,-1463 2762,-1031 2762,-990.876 2762,-944.4631 2762,-915.4177"/>
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+</g>
+<!-- 13 -->
+<g id="node14" class="node">
+<title>13</title>
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+<text text-anchor="middle" x="2826" y="-1532.5" font-family="sans" font-size="10.00" fill="#000000">mirna_anno</text>
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+<!-- 4&#45;&gt;13 -->
+<g id="edge23" class="edge">
+<title>4&#45;&gt;13</title>
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+<!-- 14 -->
+<g id="node15" class="node">
+<title>14</title>
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+<text text-anchor="middle" x="2907" y="-1532.5" font-family="sans" font-size="10.00" fill="#000000">dict_chr</text>
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+<!-- 4&#45;&gt;14 -->
+<g id="edge24" class="edge">
+<title>4&#45;&gt;14</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2927.9344,-1588.8314C2924.874,-1580.9617 2921.2221,-1571.5712 2917.8318,-1562.8533"/>
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+</g>
+<!-- 21 -->
+<g id="node22" class="node">
+<title>21</title>
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+<text text-anchor="middle" x="1360" y="-956.5" font-family="sans" font-size="10.00" fill="#000000">create_index_fasta</text>
+</g>
+<!-- 4&#45;&gt;21 -->
+<g id="edge56" class="edge">
+<title>4&#45;&gt;21</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2886.8314,-1597.6806C2838.7623,-1587.5881 2769.1027,-1570.5641 2748,-1553 2713.6269,-1524.3908 2703,-1507.7214 2703,-1463 2703,-1463 2703,-1463 2703,-1103 2703,-1037.7367 1687.1181,-977.0705 1422.4368,-962.3719"/>
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+<!-- 94 -->
+<g id="node95" class="node">
+<title>94</title>
+<path fill="none" stroke="#d89c56" stroke-width="2" stroke-dasharray="5,2" d="M3129.5,-1481C3129.5,-1481 3002.5,-1481 3002.5,-1481 2996.5,-1481 2990.5,-1475 2990.5,-1469 2990.5,-1469 2990.5,-1457 2990.5,-1457 2990.5,-1451 2996.5,-1445 3002.5,-1445 3002.5,-1445 3129.5,-1445 3129.5,-1445 3135.5,-1445 3141.5,-1451 3141.5,-1457 3141.5,-1457 3141.5,-1469 3141.5,-1469 3141.5,-1475 3135.5,-1481 3129.5,-1481"/>
+<text text-anchor="middle" x="3066" y="-1460.5" font-family="sans" font-size="10.00" fill="#000000">mapping_genome_segemehl</text>
+</g>
+<!-- 4&#45;&gt;94 -->
+<g id="edge162" class="edge">
+<title>4&#45;&gt;94</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2951.5912,-1588.7623C2974.6242,-1563.4436 3016.4036,-1517.5182 3042.5973,-1488.7251"/>
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+<!-- 96 -->
+<g id="node97" class="node">
+<title>96</title>
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+<text text-anchor="middle" x="3060" y="-1388.5" font-family="sans" font-size="10.00" fill="#000000">mapping_genome_oligomap</text>
+</g>
+<!-- 4&#45;&gt;96 -->
+<g id="edge167" class="edge">
+<title>4&#45;&gt;96</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2938.6537,-1588.8827C2946.401,-1551.7247 2965.1504,-1468.4127 2982,-1445 2990.5933,-1433.0595 3002.6855,-1422.8775 3014.7889,-1414.6805"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3017.0215,-1417.407 3023.5542,-1409.0658 3013.2457,-1411.5125 3017.0215,-1417.407"/>
+</g>
+<!-- 5 -->
+<g id="node6" class="node">
+<title>5</title>
+<path fill="none" stroke="#56d85b" stroke-width="2" stroke-dasharray="5,2" d="M3615.5,-1625C3615.5,-1625 3554.5,-1625 3554.5,-1625 3548.5,-1625 3542.5,-1619 3542.5,-1613 3542.5,-1613 3542.5,-1601 3542.5,-1601 3542.5,-1595 3548.5,-1589 3554.5,-1589 3554.5,-1589 3615.5,-1589 3615.5,-1589 3621.5,-1589 3627.5,-1595 3627.5,-1601 3627.5,-1601 3627.5,-1613 3627.5,-1613 3627.5,-1619 3621.5,-1625 3615.5,-1625"/>
+<text text-anchor="middle" x="3585" y="-1604.5" font-family="sans" font-size="10.00" fill="#000000">filter_anno_gtf</text>
+</g>
+<!-- 5&#45;&gt;3 -->
+<g id="edge14" class="edge">
+<title>5&#45;&gt;3</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3553.9619,-1588.8314C3538.2295,-1579.6221 3518.9389,-1568.3301 3502.0956,-1558.4706"/>
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+</g>
+<!-- 8 -->
+<g id="node9" class="node">
+<title>8</title>
+<path fill="none" stroke="#5682d8" stroke-width="2" stroke-dasharray="5,2" d="M3728.5,-1265C3728.5,-1265 3669.5,-1265 3669.5,-1265 3663.5,-1265 3657.5,-1259 3657.5,-1253 3657.5,-1253 3657.5,-1241 3657.5,-1241 3657.5,-1235 3663.5,-1229 3669.5,-1229 3669.5,-1229 3728.5,-1229 3728.5,-1229 3734.5,-1229 3740.5,-1235 3740.5,-1241 3740.5,-1241 3740.5,-1253 3740.5,-1253 3740.5,-1259 3734.5,-1265 3728.5,-1265"/>
+<text text-anchor="middle" x="3699" y="-1244.5" font-family="sans" font-size="10.00" fill="#000000">get_exons_gtf</text>
+</g>
+<!-- 5&#45;&gt;8 -->
+<g id="edge17" class="edge">
+<title>5&#45;&gt;8</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3616.0381,-1588.9286C3652.4758,-1565.1156 3708,-1519.5511 3708,-1463 3708,-1463 3708,-1463 3708,-1391 3708,-1350.7977 3704.4625,-1304.4047 3701.8232,-1275.385"/>
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+<!-- 6&#45;&gt;0 -->
+<g id="edge2" class="edge">
+<title>6&#45;&gt;0</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3132.414,-1516.7235C3138.7978,-1506.5841 3146.2204,-1493.5233 3151,-1481 3165.5773,-1442.8056 3170,-1431.8816 3170,-1391 3170,-1391 3170,-1391 3170,-162 3170,-92.0822 3085.4081,-49.4091 3034.8719,-30.1542"/>
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+<!-- 6&#45;&gt;94 -->
+<g id="edge163" class="edge">
+<title>6&#45;&gt;94</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3106.3735,-1516.8314C3100.154,-1508.5386 3092.6678,-1498.557 3085.84,-1489.4533"/>
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+<!-- 7 -->
+<g id="node8" class="node">
+<title>7</title>
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+<text text-anchor="middle" x="3671" y="-1028.5" font-family="sans" font-size="10.00" fill="#000000">gtftobed</text>
+</g>
+<!-- 7&#45;&gt;0 -->
+<g id="edge3" class="edge">
+<title>7&#45;&gt;0</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3668.928,-1012.8427C3665.9989,-985.5621 3661,-932.359 3661,-887 3661,-887 3661,-887 3661,-162 3661,-119.3959 3661.8537,-97.8657 3628,-72 3580.8054,-35.9413 3163.1699,-22.2573 3035.1446,-18.8876"/>
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+<!-- 78 -->
+<g id="node79" class="node">
+<title>78</title>
+<path fill="none" stroke="#56d8a9" stroke-width="2" stroke-dasharray="5,2" d="M3413.5,-977C3413.5,-977 3360.5,-977 3360.5,-977 3354.5,-977 3348.5,-971 3348.5,-965 3348.5,-965 3348.5,-953 3348.5,-953 3348.5,-947 3354.5,-941 3360.5,-941 3360.5,-941 3413.5,-941 3413.5,-941 3419.5,-941 3425.5,-947 3425.5,-953 3425.5,-953 3425.5,-965 3425.5,-965 3425.5,-971 3419.5,-977 3413.5,-977"/>
+<text text-anchor="middle" x="3387" y="-956.5" font-family="sans" font-size="10.00" fill="#000000">trans_to_gen</text>
+</g>
+<!-- 7&#45;&gt;78 -->
+<g id="edge140" class="edge">
+<title>7&#45;&gt;78</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3641.9417,-1023.6331C3593.2967,-1011.3006 3494.8888,-986.3521 3435.5761,-971.3151"/>
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+<!-- 8&#45;&gt;7 -->
+<g id="edge16" class="edge">
+<title>8&#45;&gt;7</title>
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+<!-- 9&#45;&gt;0 -->
+<g id="edge4" class="edge">
+<title>9&#45;&gt;0</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2697.925,-885.289C2290.3102,-874.2004 76,-810.8411 76,-743 76,-743 76,-743 76,-671 76,-569.231 0,-556.769 0,-455 0,-455 0,-455 0,-162 0,-84.134 2614.9822,-26.1093 2960.4784,-18.7828"/>
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+<!-- 76 -->
+<g id="node77" class="node">
+<title>76</title>
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+<text text-anchor="middle" x="3049" y="-812.5" font-family="sans" font-size="10.00" fill="#000000">add_header</text>
+</g>
+<!-- 9&#45;&gt;76 -->
+<g id="edge135" class="edge">
+<title>9&#45;&gt;76</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2826.0512,-870.9314C2879.725,-857.4662 2955.0529,-838.5686 3002.9415,-826.5547"/>
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+</g>
+<!-- 10 -->
+<g id="node11" class="node">
+<title>10</title>
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+<text text-anchor="middle" x="2929" y="-452.5" font-family="sans" font-size="10.00" fill="#000000">gfftobed</text>
+</g>
+<!-- 10&#45;&gt;0 -->
+<g id="edge5" class="edge">
+<title>10&#45;&gt;0</title>
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+<!-- 19 -->
+<g id="node20" class="node">
+<title>19</title>
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+<text text-anchor="middle" x="1526" y="-380.5" font-family="sans" font-size="10.00" fill="#000000">filter_mature_mirs</text>
+</g>
+<!-- 10&#45;&gt;19 -->
+<g id="edge54" class="edge">
+<title>10&#45;&gt;19</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2900.3388,-453.5291C2728.3438,-444.7026 1832.3885,-398.7234 1587.7648,-386.1697"/>
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+<!-- 100 -->
+<g id="node101" class="node">
+<title>100</title>
+<path fill="none" stroke="#bed856" stroke-width="2" stroke-dasharray="5,2" d="M3005.5,-252C3005.5,-252 2940.5,-252 2940.5,-252 2934.5,-252 2928.5,-246 2928.5,-240 2928.5,-240 2928.5,-228 2928.5,-228 2928.5,-222 2934.5,-216 2940.5,-216 2940.5,-216 3005.5,-216 3005.5,-216 3011.5,-216 3017.5,-222 3017.5,-228 3017.5,-228 3017.5,-240 3017.5,-240 3017.5,-246 3011.5,-252 3005.5,-252"/>
+<text text-anchor="middle" x="2973" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">intersect_mirna</text>
+</g>
+<!-- 10&#45;&gt;100 -->
+<g id="edge173" class="edge">
+<title>10&#45;&gt;100</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2932.6007,-436.9146C2940.2743,-398.3723 2958.2832,-307.9185 2967.4413,-261.9197"/>
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+<!-- 11 -->
+<g id="node12" class="node">
+<title>11</title>
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+<text text-anchor="middle" x="2908" y="-812.5" font-family="sans" font-size="10.00" fill="#000000">filter_mir_1_anno</text>
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+<!-- 11&#45;&gt;10 -->
+<g id="edge19" class="edge">
+<title>11&#45;&gt;10</title>
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+<!-- 12 -->
+<g id="node13" class="node">
+<title>12</title>
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+<text text-anchor="middle" x="2888" y="-1460.5" font-family="sans" font-size="10.00" fill="#000000">map_chr_names</text>
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+<!-- 12&#45;&gt;11 -->
+<g id="edge20" class="edge">
+<title>12&#45;&gt;11</title>
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+<!-- 13&#45;&gt;12 -->
+<g id="edge21" class="edge">
+<title>13&#45;&gt;12</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2841.6452,-1516.8314C2848.8591,-1508.454 2857.557,-1498.3531 2865.4605,-1489.1749"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="2868.2711,-1491.2748 2872.1441,-1481.4133 2862.9667,-1486.7071 2868.2711,-1491.2748"/>
+</g>
+<!-- 14&#45;&gt;12 -->
+<g id="edge22" class="edge">
+<title>14&#45;&gt;12</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2902.2055,-1516.8314C2900.1511,-1509.0463 2897.704,-1499.7729 2895.4244,-1491.1347"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="2898.7948,-1490.1892 2892.8591,-1481.4133 2892.0265,-1491.9753 2898.7948,-1490.1892"/>
+</g>
+<!-- 15 -->
+<g id="node16" class="node">
+<title>15</title>
+<path fill="none" stroke="#b6d856" stroke-width="2" stroke-dasharray="5,2" d="M2067.5,-108C2067.5,-108 2010.5,-108 2010.5,-108 2004.5,-108 1998.5,-102 1998.5,-96 1998.5,-96 1998.5,-84 1998.5,-84 1998.5,-78 2004.5,-72 2010.5,-72 2010.5,-72 2067.5,-72 2067.5,-72 2073.5,-72 2079.5,-78 2079.5,-84 2079.5,-84 2079.5,-96 2079.5,-96 2079.5,-102 2073.5,-108 2067.5,-108"/>
+<text text-anchor="middle" x="2039" y="-87.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_final</text>
+</g>
+<!-- 15&#45;&gt;0 -->
+<g id="edge6" class="edge">
+<title>15&#45;&gt;0</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2079.5945,-86.9522C2237.3068,-75.1115 2808.1151,-32.2562 2960.4261,-20.821"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="2960.9479,-24.2917 2970.6578,-20.0528 2960.4238,-17.3114 2960.9479,-24.2917"/>
+</g>
+<!-- 16 -->
+<g id="node17" class="node">
+<title>16</title>
+<path fill="none" stroke="#70d856" stroke-width="2" stroke-dasharray="5,2" d="M1561,-180C1561,-180 1493,-180 1493,-180 1487,-180 1481,-174 1481,-168 1481,-168 1481,-156 1481,-156 1481,-150 1487,-144 1493,-144 1493,-144 1561,-144 1561,-144 1567,-144 1573,-150 1573,-156 1573,-156 1573,-168 1573,-168 1573,-174 1567,-180 1561,-180"/>
+<text text-anchor="middle" x="1527" y="-159.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_concat</text>
+</g>
+<!-- 16&#45;&gt;15 -->
+<g id="edge25" class="edge">
+<title>16&#45;&gt;15</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1573.3396,-155.4835C1669.151,-142.01 1888.401,-111.178 1988.0413,-97.1661"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1988.7446,-100.6017 1998.1597,-95.7432 1987.7697,-93.6699 1988.7446,-100.6017"/>
+</g>
+<!-- 17 -->
+<g id="node18" class="node">
+<title>17</title>
+<path fill="none" stroke="#d8d356" stroke-width="2" stroke-dasharray="5,2" d="M1970,-252C1970,-252 1896,-252 1896,-252 1890,-252 1884,-246 1884,-240 1884,-240 1884,-228 1884,-228 1884,-222 1890,-216 1896,-216 1896,-216 1970,-216 1970,-216 1976,-216 1982,-222 1982,-228 1982,-228 1982,-240 1982,-240 1982,-246 1976,-252 1970,-252"/>
+<text text-anchor="middle" x="1933" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_rename</text>
+</g>
+<!-- 17&#45;&gt;16 -->
+<g id="edge26" class="edge">
+<title>17&#45;&gt;16</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1883.7738,-218.1829C1880.8169,-217.401 1877.8761,-216.6656 1875,-216 1773.301,-192.4631 1652.4641,-176.3021 1583.2526,-168.1477"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1583.3492,-164.6354 1573.0115,-166.9553 1582.5396,-171.5884 1583.3492,-164.6354"/>
+</g>
+<!-- 18 -->
+<g id="node19" class="node">
+<title>18</title>
+<path fill="none" stroke="#d87556" stroke-width="2" stroke-dasharray="5,2" d="M1788.5,-329C1788.5,-329 1753.5,-329 1753.5,-329 1747.5,-329 1741.5,-323 1741.5,-317 1741.5,-317 1741.5,-300 1741.5,-300 1741.5,-294 1747.5,-288 1753.5,-288 1753.5,-288 1788.5,-288 1788.5,-288 1794.5,-288 1800.5,-294 1800.5,-300 1800.5,-300 1800.5,-317 1800.5,-317 1800.5,-323 1794.5,-329 1788.5,-329"/>
+<text text-anchor="middle" x="1771" y="-317" font-family="sans" font-size="10.00" fill="#000000">iso_anno</text>
+<text text-anchor="middle" x="1771" y="-306" font-family="sans" font-size="10.00" fill="#000000">bp_3p: &#45;2</text>
+<text text-anchor="middle" x="1771" y="-295" font-family="sans" font-size="10.00" fill="#000000">bp_5p: &#45;2</text>
+</g>
+<!-- 18&#45;&gt;17 -->
+<g id="edge51" class="edge">
+<title>18&#45;&gt;17</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1800.748,-292.1462C1803.5222,-290.7137 1806.3037,-289.3115 1809,-288 1831.9099,-276.8563 1857.6742,-265.4585 1879.7581,-256.0239"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1881.1428,-259.2385 1888.9782,-252.1071 1878.4058,-252.7957 1881.1428,-259.2385"/>
+</g>
+<!-- 19&#45;&gt;18 -->
+<g id="edge52" class="edge">
+<title>19&#45;&gt;18</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1577.8183,-372.846C1617.8768,-364.2303 1674.6179,-350.3563 1731.5725,-328.767"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1733.0189,-331.9603 1741.0836,-325.0892 1730.4943,-325.4314 1733.0189,-331.9603"/>
+</g>
+<!-- 23 -->
+<g id="node24" class="node">
+<title>23</title>
+<path fill="none" stroke="#d87556" stroke-width="2" stroke-dasharray="5,2" d="M1865.5,-329C1865.5,-329 1830.5,-329 1830.5,-329 1824.5,-329 1818.5,-323 1818.5,-317 1818.5,-317 1818.5,-300 1818.5,-300 1818.5,-294 1824.5,-288 1830.5,-288 1830.5,-288 1865.5,-288 1865.5,-288 1871.5,-288 1877.5,-294 1877.5,-300 1877.5,-300 1877.5,-317 1877.5,-317 1877.5,-323 1871.5,-329 1865.5,-329"/>
+<text text-anchor="middle" x="1848" y="-317" font-family="sans" font-size="10.00" fill="#000000">iso_anno</text>
+<text text-anchor="middle" x="1848" y="-306" font-family="sans" font-size="10.00" fill="#000000">bp_3p: &#45;2</text>
+<text text-anchor="middle" x="1848" y="-295" font-family="sans" font-size="10.00" fill="#000000">bp_5p: &#45;1</text>
+</g>
+<!-- 19&#45;&gt;23 -->
+<g id="edge58" class="edge">
+<title>19&#45;&gt;23</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1577.5374,-377.7972C1633.1006,-371.1725 1723.8815,-357.3973 1808.6562,-328.6052"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1809.8645,-331.8907 1818.1626,-325.3035 1807.5678,-325.2782 1809.8645,-331.8907"/>
+</g>
+<!-- 25 -->
+<g id="node26" class="node">
+<title>25</title>
+<path fill="none" stroke="#d87556" stroke-width="2" stroke-dasharray="5,2" d="M1942.5,-329C1942.5,-329 1907.5,-329 1907.5,-329 1901.5,-329 1895.5,-323 1895.5,-317 1895.5,-317 1895.5,-300 1895.5,-300 1895.5,-294 1901.5,-288 1907.5,-288 1907.5,-288 1942.5,-288 1942.5,-288 1948.5,-288 1954.5,-294 1954.5,-300 1954.5,-300 1954.5,-317 1954.5,-317 1954.5,-323 1948.5,-329 1942.5,-329"/>
+<text text-anchor="middle" x="1925" y="-317" font-family="sans" font-size="10.00" fill="#000000">iso_anno</text>
+<text text-anchor="middle" x="1925" y="-306" font-family="sans" font-size="10.00" fill="#000000">bp_3p: &#45;2</text>
+<text text-anchor="middle" x="1925" y="-295" font-family="sans" font-size="10.00" fill="#000000">bp_5p: 0</text>
+</g>
+<!-- 19&#45;&gt;25 -->
+<g id="edge61" class="edge">
+<title>19&#45;&gt;25</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1577.6191,-380.6722C1646.6511,-376.3868 1772.4591,-364.4604 1885.3676,-328.6247"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1886.7754,-331.8475 1895.2054,-325.43 1884.6133,-325.1898 1886.7754,-331.8475"/>
+</g>
+<!-- 27 -->
+<g id="node28" class="node">
+<title>27</title>
+<path fill="none" stroke="#d87556" stroke-width="2" stroke-dasharray="5,2" d="M2019.5,-329C2019.5,-329 1984.5,-329 1984.5,-329 1978.5,-329 1972.5,-323 1972.5,-317 1972.5,-317 1972.5,-300 1972.5,-300 1972.5,-294 1978.5,-288 1984.5,-288 1984.5,-288 2019.5,-288 2019.5,-288 2025.5,-288 2031.5,-294 2031.5,-300 2031.5,-300 2031.5,-317 2031.5,-317 2031.5,-323 2025.5,-329 2019.5,-329"/>
+<text text-anchor="middle" x="2002" y="-317" font-family="sans" font-size="10.00" fill="#000000">iso_anno</text>
+<text text-anchor="middle" x="2002" y="-306" font-family="sans" font-size="10.00" fill="#000000">bp_3p: &#45;2</text>
+<text text-anchor="middle" x="2002" y="-295" font-family="sans" font-size="10.00" fill="#000000">bp_5p: 1</text>
+</g>
+<!-- 19&#45;&gt;27 -->
+<g id="edge64" class="edge">
+<title>19&#45;&gt;27</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1577.6439,-378.9626C1673.4184,-371.1052 1875.9403,-352.663 1962.5085,-328.4198"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1963.6534,-331.7307 1972.2321,-325.5132 1961.6485,-325.0239 1963.6534,-331.7307"/>
+</g>
+<!-- 29 -->
+<g id="node30" class="node">
+<title>29</title>
+<path fill="none" stroke="#d87556" stroke-width="2" stroke-dasharray="5,2" d="M2096.5,-329C2096.5,-329 2061.5,-329 2061.5,-329 2055.5,-329 2049.5,-323 2049.5,-317 2049.5,-317 2049.5,-300 2049.5,-300 2049.5,-294 2055.5,-288 2061.5,-288 2061.5,-288 2096.5,-288 2096.5,-288 2102.5,-288 2108.5,-294 2108.5,-300 2108.5,-300 2108.5,-317 2108.5,-317 2108.5,-323 2102.5,-329 2096.5,-329"/>
+<text text-anchor="middle" x="2079" y="-317" font-family="sans" font-size="10.00" fill="#000000">iso_anno</text>
+<text text-anchor="middle" x="2079" y="-306" font-family="sans" font-size="10.00" fill="#000000">bp_3p: &#45;2</text>
+<text text-anchor="middle" x="2079" y="-295" font-family="sans" font-size="10.00" fill="#000000">bp_5p: 2</text>
+</g>
+<!-- 19&#45;&gt;29 -->
+<g id="edge67" class="edge">
+<title>19&#45;&gt;29</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1577.5425,-380.064C1686.4122,-373.4741 1937.4677,-356.1301 2039.5578,-328.3789"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="2040.6185,-331.7156 2049.2502,-325.572 2038.6712,-324.9919 2040.6185,-331.7156"/>
+</g>
+<!-- 31 -->
+<g id="node32" class="node">
+<title>31</title>
+<path fill="none" stroke="#d87556" stroke-width="2" stroke-dasharray="5,2" d="M2173.5,-329C2173.5,-329 2138.5,-329 2138.5,-329 2132.5,-329 2126.5,-323 2126.5,-317 2126.5,-317 2126.5,-300 2126.5,-300 2126.5,-294 2132.5,-288 2138.5,-288 2138.5,-288 2173.5,-288 2173.5,-288 2179.5,-288 2185.5,-294 2185.5,-300 2185.5,-300 2185.5,-317 2185.5,-317 2185.5,-323 2179.5,-329 2173.5,-329"/>
+<text text-anchor="middle" x="2156" y="-317" font-family="sans" font-size="10.00" fill="#000000">iso_anno</text>
+<text text-anchor="middle" x="2156" y="-306" font-family="sans" font-size="10.00" fill="#000000">bp_3p: &#45;1</text>
+<text text-anchor="middle" x="2156" y="-295" font-family="sans" font-size="10.00" fill="#000000">bp_5p: &#45;2</text>
+</g>
+<!-- 19&#45;&gt;31 -->
+<g id="edge70" class="edge">
+<title>19&#45;&gt;31</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1577.6883,-380.8693C1698.7839,-375.4738 1998.8272,-359.6605 2116.4523,-328.3895"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="2117.5927,-331.7044 2126.2633,-325.6157 2115.6882,-324.9684 2117.5927,-331.7044"/>
+</g>
+<!-- 33 -->
+<g id="node34" class="node">
+<title>33</title>
+<path fill="none" stroke="#d87556" stroke-width="2" stroke-dasharray="5,2" d="M2250.5,-329C2250.5,-329 2215.5,-329 2215.5,-329 2209.5,-329 2203.5,-323 2203.5,-317 2203.5,-317 2203.5,-300 2203.5,-300 2203.5,-294 2209.5,-288 2215.5,-288 2215.5,-288 2250.5,-288 2250.5,-288 2256.5,-288 2262.5,-294 2262.5,-300 2262.5,-300 2262.5,-317 2262.5,-317 2262.5,-323 2256.5,-329 2250.5,-329"/>
+<text text-anchor="middle" x="2233" y="-317" font-family="sans" font-size="10.00" fill="#000000">iso_anno</text>
+<text text-anchor="middle" x="2233" y="-306" font-family="sans" font-size="10.00" fill="#000000">bp_3p: &#45;1</text>
+<text text-anchor="middle" x="2233" y="-295" font-family="sans" font-size="10.00" fill="#000000">bp_5p: &#45;1</text>
+</g>
+<!-- 19&#45;&gt;33 -->
+<g id="edge73" class="edge">
+<title>19&#45;&gt;33</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1577.8314,-381.4935C1710.3996,-377.2244 2060.1147,-363.241 2193.3115,-328.4141"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="2194.5733,-331.6963 2203.2732,-325.6495 2192.7014,-324.9512 2194.5733,-331.6963"/>
+</g>
+<!-- 35 -->
+<g id="node36" class="node">
+<title>35</title>
+<path fill="none" stroke="#d87556" stroke-width="2" stroke-dasharray="5,2" d="M2327.5,-329C2327.5,-329 2292.5,-329 2292.5,-329 2286.5,-329 2280.5,-323 2280.5,-317 2280.5,-317 2280.5,-300 2280.5,-300 2280.5,-294 2286.5,-288 2292.5,-288 2292.5,-288 2327.5,-288 2327.5,-288 2333.5,-288 2339.5,-294 2339.5,-300 2339.5,-300 2339.5,-317 2339.5,-317 2339.5,-323 2333.5,-329 2327.5,-329"/>
+<text text-anchor="middle" x="2310" y="-317" font-family="sans" font-size="10.00" fill="#000000">iso_anno</text>
+<text text-anchor="middle" x="2310" y="-306" font-family="sans" font-size="10.00" fill="#000000">bp_3p: &#45;1</text>
+<text text-anchor="middle" x="2310" y="-295" font-family="sans" font-size="10.00" fill="#000000">bp_5p: 0</text>
+</g>
+<!-- 19&#45;&gt;35 -->
+<g id="edge76" class="edge">
+<title>19&#45;&gt;35</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1577.6197,-382C1720.8266,-378.8027 2121.7439,-366.8738 2270.437,-328.3726"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="2271.5607,-331.6938 2280.2809,-325.6764 2269.7115,-324.9425 2271.5607,-331.6938"/>
+</g>
+<!-- 37 -->
+<g id="node38" class="node">
+<title>37</title>
+<path fill="none" stroke="#d87556" stroke-width="2" stroke-dasharray="5,2" d="M2404.5,-329C2404.5,-329 2369.5,-329 2369.5,-329 2363.5,-329 2357.5,-323 2357.5,-317 2357.5,-317 2357.5,-300 2357.5,-300 2357.5,-294 2363.5,-288 2369.5,-288 2369.5,-288 2404.5,-288 2404.5,-288 2410.5,-288 2416.5,-294 2416.5,-300 2416.5,-300 2416.5,-317 2416.5,-317 2416.5,-323 2410.5,-329 2404.5,-329"/>
+<text text-anchor="middle" x="2387" y="-317" font-family="sans" font-size="10.00" fill="#000000">iso_anno</text>
+<text text-anchor="middle" x="2387" y="-306" font-family="sans" font-size="10.00" fill="#000000">bp_3p: &#45;1</text>
+<text text-anchor="middle" x="2387" y="-295" font-family="sans" font-size="10.00" fill="#000000">bp_5p: 1</text>
+</g>
+<!-- 19&#45;&gt;37 -->
+<g id="edge79" class="edge">
+<title>19&#45;&gt;37</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1577.57,-382.408C1730.9127,-380.2179 2183.0271,-370.5412 2347.3496,-328.3889"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="2348.5494,-331.6901 2357.2871,-325.6983 2346.7199,-324.9334 2348.5494,-331.6901"/>
+</g>
+<!-- 39 -->
+<g id="node40" class="node">
+<title>39</title>
+<path fill="none" stroke="#d87556" stroke-width="2" stroke-dasharray="5,2" d="M574.5,-329C574.5,-329 539.5,-329 539.5,-329 533.5,-329 527.5,-323 527.5,-317 527.5,-317 527.5,-300 527.5,-300 527.5,-294 533.5,-288 539.5,-288 539.5,-288 574.5,-288 574.5,-288 580.5,-288 586.5,-294 586.5,-300 586.5,-300 586.5,-317 586.5,-317 586.5,-323 580.5,-329 574.5,-329"/>
+<text text-anchor="middle" x="557" y="-317" font-family="sans" font-size="10.00" fill="#000000">iso_anno</text>
+<text text-anchor="middle" x="557" y="-306" font-family="sans" font-size="10.00" fill="#000000">bp_3p: &#45;1</text>
+<text text-anchor="middle" x="557" y="-295" font-family="sans" font-size="10.00" fill="#000000">bp_5p: 2</text>
+</g>
+<!-- 19&#45;&gt;39 -->
+<g id="edge82" class="edge">
+<title>19&#45;&gt;39</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1474.2888,-368.5771C1467.8336,-367.1658 1461.2914,-365.9191 1455,-365 1268.8727,-337.8088 795.5007,-378.316 596.5978,-328.7257"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="597.3232,-325.2975 586.7616,-326.1364 595.5411,-332.0669 597.3232,-325.2975"/>
+</g>
+<!-- 41 -->
+<g id="node42" class="node">
+<title>41</title>
+<path fill="none" stroke="#d87556" stroke-width="2" stroke-dasharray="5,2" d="M651.5,-329C651.5,-329 616.5,-329 616.5,-329 610.5,-329 604.5,-323 604.5,-317 604.5,-317 604.5,-300 604.5,-300 604.5,-294 610.5,-288 616.5,-288 616.5,-288 651.5,-288 651.5,-288 657.5,-288 663.5,-294 663.5,-300 663.5,-300 663.5,-317 663.5,-317 663.5,-323 657.5,-329 651.5,-329"/>
+<text text-anchor="middle" x="634" y="-317" font-family="sans" font-size="10.00" fill="#000000">iso_anno</text>
+<text text-anchor="middle" x="634" y="-306" font-family="sans" font-size="10.00" fill="#000000">bp_3p: 0</text>
+<text text-anchor="middle" x="634" y="-295" font-family="sans" font-size="10.00" fill="#000000">bp_5p: &#45;2</text>
+</g>
+<!-- 19&#45;&gt;41 -->
+<g id="edge85" class="edge">
+<title>19&#45;&gt;41</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1474.2851,-368.6022C1467.8306,-367.1866 1461.2895,-365.932 1455,-365 1285.8106,-339.9282 855.7705,-374.2341 673.5671,-328.7184"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="674.3277,-325.2992 663.765,-326.1241 672.5366,-332.0662 674.3277,-325.2992"/>
+</g>
+<!-- 43 -->
+<g id="node44" class="node">
+<title>43</title>
+<path fill="none" stroke="#d87556" stroke-width="2" stroke-dasharray="5,2" d="M728.5,-329C728.5,-329 693.5,-329 693.5,-329 687.5,-329 681.5,-323 681.5,-317 681.5,-317 681.5,-300 681.5,-300 681.5,-294 687.5,-288 693.5,-288 693.5,-288 728.5,-288 728.5,-288 734.5,-288 740.5,-294 740.5,-300 740.5,-300 740.5,-317 740.5,-317 740.5,-323 734.5,-329 728.5,-329"/>
+<text text-anchor="middle" x="711" y="-317" font-family="sans" font-size="10.00" fill="#000000">iso_anno</text>
+<text text-anchor="middle" x="711" y="-306" font-family="sans" font-size="10.00" fill="#000000">bp_3p: 0</text>
+<text text-anchor="middle" x="711" y="-295" font-family="sans" font-size="10.00" fill="#000000">bp_5p: &#45;1</text>
+</g>
+<!-- 19&#45;&gt;43 -->
+<g id="edge88" class="edge">
+<title>19&#45;&gt;43</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1474.2805,-368.6328C1467.8268,-367.2119 1461.2871,-365.9478 1455,-365 1302.848,-342.0638 916.5601,-370.1331 750.8814,-328.7979"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="751.3328,-325.2964 740.7691,-326.1092 749.534,-332.0613 751.3328,-325.2964"/>
+</g>
+<!-- 45 -->
+<g id="node46" class="node">
+<title>45</title>
+<path fill="none" stroke="#d87556" stroke-width="2" stroke-dasharray="5,2" d="M803.5,-329C803.5,-329 770.5,-329 770.5,-329 764.5,-329 758.5,-323 758.5,-317 758.5,-317 758.5,-300 758.5,-300 758.5,-294 764.5,-288 770.5,-288 770.5,-288 803.5,-288 803.5,-288 809.5,-288 815.5,-294 815.5,-300 815.5,-300 815.5,-317 815.5,-317 815.5,-323 809.5,-329 803.5,-329"/>
+<text text-anchor="middle" x="787" y="-317" font-family="sans" font-size="10.00" fill="#000000">iso_anno</text>
+<text text-anchor="middle" x="787" y="-306" font-family="sans" font-size="10.00" fill="#000000">bp_3p: 0</text>
+<text text-anchor="middle" x="787" y="-295" font-family="sans" font-size="10.00" fill="#000000">bp_5p: 0</text>
+</g>
+<!-- 19&#45;&gt;45 -->
+<g id="edge91" class="edge">
+<title>19&#45;&gt;45</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1474.2749,-368.6697C1467.8221,-367.2425 1461.2842,-365.9667 1455,-365 1180.619,-322.7901 1095.8306,-405.0568 825.2499,-328.6961"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="826.123,-325.3054 815.5455,-325.9123 824.1928,-332.0341 826.123,-325.3054"/>
+</g>
+<!-- 47 -->
+<g id="node48" class="node">
+<title>47</title>
+<path fill="none" stroke="#d87556" stroke-width="2" stroke-dasharray="5,2" d="M878.5,-329C878.5,-329 845.5,-329 845.5,-329 839.5,-329 833.5,-323 833.5,-317 833.5,-317 833.5,-300 833.5,-300 833.5,-294 839.5,-288 845.5,-288 845.5,-288 878.5,-288 878.5,-288 884.5,-288 890.5,-294 890.5,-300 890.5,-300 890.5,-317 890.5,-317 890.5,-323 884.5,-329 878.5,-329"/>
+<text text-anchor="middle" x="862" y="-317" font-family="sans" font-size="10.00" fill="#000000">iso_anno</text>
+<text text-anchor="middle" x="862" y="-306" font-family="sans" font-size="10.00" fill="#000000">bp_3p: 0</text>
+<text text-anchor="middle" x="862" y="-295" font-family="sans" font-size="10.00" fill="#000000">bp_5p: 1</text>
+</g>
+<!-- 19&#45;&gt;47 -->
+<g id="edge94" class="edge">
+<title>19&#45;&gt;47</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1474.2676,-368.7165C1467.8161,-367.2813 1461.2805,-365.9908 1455,-365 1213.6215,-326.9193 1138.5935,-396.8082 900.1953,-328.6937"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="901.1319,-325.3211 890.5523,-325.8892 899.177,-332.0426 901.1319,-325.3211"/>
+</g>
+<!-- 49 -->
+<g id="node50" class="node">
+<title>49</title>
+<path fill="none" stroke="#d87556" stroke-width="2" stroke-dasharray="5,2" d="M953.5,-329C953.5,-329 920.5,-329 920.5,-329 914.5,-329 908.5,-323 908.5,-317 908.5,-317 908.5,-300 908.5,-300 908.5,-294 914.5,-288 920.5,-288 920.5,-288 953.5,-288 953.5,-288 959.5,-288 965.5,-294 965.5,-300 965.5,-300 965.5,-317 965.5,-317 965.5,-323 959.5,-329 953.5,-329"/>
+<text text-anchor="middle" x="937" y="-317" font-family="sans" font-size="10.00" fill="#000000">iso_anno</text>
+<text text-anchor="middle" x="937" y="-306" font-family="sans" font-size="10.00" fill="#000000">bp_3p: 0</text>
+<text text-anchor="middle" x="937" y="-295" font-family="sans" font-size="10.00" fill="#000000">bp_5p: 2</text>
+</g>
+<!-- 19&#45;&gt;49 -->
+<g id="edge97" class="edge">
+<title>19&#45;&gt;49</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1474.2578,-368.7777C1467.808,-367.332 1461.2754,-366.0224 1455,-365 1246.6166,-331.051 1181.3757,-388.5786 975.1699,-328.7037"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="976.1434,-325.3418 965.5612,-325.859 974.1562,-332.0538 976.1434,-325.3418"/>
+</g>
+<!-- 51 -->
+<g id="node52" class="node">
+<title>51</title>
+<path fill="none" stroke="#d87556" stroke-width="2" stroke-dasharray="5,2" d="M1030.5,-329C1030.5,-329 995.5,-329 995.5,-329 989.5,-329 983.5,-323 983.5,-317 983.5,-317 983.5,-300 983.5,-300 983.5,-294 989.5,-288 995.5,-288 995.5,-288 1030.5,-288 1030.5,-288 1036.5,-288 1042.5,-294 1042.5,-300 1042.5,-300 1042.5,-317 1042.5,-317 1042.5,-323 1036.5,-329 1030.5,-329"/>
+<text text-anchor="middle" x="1013" y="-317" font-family="sans" font-size="10.00" fill="#000000">iso_anno</text>
+<text text-anchor="middle" x="1013" y="-306" font-family="sans" font-size="10.00" fill="#000000">bp_3p: 1</text>
+<text text-anchor="middle" x="1013" y="-295" font-family="sans" font-size="10.00" fill="#000000">bp_5p: &#45;2</text>
+</g>
+<!-- 19&#45;&gt;51 -->
+<g id="edge100" class="edge">
+<title>19&#45;&gt;51</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1474.2434,-368.8641C1467.7961,-367.4035 1461.268,-366.0668 1455,-365 1280.4991,-335.3004 1225.6254,-379.2176 1052.4805,-328.872"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1053.3846,-325.4895 1042.8019,-325.9963 1051.3909,-332.1996 1053.3846,-325.4895"/>
+</g>
+<!-- 53 -->
+<g id="node54" class="node">
+<title>53</title>
+<path fill="none" stroke="#d87556" stroke-width="2" stroke-dasharray="5,2" d="M1107.5,-329C1107.5,-329 1072.5,-329 1072.5,-329 1066.5,-329 1060.5,-323 1060.5,-317 1060.5,-317 1060.5,-300 1060.5,-300 1060.5,-294 1066.5,-288 1072.5,-288 1072.5,-288 1107.5,-288 1107.5,-288 1113.5,-288 1119.5,-294 1119.5,-300 1119.5,-300 1119.5,-317 1119.5,-317 1119.5,-323 1113.5,-329 1107.5,-329"/>
+<text text-anchor="middle" x="1090" y="-317" font-family="sans" font-size="10.00" fill="#000000">iso_anno</text>
+<text text-anchor="middle" x="1090" y="-306" font-family="sans" font-size="10.00" fill="#000000">bp_3p: 1</text>
+<text text-anchor="middle" x="1090" y="-295" font-family="sans" font-size="10.00" fill="#000000">bp_5p: &#45;1</text>
+</g>
+<!-- 19&#45;&gt;53 -->
+<g id="edge103" class="edge">
+<title>19&#45;&gt;53</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1474.2212,-368.9904C1467.7777,-367.5082 1461.2566,-366.1319 1455,-365 1314.3555,-339.5566 1269.5926,-371.0372 1129.6221,-328.9538"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1130.408,-325.5336 1119.8207,-325.9348 1128.3474,-332.2234 1130.408,-325.5336"/>
+</g>
+<!-- 55 -->
+<g id="node56" class="node">
+<title>55</title>
+<path fill="none" stroke="#d87556" stroke-width="2" stroke-dasharray="5,2" d="M1182.5,-329C1182.5,-329 1149.5,-329 1149.5,-329 1143.5,-329 1137.5,-323 1137.5,-317 1137.5,-317 1137.5,-300 1137.5,-300 1137.5,-294 1143.5,-288 1149.5,-288 1149.5,-288 1182.5,-288 1182.5,-288 1188.5,-288 1194.5,-294 1194.5,-300 1194.5,-300 1194.5,-317 1194.5,-317 1194.5,-323 1188.5,-329 1182.5,-329"/>
+<text text-anchor="middle" x="1166" y="-317" font-family="sans" font-size="10.00" fill="#000000">iso_anno</text>
+<text text-anchor="middle" x="1166" y="-306" font-family="sans" font-size="10.00" fill="#000000">bp_3p: 1</text>
+<text text-anchor="middle" x="1166" y="-295" font-family="sans" font-size="10.00" fill="#000000">bp_5p: 0</text>
+</g>
+<!-- 19&#45;&gt;55 -->
+<g id="edge106" class="edge">
+<title>19&#45;&gt;55</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1474.1842,-369.1861C1467.747,-367.6703 1461.2376,-366.2326 1455,-365 1347.1525,-343.6886 1312.2272,-363.8026 1204.2554,-328.8564"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1205.2184,-325.4883 1194.6249,-325.6581 1203.0121,-332.1315 1205.2184,-325.4883"/>
+</g>
+<!-- 57 -->
+<g id="node58" class="node">
+<title>57</title>
+<path fill="none" stroke="#d87556" stroke-width="2" stroke-dasharray="5,2" d="M1257.5,-329C1257.5,-329 1224.5,-329 1224.5,-329 1218.5,-329 1212.5,-323 1212.5,-317 1212.5,-317 1212.5,-300 1212.5,-300 1212.5,-294 1218.5,-288 1224.5,-288 1224.5,-288 1257.5,-288 1257.5,-288 1263.5,-288 1269.5,-294 1269.5,-300 1269.5,-300 1269.5,-317 1269.5,-317 1269.5,-323 1263.5,-329 1257.5,-329"/>
+<text text-anchor="middle" x="1241" y="-317" font-family="sans" font-size="10.00" fill="#000000">iso_anno</text>
+<text text-anchor="middle" x="1241" y="-306" font-family="sans" font-size="10.00" fill="#000000">bp_3p: 1</text>
+<text text-anchor="middle" x="1241" y="-295" font-family="sans" font-size="10.00" fill="#000000">bp_5p: 1</text>
+</g>
+<!-- 19&#45;&gt;57 -->
+<g id="edge109" class="edge">
+<title>19&#45;&gt;57</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1474.494,-369.6356C1467.9439,-368.0264 1461.3226,-366.4436 1455,-365 1379.7939,-347.829 1355.2322,-356.0642 1279.2181,-328.9679"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1280.28,-325.6296 1269.6861,-325.4843 1277.8771,-332.2043 1280.28,-325.6296"/>
+</g>
+<!-- 59 -->
+<g id="node60" class="node">
+<title>59</title>
+<path fill="none" stroke="#d87556" stroke-width="2" stroke-dasharray="5,2" d="M1332.5,-329C1332.5,-329 1299.5,-329 1299.5,-329 1293.5,-329 1287.5,-323 1287.5,-317 1287.5,-317 1287.5,-300 1287.5,-300 1287.5,-294 1293.5,-288 1299.5,-288 1299.5,-288 1332.5,-288 1332.5,-288 1338.5,-288 1344.5,-294 1344.5,-300 1344.5,-300 1344.5,-317 1344.5,-317 1344.5,-323 1338.5,-329 1332.5,-329"/>
+<text text-anchor="middle" x="1316" y="-317" font-family="sans" font-size="10.00" fill="#000000">iso_anno</text>
+<text text-anchor="middle" x="1316" y="-306" font-family="sans" font-size="10.00" fill="#000000">bp_3p: 1</text>
+<text text-anchor="middle" x="1316" y="-295" font-family="sans" font-size="10.00" fill="#000000">bp_5p: 2</text>
+</g>
+<!-- 19&#45;&gt;59 -->
+<g id="edge112" class="edge">
+<title>19&#45;&gt;59</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1474.2984,-369.8337C1441.6403,-360.847 1398.6094,-347.7753 1354.0359,-329.1224"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1355.3759,-325.889 1344.8043,-325.1873 1352.631,-332.3284 1355.3759,-325.889"/>
+</g>
+<!-- 61 -->
+<g id="node62" class="node">
+<title>61</title>
+<path fill="none" stroke="#d87556" stroke-width="2" stroke-dasharray="5,2" d="M1409.5,-329C1409.5,-329 1374.5,-329 1374.5,-329 1368.5,-329 1362.5,-323 1362.5,-317 1362.5,-317 1362.5,-300 1362.5,-300 1362.5,-294 1368.5,-288 1374.5,-288 1374.5,-288 1409.5,-288 1409.5,-288 1415.5,-288 1421.5,-294 1421.5,-300 1421.5,-300 1421.5,-317 1421.5,-317 1421.5,-323 1415.5,-329 1409.5,-329"/>
+<text text-anchor="middle" x="1392" y="-317" font-family="sans" font-size="10.00" fill="#000000">iso_anno</text>
+<text text-anchor="middle" x="1392" y="-306" font-family="sans" font-size="10.00" fill="#000000">bp_3p: 2</text>
+<text text-anchor="middle" x="1392" y="-295" font-family="sans" font-size="10.00" fill="#000000">bp_5p: &#45;2</text>
+</g>
+<!-- 19&#45;&gt;61 -->
+<g id="edge115" class="edge">
+<title>19&#45;&gt;61</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1493.5623,-364.9656C1474.6206,-354.4346 1450.6037,-341.0819 1430.6809,-330.0054"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1432.289,-326.8949 1421.8482,-325.0947 1428.8875,-333.013 1432.289,-326.8949"/>
+</g>
+<!-- 63 -->
+<g id="node64" class="node">
+<title>63</title>
+<path fill="none" stroke="#d87556" stroke-width="2" stroke-dasharray="5,2" d="M1486.5,-329C1486.5,-329 1451.5,-329 1451.5,-329 1445.5,-329 1439.5,-323 1439.5,-317 1439.5,-317 1439.5,-300 1439.5,-300 1439.5,-294 1445.5,-288 1451.5,-288 1451.5,-288 1486.5,-288 1486.5,-288 1492.5,-288 1498.5,-294 1498.5,-300 1498.5,-300 1498.5,-317 1498.5,-317 1498.5,-323 1492.5,-329 1486.5,-329"/>
+<text text-anchor="middle" x="1469" y="-317" font-family="sans" font-size="10.00" fill="#000000">iso_anno</text>
+<text text-anchor="middle" x="1469" y="-306" font-family="sans" font-size="10.00" fill="#000000">bp_3p: 2</text>
+<text text-anchor="middle" x="1469" y="-295" font-family="sans" font-size="10.00" fill="#000000">bp_5p: &#45;1</text>
+</g>
+<!-- 19&#45;&gt;63 -->
+<g id="edge118" class="edge">
+<title>19&#45;&gt;63</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1512.2019,-364.9656C1505.8311,-356.6389 1498.1106,-346.5481 1490.9686,-337.2133"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1493.7458,-335.0832 1484.8895,-329.2679 1488.1863,-339.3367 1493.7458,-335.0832"/>
+</g>
+<!-- 65 -->
+<g id="node66" class="node">
+<title>65</title>
+<path fill="none" stroke="#d87556" stroke-width="2" stroke-dasharray="5,2" d="M1561.5,-329C1561.5,-329 1528.5,-329 1528.5,-329 1522.5,-329 1516.5,-323 1516.5,-317 1516.5,-317 1516.5,-300 1516.5,-300 1516.5,-294 1522.5,-288 1528.5,-288 1528.5,-288 1561.5,-288 1561.5,-288 1567.5,-288 1573.5,-294 1573.5,-300 1573.5,-300 1573.5,-317 1573.5,-317 1573.5,-323 1567.5,-329 1561.5,-329"/>
+<text text-anchor="middle" x="1545" y="-317" font-family="sans" font-size="10.00" fill="#000000">iso_anno</text>
+<text text-anchor="middle" x="1545" y="-306" font-family="sans" font-size="10.00" fill="#000000">bp_3p: 2</text>
+<text text-anchor="middle" x="1545" y="-295" font-family="sans" font-size="10.00" fill="#000000">bp_5p: 0</text>
+</g>
+<!-- 19&#45;&gt;65 -->
+<g id="edge121" class="edge">
+<title>19&#45;&gt;65</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1530.5994,-364.9656C1532.5728,-357.2277 1534.9348,-347.9663 1537.1695,-339.2038"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1540.6236,-339.8227 1539.7035,-329.2679 1533.8407,-338.0928 1540.6236,-339.8227"/>
+</g>
+<!-- 67 -->
+<g id="node68" class="node">
+<title>67</title>
+<path fill="none" stroke="#d87556" stroke-width="2" stroke-dasharray="5,2" d="M1636.5,-329C1636.5,-329 1603.5,-329 1603.5,-329 1597.5,-329 1591.5,-323 1591.5,-317 1591.5,-317 1591.5,-300 1591.5,-300 1591.5,-294 1597.5,-288 1603.5,-288 1603.5,-288 1636.5,-288 1636.5,-288 1642.5,-288 1648.5,-294 1648.5,-300 1648.5,-300 1648.5,-317 1648.5,-317 1648.5,-323 1642.5,-329 1636.5,-329"/>
+<text text-anchor="middle" x="1620" y="-317" font-family="sans" font-size="10.00" fill="#000000">iso_anno</text>
+<text text-anchor="middle" x="1620" y="-306" font-family="sans" font-size="10.00" fill="#000000">bp_3p: 2</text>
+<text text-anchor="middle" x="1620" y="-295" font-family="sans" font-size="10.00" fill="#000000">bp_5p: 1</text>
+</g>
+<!-- 19&#45;&gt;67 -->
+<g id="edge124" class="edge">
+<title>19&#45;&gt;67</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1548.7548,-364.9656C1559.8977,-356.1343 1573.5444,-345.3185 1585.9014,-335.5249"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1588.1331,-338.2222 1593.7962,-329.2679 1583.7852,-332.7362 1588.1331,-338.2222"/>
+</g>
+<!-- 69 -->
+<g id="node70" class="node">
+<title>69</title>
+<path fill="none" stroke="#d87556" stroke-width="2" stroke-dasharray="5,2" d="M1711.5,-329C1711.5,-329 1678.5,-329 1678.5,-329 1672.5,-329 1666.5,-323 1666.5,-317 1666.5,-317 1666.5,-300 1666.5,-300 1666.5,-294 1672.5,-288 1678.5,-288 1678.5,-288 1711.5,-288 1711.5,-288 1717.5,-288 1723.5,-294 1723.5,-300 1723.5,-300 1723.5,-317 1723.5,-317 1723.5,-323 1717.5,-329 1711.5,-329"/>
+<text text-anchor="middle" x="1695" y="-317" font-family="sans" font-size="10.00" fill="#000000">iso_anno</text>
+<text text-anchor="middle" x="1695" y="-306" font-family="sans" font-size="10.00" fill="#000000">bp_3p: 2</text>
+<text text-anchor="middle" x="1695" y="-295" font-family="sans" font-size="10.00" fill="#000000">bp_5p: 2</text>
+</g>
+<!-- 19&#45;&gt;69 -->
+<g id="edge127" class="edge">
+<title>19&#45;&gt;69</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1573.1989,-364.9179C1598.3522,-354.9384 1629.6615,-341.966 1657,-329 1657.0931,-328.9558 1657.1863,-328.9115 1657.2797,-328.8671"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1658.7111,-332.0641 1666.1129,-324.4836 1655.5994,-325.7938 1658.7111,-332.0641"/>
+</g>
+<!-- 20 -->
+<g id="node21" class="node">
+<title>20</title>
+<path fill="none" stroke="#56d863" stroke-width="2" stroke-dasharray="5,2" d="M1434,-401C1434,-401 1370,-401 1370,-401 1364,-401 1358,-395 1358,-389 1358,-389 1358,-377 1358,-377 1358,-371 1364,-365 1370,-365 1370,-365 1434,-365 1434,-365 1440,-365 1446,-371 1446,-377 1446,-377 1446,-389 1446,-389 1446,-395 1440,-401 1434,-401"/>
+<text text-anchor="middle" x="1402" y="-380.5" font-family="sans" font-size="10.00" fill="#000000">extract_chr_len</text>
+</g>
+<!-- 20&#45;&gt;18 -->
+<g id="edge53" class="edge">
+<title>20&#45;&gt;18</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1446.2001,-369.5041C1452.4757,-367.8419 1458.8761,-366.2807 1465,-365 1579.1145,-341.1349 1615.9896,-364.1323 1731.6479,-328.5033"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1732.7406,-331.8287 1741.2208,-325.4776 1730.6309,-325.1542 1732.7406,-331.8287"/>
+</g>
+<!-- 20&#45;&gt;23 -->
+<g id="edge59" class="edge">
+<title>20&#45;&gt;23</title>
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+<!-- 20&#45;&gt;25 -->
+<g id="edge62" class="edge">
+<title>20&#45;&gt;25</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1446.1458,-369.2275C1452.4296,-367.6071 1458.8468,-366.1312 1465,-365 1646.4524,-331.6434 1703.7509,-379.9765 1885.3975,-328.4949"/>
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+<!-- 20&#45;&gt;27 -->
+<g id="edge65" class="edge">
+<title>20&#45;&gt;27</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1446.1323,-369.1527C1452.4181,-367.5436 1458.8395,-366.0907 1465,-365 1680.3117,-326.8796 1747.6433,-388.0704 1962.5957,-328.4183"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1963.6122,-331.7681 1972.2811,-325.677 1961.7059,-325.0327 1963.6122,-331.7681"/>
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+<!-- 20&#45;&gt;29 -->
+<g id="edge68" class="edge">
+<title>20&#45;&gt;29</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1446.1227,-369.0978C1452.4099,-367.497 1458.8343,-366.061 1465,-365 1714.1433,-322.1268 1791.4827,-396.1733 2039.6319,-328.3938"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="2040.5931,-331.7594 2049.2899,-325.7082 2038.7178,-325.0153 2040.5931,-331.7594"/>
+</g>
+<!-- 20&#45;&gt;31 -->
+<g id="edge71" class="edge">
+<title>20&#45;&gt;31</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1446.1156,-369.0557C1452.4039,-367.4613 1458.8304,-366.0383 1465,-365 1747.9805,-317.3768 1835.3024,-404.2941 2116.6348,-328.3822"/>
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+</g>
+<!-- 20&#45;&gt;33 -->
+<g id="edge74" class="edge">
+<title>20&#45;&gt;33</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1446.11,-369.0226C1452.3992,-367.4331 1458.8274,-366.0203 1465,-365 1781.7698,-312.6371 1879.0766,-412.3939 2193.4602,-328.4205"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="2194.5668,-331.7469 2203.3018,-325.751 2192.7342,-324.991 2194.5668,-331.7469"/>
+</g>
+<!-- 20&#45;&gt;35 -->
+<g id="edge77" class="edge">
+<title>20&#45;&gt;35</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1446.1056,-368.9957C1452.3954,-367.4103 1458.825,-366.0058 1465,-365 1638.847,-336.6828 2081.9914,-374.4621 2270.4381,-328.3244"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="2271.5042,-331.6638 2280.3059,-325.7663 2269.7476,-324.8878 2271.5042,-331.6638"/>
+</g>
+<!-- 20&#45;&gt;37 -->
+<g id="edge80" class="edge">
+<title>20&#45;&gt;37</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1446.102,-368.9735C1452.3924,-367.3914 1458.8231,-365.9938 1465,-365 1655.7675,-334.3073 2142.3184,-378.4659 2347.4594,-328.3194"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="2348.5003,-331.6655 2357.3093,-325.779 2346.7521,-324.8873 2348.5003,-331.6655"/>
+</g>
+<!-- 20&#45;&gt;39 -->
+<g id="edge83" class="edge">
+<title>20&#45;&gt;39</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1357.9484,-382.5105C1214.2214,-380.5385 759.3079,-371.244 596.6119,-328.7734"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="597.3533,-325.3473 586.7826,-326.0619 595.4918,-332.0952 597.3533,-325.3473"/>
+</g>
+<!-- 20&#45;&gt;41 -->
+<g id="edge86" class="edge">
+<title>20&#45;&gt;41</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1357.6431,-382.1435C1223.1111,-379.1745 820.4056,-367.4578 673.5033,-328.752"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="674.3614,-325.3578 663.7886,-326.041 672.4798,-332.1002 674.3614,-325.3578"/>
+</g>
+<!-- 20&#45;&gt;43 -->
+<g id="edge89" class="edge">
+<title>20&#45;&gt;43</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1357.8722,-381.7037C1233.6689,-377.6939 882.1107,-363.7693 750.6173,-328.792"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="751.3713,-325.368 740.7962,-326.0153 749.4667,-332.104 751.3713,-325.368"/>
+</g>
+<!-- 20&#45;&gt;45 -->
+<g id="edge92" class="edge">
+<title>20&#45;&gt;45</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1357.9579,-381.2239C1244.1455,-376.2737 941.584,-360.7337 825.2647,-328.6511"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="826.1592,-325.266 815.578,-325.8036 824.185,-331.9819 826.1592,-325.266"/>
+</g>
+<!-- 20&#45;&gt;47 -->
+<g id="edge95" class="edge">
+<title>20&#45;&gt;47</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1357.9627,-380.5197C1255.2136,-374.3844 1001.2811,-357.1212 900.172,-328.6444"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="901.1753,-325.2914 890.5909,-325.7623 899.1588,-331.9947 901.1753,-325.2914"/>
+</g>
+<!-- 20&#45;&gt;49 -->
+<g id="edge98" class="edge">
+<title>20&#45;&gt;49</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1357.9734,-379.5733C1267.2119,-372.1775 1061.2389,-353.5988 975.2445,-328.6945"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="976.1967,-325.3255 965.6088,-325.7069 974.1236,-332.0115 976.1967,-325.3255"/>
+</g>
+<!-- 20&#45;&gt;51 -->
+<g id="edge101" class="edge">
+<title>20&#45;&gt;51</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1357.916,-381.0357C1292.1896,-377.0758 1164.9965,-365.4251 1052.6457,-329.0518"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1053.4551,-325.6329 1042.8617,-325.808 1051.2522,-332.2773 1053.4551,-325.6329"/>
+</g>
+<!-- 20&#45;&gt;53 -->
+<g id="edge104" class="edge">
+<title>20&#45;&gt;53</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1357.7292,-378.4166C1304.6789,-372.0279 1213.3568,-358.1734 1129.557,-329.1134"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1130.4991,-325.7338 1119.9043,-325.6853 1128.1564,-332.3302 1130.4991,-325.7338"/>
+</g>
+<!-- 20&#45;&gt;55 -->
+<g id="edge107" class="edge">
+<title>20&#45;&gt;55</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1357.9209,-374.2442C1319.0848,-365.8257 1261.0971,-351.5386 1204.2406,-329.1168"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1205.3424,-325.7874 1194.759,-325.2961 1202.7261,-332.2801 1205.3424,-325.7874"/>
+</g>
+<!-- 20&#45;&gt;57 -->
+<g id="edge110" class="edge">
+<title>20&#45;&gt;57</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1357.9209,-365.0099C1336.167,-355.8579 1309.4366,-344.207 1278.7444,-329.2059"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1280.057,-325.9508 1269.5405,-324.6648 1276.9597,-332.2283 1280.057,-325.9508"/>
+</g>
+<!-- 20&#45;&gt;59 -->
+<g id="edge113" class="edge">
+<title>20&#45;&gt;59</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1381.1818,-364.9656C1371.1814,-356.3025 1358.9767,-345.7298 1347.8438,-336.0857"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1349.8237,-333.1701 1339.9737,-329.2679 1345.2403,-338.461 1349.8237,-333.1701"/>
+</g>
+<!-- 20&#45;&gt;61 -->
+<g id="edge116" class="edge">
+<title>20&#45;&gt;61</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1399.5793,-364.9656C1398.5406,-357.2277 1397.2975,-347.9663 1396.1213,-339.2038"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1399.587,-338.7133 1394.7876,-329.2679 1392.6492,-339.6446 1399.587,-338.7133"/>
+</g>
+<!-- 20&#45;&gt;63 -->
+<g id="edge119" class="edge">
+<title>20&#45;&gt;63</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1418.2188,-364.9656C1425.7829,-356.5548 1434.9657,-346.3441 1443.4315,-336.9306"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1446.2383,-339.0437 1450.3229,-329.2679 1441.0335,-334.3629 1446.2383,-339.0437"/>
+</g>
+<!-- 20&#45;&gt;65 -->
+<g id="edge122" class="edge">
+<title>20&#45;&gt;65</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1437.5698,-364.9268C1457.9461,-354.5186 1483.9674,-341.1339 1507,-329 1507.0953,-328.9498 1507.1908,-328.8995 1507.2864,-328.8491"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1509.2097,-331.7906 1516.3984,-324.0077 1505.9253,-325.6089 1509.2097,-331.7906"/>
+</g>
+<!-- 20&#45;&gt;67 -->
+<g id="edge125" class="edge">
+<title>20&#45;&gt;67</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1446.2612,-370.2319C1495.3398,-355.9932 1569.3046,-334.2645 1582,-329 1582.0952,-328.9605 1582.1905,-328.9209 1582.2858,-328.8811"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1583.6043,-332.1266 1591.25,-324.7922 1580.6992,-325.7579 1583.6043,-332.1266"/>
+</g>
+<!-- 20&#45;&gt;69 -->
+<g id="edge128" class="edge">
+<title>20&#45;&gt;69</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1446.2646,-369.7939C1452.5305,-368.088 1458.911,-366.4374 1465,-365 1549.4978,-345.0528 1575.1508,-357.9565 1657,-329 1657.0972,-328.9656 1657.1944,-328.931 1657.2917,-328.8962"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1658.4822,-332.1916 1666.379,-325.1282 1655.801,-325.7254 1658.4822,-332.1916"/>
+</g>
+<!-- 21&#45;&gt;20 -->
+<g id="edge55" class="edge">
+<title>21&#45;&gt;20</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1307.6498,-957.6736C1094.9219,-951.7118 295.5005,-923.6025 62,-833 49.5696,-828.1768 38,-828.3333 38,-815 38,-815 38,-815 38,-527 38,-459.9531 1094.0255,-399.4079 1347.6969,-385.8313"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1347.9787,-389.3213 1357.7782,-385.2939 1347.6061,-382.3313 1347.9787,-389.3213"/>
+</g>
+<!-- 22 -->
+<g id="node23" class="node">
+<title>22</title>
+<path fill="none" stroke="#d8d356" stroke-width="2" stroke-dasharray="5,2" d="M2086,-252C2086,-252 2012,-252 2012,-252 2006,-252 2000,-246 2000,-240 2000,-240 2000,-228 2000,-228 2000,-222 2006,-216 2012,-216 2012,-216 2086,-216 2086,-216 2092,-216 2098,-222 2098,-228 2098,-228 2098,-240 2098,-240 2098,-246 2092,-252 2086,-252"/>
+<text text-anchor="middle" x="2049" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_rename</text>
+</g>
+<!-- 22&#45;&gt;16 -->
+<g id="edge27" class="edge">
+<title>22&#45;&gt;16</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1999.8027,-218.0522C1996.8385,-217.3032 1993.8882,-216.6107 1991,-216 1845.7959,-185.2953 1671.0775,-170.8944 1583.2449,-165.1783"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1583.4303,-161.6831 1573.2278,-164.5397 1582.9849,-168.6689 1583.4303,-161.6831"/>
+</g>
+<!-- 23&#45;&gt;22 -->
+<g id="edge57" class="edge">
+<title>23&#45;&gt;22</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1877.6268,-291.8819C1880.4264,-290.5049 1883.2469,-289.1878 1886,-288 1905.0515,-279.7803 1951.5794,-264.5332 1990.0694,-252.3315"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1991.1794,-255.6514 1999.6602,-249.3011 1989.0703,-248.9766 1991.1794,-255.6514"/>
+</g>
+<!-- 24 -->
+<g id="node25" class="node">
+<title>24</title>
+<path fill="none" stroke="#d8d356" stroke-width="2" stroke-dasharray="5,2" d="M2202,-252C2202,-252 2128,-252 2128,-252 2122,-252 2116,-246 2116,-240 2116,-240 2116,-228 2116,-228 2116,-222 2122,-216 2128,-216 2128,-216 2202,-216 2202,-216 2208,-216 2214,-222 2214,-228 2214,-228 2214,-240 2214,-240 2214,-246 2208,-252 2202,-252"/>
+<text text-anchor="middle" x="2165" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_rename</text>
+</g>
+<!-- 24&#45;&gt;16 -->
+<g id="edge28" class="edge">
+<title>24&#45;&gt;16</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2115.819,-217.973C2112.8507,-217.2439 2109.8951,-216.5775 2107,-216 1917.6304,-178.228 1688.0849,-166.7606 1583.6454,-163.3716"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1583.4386,-159.8635 1573.3344,-163.0503 1583.2205,-166.8601 1583.4386,-159.8635"/>
+</g>
+<!-- 25&#45;&gt;24 -->
+<g id="edge60" class="edge">
+<title>25&#45;&gt;24</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1954.5359,-291.6599C1957.3546,-290.3295 1960.2043,-289.0839 1963,-288 2021.6256,-265.2712 2041.6012,-269.3206 2105.8796,-252.1937"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="2106.9733,-255.5231 2115.6946,-249.5074 2105.1254,-248.7714 2106.9733,-255.5231"/>
+</g>
+<!-- 26 -->
+<g id="node27" class="node">
+<title>26</title>
+<path fill="none" stroke="#d8d356" stroke-width="2" stroke-dasharray="5,2" d="M2318,-252C2318,-252 2244,-252 2244,-252 2238,-252 2232,-246 2232,-240 2232,-240 2232,-228 2232,-228 2232,-222 2238,-216 2244,-216 2244,-216 2318,-216 2318,-216 2324,-216 2330,-222 2330,-228 2330,-228 2330,-240 2330,-240 2330,-246 2324,-252 2318,-252"/>
+<text text-anchor="middle" x="2281" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_rename</text>
+</g>
+<!-- 26&#45;&gt;16 -->
+<g id="edge29" class="edge">
+<title>26&#45;&gt;16</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2231.8294,-217.9199C2228.8585,-217.2042 2225.8994,-216.5551 2223,-216 2100.7751,-192.5982 1726.7626,-171.9923 1583.5788,-164.7559"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1583.4336,-161.2442 1573.2705,-164.2379 1583.0822,-168.2354 1583.4336,-161.2442"/>
+</g>
+<!-- 27&#45;&gt;26 -->
+<g id="edge63" class="edge">
+<title>27&#45;&gt;26</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2031.904,-291.3137C2034.5964,-290.09 2037.3189,-288.962 2040,-288 2114.9745,-261.1 2140.631,-271.4135 2221.5867,-252.1765"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="2222.8656,-255.4664 2231.7405,-249.6796 2221.194,-248.6689 2222.8656,-255.4664"/>
+</g>
+<!-- 28 -->
+<g id="node29" class="node">
+<title>28</title>
+<path fill="none" stroke="#d8d356" stroke-width="2" stroke-dasharray="5,2" d="M2434,-252C2434,-252 2360,-252 2360,-252 2354,-252 2348,-246 2348,-240 2348,-240 2348,-228 2348,-228 2348,-222 2354,-216 2360,-216 2360,-216 2434,-216 2434,-216 2440,-216 2446,-222 2446,-228 2446,-228 2446,-240 2446,-240 2446,-246 2440,-252 2434,-252"/>
+<text text-anchor="middle" x="2397" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_rename</text>
+</g>
+<!-- 28&#45;&gt;16 -->
+<g id="edge30" class="edge">
+<title>28&#45;&gt;16</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2347.8365,-217.8819C2344.8638,-217.1757 2341.9024,-216.5391 2339,-216 2193.4774,-188.9683 1742.2282,-170.0121 1583.1809,-164.0203"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1583.2575,-160.5208 1573.1337,-163.6444 1582.9958,-167.5159 1583.2575,-160.5208"/>
+</g>
+<!-- 29&#45;&gt;28 -->
+<g id="edge66" class="edge">
+<title>29&#45;&gt;28</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2108.8698,-291.2158C2111.5696,-290.0134 2114.3031,-288.9169 2117,-288 2208.5852,-256.8604 2239.6913,-273.6951 2337.7454,-252.0839"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="2338.7992,-255.4334 2347.7684,-249.7938 2337.24,-248.6092 2338.7992,-255.4334"/>
+</g>
+<!-- 30 -->
+<g id="node31" class="node">
+<title>30</title>
+<path fill="none" stroke="#d8d356" stroke-width="2" stroke-dasharray="5,2" d="M2550,-252C2550,-252 2476,-252 2476,-252 2470,-252 2464,-246 2464,-240 2464,-240 2464,-228 2464,-228 2464,-222 2470,-216 2476,-216 2476,-216 2550,-216 2550,-216 2556,-216 2562,-222 2562,-228 2562,-228 2562,-240 2562,-240 2562,-246 2556,-252 2550,-252"/>
+<text text-anchor="middle" x="2513" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_rename</text>
+</g>
+<!-- 30&#45;&gt;16 -->
+<g id="edge31" class="edge">
+<title>30&#45;&gt;16</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2463.8418,-217.8533C2460.8678,-217.1543 2457.9047,-216.5271 2455,-216 2286.1619,-185.3599 1757.4696,-168.3623 1583.2803,-163.4848"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1583.1482,-159.9799 1573.0549,-163.201 1582.9539,-166.9772 1583.1482,-159.9799"/>
+</g>
+<!-- 31&#45;&gt;30 -->
+<g id="edge69" class="edge">
+<title>31&#45;&gt;30</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2185.8466,-291.1461C2188.5515,-289.9588 2191.2925,-288.8849 2194,-288 2302.2606,-252.616 2338.7061,-276.0738 2453.8832,-252.0187"/>
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+<!-- 32 -->
+<g id="node33" class="node">
+<title>32</title>
+<path fill="none" stroke="#d8d356" stroke-width="2" stroke-dasharray="5,2" d="M2666,-252C2666,-252 2592,-252 2592,-252 2586,-252 2580,-246 2580,-240 2580,-240 2580,-228 2580,-228 2580,-222 2586,-216 2592,-216 2592,-216 2666,-216 2666,-216 2672,-216 2678,-222 2678,-228 2678,-228 2678,-240 2678,-240 2678,-246 2672,-252 2666,-252"/>
+<text text-anchor="middle" x="2629" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_rename</text>
+</g>
+<!-- 32&#45;&gt;16 -->
+<g id="edge32" class="edge">
+<title>32&#45;&gt;16</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2579.8458,-217.831C2576.8708,-217.1376 2573.9063,-216.5178 2571,-216 2378.7575,-181.7522 1772.0767,-166.926 1583.4987,-163.0687"/>
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+</g>
+<!-- 33&#45;&gt;32 -->
+<g id="edge72" class="edge">
+<title>33&#45;&gt;32</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2262.8298,-291.0941C2265.5383,-289.9181 2268.2848,-288.861 2271,-288 2395.8828,-248.3987 2437.6279,-278.4684 2569.7115,-252.0286"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="2570.7197,-255.3941 2579.8001,-249.9355 2569.2976,-248.54 2570.7197,-255.3941"/>
+</g>
+<!-- 34 -->
+<g id="node35" class="node">
+<title>34</title>
+<path fill="none" stroke="#d8d356" stroke-width="2" stroke-dasharray="5,2" d="M2782,-252C2782,-252 2708,-252 2708,-252 2702,-252 2696,-246 2696,-240 2696,-240 2696,-228 2696,-228 2696,-222 2702,-216 2708,-216 2708,-216 2782,-216 2782,-216 2788,-216 2794,-222 2794,-228 2794,-228 2794,-240 2794,-240 2794,-246 2788,-252 2782,-252"/>
+<text text-anchor="middle" x="2745" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_rename</text>
+</g>
+<!-- 34&#45;&gt;16 -->
+<g id="edge33" class="edge">
+<title>34&#45;&gt;16</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2695.849,-217.8131C2692.8731,-217.1242 2689.9077,-216.5103 2687,-216 2471.0833,-178.1092 1784.9136,-165.6259 1583.2511,-162.7266"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1583.2252,-159.2259 1573.1766,-162.5839 1583.126,-166.2252 1583.2252,-159.2259"/>
+</g>
+<!-- 35&#45;&gt;34 -->
+<g id="edge75" class="edge">
+<title>35&#45;&gt;34</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2339.8172,-291.0538C2342.5285,-289.8866 2345.279,-288.8425 2348,-288 2489.6254,-244.1495 2536.5915,-280.9451 2685.8299,-251.9865"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="2686.6948,-255.3827 2695.8099,-249.9823 2685.3166,-248.5197 2686.6948,-255.3827"/>
+</g>
+<!-- 36 -->
+<g id="node37" class="node">
+<title>36</title>
+<path fill="none" stroke="#d8d356" stroke-width="2" stroke-dasharray="5,2" d="M2898,-252C2898,-252 2824,-252 2824,-252 2818,-252 2812,-246 2812,-240 2812,-240 2812,-228 2812,-228 2812,-222 2818,-216 2824,-216 2824,-216 2898,-216 2898,-216 2904,-216 2910,-222 2910,-228 2910,-228 2910,-240 2910,-240 2910,-246 2904,-252 2898,-252"/>
+<text text-anchor="middle" x="2861" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_rename</text>
+</g>
+<!-- 36&#45;&gt;16 -->
+<g id="edge34" class="edge">
+<title>36&#45;&gt;16</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2811.8515,-217.7985C2808.875,-217.1133 2805.9087,-216.5041 2803,-216 2563.4662,-174.4859 1798.0584,-164.4707 1583.4317,-162.4519"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1583.3665,-158.9512 1573.3347,-162.359 1583.302,-165.9509 1583.3665,-158.9512"/>
+</g>
+<!-- 37&#45;&gt;36 -->
+<g id="edge78" class="edge">
+<title>37&#45;&gt;36</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2416.5479,-306.1834C2483.6161,-300.5656 2652.5013,-284.3934 2801.9725,-252.0368"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="2802.7715,-255.4448 2811.7885,-249.8821 2801.2706,-248.6076 2802.7715,-255.4448"/>
+</g>
+<!-- 38 -->
+<g id="node39" class="node">
+<title>38</title>
+<path fill="none" stroke="#d8d356" stroke-width="2" stroke-dasharray="5,2" d="M114,-252C114,-252 40,-252 40,-252 34,-252 28,-246 28,-240 28,-240 28,-228 28,-228 28,-222 34,-216 40,-216 40,-216 114,-216 114,-216 120,-216 126,-222 126,-228 126,-228 126,-240 126,-240 126,-246 120,-252 114,-252"/>
+<text text-anchor="middle" x="77" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_rename</text>
+</g>
+<!-- 38&#45;&gt;16 -->
+<g id="edge35" class="edge">
+<title>38&#45;&gt;16</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M126.1464,-217.7863C129.1234,-217.1042 132.0904,-216.499 135,-216 398.3717,-170.8319 1244.2538,-163.4059 1470.7616,-162.2194"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1470.7799,-165.7194 1480.7621,-162.169 1470.7446,-158.7195 1470.7799,-165.7194"/>
+</g>
+<!-- 39&#45;&gt;38 -->
+<g id="edge81" class="edge">
+<title>39&#45;&gt;38</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M527.2839,-306.2475C459.425,-300.7382 287.8543,-284.7368 136.1711,-252.0648"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="136.7267,-248.6037 126.2101,-249.8886 135.2326,-255.4424 136.7267,-248.6037"/>
+</g>
+<!-- 40 -->
+<g id="node41" class="node">
+<title>40</title>
+<path fill="none" stroke="#d8d356" stroke-width="2" stroke-dasharray="5,2" d="M230,-252C230,-252 156,-252 156,-252 150,-252 144,-246 144,-240 144,-240 144,-228 144,-228 144,-222 150,-216 156,-216 156,-216 230,-216 230,-216 236,-216 242,-222 242,-228 242,-228 242,-240 242,-240 242,-246 236,-252 230,-252"/>
+<text text-anchor="middle" x="193" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_rename</text>
+</g>
+<!-- 40&#45;&gt;16 -->
+<g id="edge36" class="edge">
+<title>40&#45;&gt;16</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M242.1485,-217.7985C245.125,-217.1133 248.0913,-216.5041 251,-216 490.5338,-174.4859 1255.9416,-164.4707 1470.5683,-162.4519"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1470.698,-165.9509 1480.6653,-162.359 1470.6335,-158.9512 1470.698,-165.9509"/>
+</g>
+<!-- 41&#45;&gt;40 -->
+<g id="edge84" class="edge">
+<title>41&#45;&gt;40</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M604.2506,-291.4267C601.1903,-290.1088 598.0747,-288.9313 595,-288 451.0379,-244.3946 403.6157,-281.273 252.3077,-252.0122"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="252.6813,-248.5176 242.189,-249.9876 251.3079,-255.3816 252.6813,-248.5176"/>
+</g>
+<!-- 42 -->
+<g id="node43" class="node">
+<title>42</title>
+<path fill="none" stroke="#d8d356" stroke-width="2" stroke-dasharray="5,2" d="M346,-252C346,-252 272,-252 272,-252 266,-252 260,-246 260,-240 260,-240 260,-228 260,-228 260,-222 266,-216 272,-216 272,-216 346,-216 346,-216 352,-216 358,-222 358,-228 358,-228 358,-240 358,-240 358,-246 352,-252 346,-252"/>
+<text text-anchor="middle" x="309" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_rename</text>
+</g>
+<!-- 42&#45;&gt;16 -->
+<g id="edge37" class="edge">
+<title>42&#45;&gt;16</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M358.151,-217.8131C361.1269,-217.1242 364.0923,-216.5103 367,-216 582.9167,-178.1092 1269.0864,-165.6259 1470.7489,-162.7266"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1470.874,-166.2252 1480.8234,-162.5839 1470.7748,-159.2259 1470.874,-166.2252"/>
+</g>
+<!-- 43&#45;&gt;42 -->
+<g id="edge87" class="edge">
+<title>43&#45;&gt;42</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M681.2375,-291.4693C678.1799,-290.1428 675.0685,-288.9516 672,-288 544.6845,-248.5163 502.4964,-278.8516 368.0411,-251.9777"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="368.7001,-248.54 358.1985,-249.9422 367.2824,-255.3949 368.7001,-248.54"/>
+</g>
+<!-- 44 -->
+<g id="node45" class="node">
+<title>44</title>
+<path fill="none" stroke="#d8d356" stroke-width="2" stroke-dasharray="5,2" d="M462,-252C462,-252 388,-252 388,-252 382,-252 376,-246 376,-240 376,-240 376,-228 376,-228 376,-222 382,-216 388,-216 388,-216 462,-216 462,-216 468,-216 474,-222 474,-228 474,-228 474,-240 474,-240 474,-246 468,-252 462,-252"/>
+<text text-anchor="middle" x="425" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_rename</text>
+</g>
+<!-- 44&#45;&gt;16 -->
+<g id="edge38" class="edge">
+<title>44&#45;&gt;16</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M474.1542,-217.831C477.1292,-217.1376 480.0937,-216.5178 483,-216 675.2425,-181.7522 1281.9233,-166.926 1470.5013,-163.0687"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1470.8157,-166.5632 1480.7428,-162.8616 1470.6741,-159.5646 1470.8157,-166.5632"/>
+</g>
+<!-- 45&#45;&gt;44 -->
+<g id="edge90" class="edge">
+<title>45&#45;&gt;44</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M758.4344,-291.7085C755.3171,-290.2961 752.1363,-289.0207 749,-288 638.658,-252.0911 601.5142,-276.3574 484.2907,-252.0512"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="484.7235,-248.5643 474.2111,-249.8837 483.2518,-255.4079 484.7235,-248.5643"/>
+</g>
+<!-- 46 -->
+<g id="node47" class="node">
+<title>46</title>
+<path fill="none" stroke="#d8d356" stroke-width="2" stroke-dasharray="5,2" d="M578,-252C578,-252 504,-252 504,-252 498,-252 492,-246 492,-240 492,-240 492,-228 492,-228 492,-222 498,-216 504,-216 504,-216 578,-216 578,-216 584,-216 590,-222 590,-228 590,-228 590,-240 590,-240 590,-246 584,-252 578,-252"/>
+<text text-anchor="middle" x="541" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_rename</text>
+</g>
+<!-- 46&#45;&gt;16 -->
+<g id="edge39" class="edge">
+<title>46&#45;&gt;16</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M590.1582,-217.8533C593.1322,-217.1543 596.0953,-216.5271 599,-216 767.8381,-185.3599 1296.5304,-168.3623 1470.7197,-163.4848"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1471.0461,-166.9772 1480.9451,-163.201 1470.8518,-159.9799 1471.0461,-166.9772"/>
+</g>
+<!-- 47&#45;&gt;46 -->
+<g id="edge93" class="edge">
+<title>47&#45;&gt;46</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M833.4086,-291.7862C830.2963,-290.3586 827.1238,-289.0584 824,-288 731.0818,-256.5164 699.5785,-273.8948 600.0759,-252.0413"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="600.7573,-248.607 590.23,-249.801 599.2042,-255.4325 600.7573,-248.607"/>
+</g>
+<!-- 48 -->
+<g id="node49" class="node">
+<title>48</title>
+<path fill="none" stroke="#d8d356" stroke-width="2" stroke-dasharray="5,2" d="M694,-252C694,-252 620,-252 620,-252 614,-252 608,-246 608,-240 608,-240 608,-228 608,-228 608,-222 614,-216 620,-216 620,-216 694,-216 694,-216 700,-216 706,-222 706,-228 706,-228 706,-240 706,-240 706,-246 700,-252 694,-252"/>
+<text text-anchor="middle" x="657" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_rename</text>
+</g>
+<!-- 48&#45;&gt;16 -->
+<g id="edge40" class="edge">
+<title>48&#45;&gt;16</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M706.1635,-217.8819C709.1362,-217.1757 712.0976,-216.5391 715,-216 860.5226,-188.9683 1311.7718,-170.0121 1470.8191,-164.0203"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1471.0042,-167.5159 1480.8663,-163.6444 1470.7425,-160.5208 1471.0042,-167.5159"/>
+</g>
+<!-- 49&#45;&gt;48 -->
+<g id="edge96" class="edge">
+<title>49&#45;&gt;48</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M908.37,-291.8969C905.2653,-290.4478 902.105,-289.1123 899,-288 823.6171,-260.9972 797.8139,-271.4657 716.462,-252.1862"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="716.8046,-248.6666 706.2586,-249.6831 715.1367,-255.465 716.8046,-248.6666"/>
+</g>
+<!-- 50 -->
+<g id="node51" class="node">
+<title>50</title>
+<path fill="none" stroke="#d8d356" stroke-width="2" stroke-dasharray="5,2" d="M810,-252C810,-252 736,-252 736,-252 730,-252 724,-246 724,-240 724,-240 724,-228 724,-228 724,-222 730,-216 736,-216 736,-216 810,-216 810,-216 816,-216 822,-222 822,-228 822,-228 822,-240 822,-240 822,-246 816,-252 810,-252"/>
+<text text-anchor="middle" x="773" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_rename</text>
+</g>
+<!-- 50&#45;&gt;16 -->
+<g id="edge41" class="edge">
+<title>50&#45;&gt;16</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M822.1706,-217.9199C825.1415,-217.2042 828.1006,-216.5551 831,-216 953.2249,-192.5982 1327.2374,-171.9923 1470.4212,-164.7559"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1470.9178,-168.2354 1480.7295,-164.2379 1470.5664,-161.2442 1470.9178,-168.2354"/>
+</g>
+<!-- 51&#45;&gt;50 -->
+<g id="edge99" class="edge">
+<title>51&#45;&gt;50</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M983.0954,-291.8802C980.0666,-290.4705 977.0007,-289.1476 974,-288 915.655,-265.6859 895.9432,-269.301 832.0623,-252.1834"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="832.877,-248.7775 822.3069,-249.5018 831.0216,-255.5272 832.877,-248.7775"/>
+</g>
+<!-- 52 -->
+<g id="node53" class="node">
+<title>52</title>
+<path fill="none" stroke="#d8d356" stroke-width="2" stroke-dasharray="5,2" d="M926,-252C926,-252 852,-252 852,-252 846,-252 840,-246 840,-240 840,-240 840,-228 840,-228 840,-222 846,-216 852,-216 852,-216 926,-216 926,-216 932,-216 938,-222 938,-228 938,-228 938,-240 938,-240 938,-246 932,-252 926,-252"/>
+<text text-anchor="middle" x="889" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_rename</text>
+</g>
+<!-- 52&#45;&gt;16 -->
+<g id="edge42" class="edge">
+<title>52&#45;&gt;16</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M938.181,-217.973C941.1493,-217.2439 944.1049,-216.5775 947,-216 1136.3696,-178.228 1365.9151,-166.7606 1470.3546,-163.3716"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1470.7795,-166.8601 1480.6656,-163.0503 1470.5614,-159.8635 1470.7795,-166.8601"/>
+</g>
+<!-- 53&#45;&gt;52 -->
+<g id="edge102" class="edge">
+<title>53&#45;&gt;52</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1060.4304,-292.3233C1057.2802,-290.791 1054.0962,-289.3195 1051,-288 1032.0175,-279.9105 985.7792,-264.6519 947.5392,-252.4127"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="948.6016,-249.078 938.0109,-249.3723 946.4736,-255.7467 948.6016,-249.078"/>
+</g>
+<!-- 54 -->
+<g id="node55" class="node">
+<title>54</title>
+<path fill="none" stroke="#d8d356" stroke-width="2" stroke-dasharray="5,2" d="M1042,-252C1042,-252 968,-252 968,-252 962,-252 956,-246 956,-240 956,-240 956,-228 956,-228 956,-222 962,-216 968,-216 968,-216 1042,-216 1042,-216 1048,-216 1054,-222 1054,-228 1054,-228 1054,-240 1054,-240 1054,-246 1048,-252 1042,-252"/>
+<text text-anchor="middle" x="1005" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_rename</text>
+</g>
+<!-- 54&#45;&gt;16 -->
+<g id="edge43" class="edge">
+<title>54&#45;&gt;16</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1054.1973,-218.0522C1057.1615,-217.3032 1060.1118,-216.6107 1063,-216 1208.2041,-185.2953 1382.9225,-170.8944 1470.7551,-165.1783"/>
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+</g>
+<!-- 55&#45;&gt;54 -->
+<g id="edge105" class="edge">
+<title>55&#45;&gt;54</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1137.495,-292.8019C1134.3105,-291.144 1131.0985,-289.5129 1128,-288 1105.272,-276.9029 1079.7262,-265.5168 1057.8291,-256.0782"/>
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+</g>
+<!-- 56 -->
+<g id="node57" class="node">
+<title>56</title>
+<path fill="none" stroke="#d8d356" stroke-width="2" stroke-dasharray="5,2" d="M1158,-252C1158,-252 1084,-252 1084,-252 1078,-252 1072,-246 1072,-240 1072,-240 1072,-228 1072,-228 1072,-222 1078,-216 1084,-216 1084,-216 1158,-216 1158,-216 1164,-216 1170,-222 1170,-228 1170,-228 1170,-240 1170,-240 1170,-246 1164,-252 1158,-252"/>
+<text text-anchor="middle" x="1121" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_rename</text>
+</g>
+<!-- 56&#45;&gt;16 -->
+<g id="edge44" class="edge">
+<title>56&#45;&gt;16</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1170.2262,-218.1829C1173.1831,-217.401 1176.1239,-216.6656 1179,-216 1280.699,-192.4631 1401.5359,-176.3021 1470.7474,-168.1477"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1471.4604,-171.5884 1480.9885,-166.9553 1470.6508,-164.6354 1471.4604,-171.5884"/>
+</g>
+<!-- 57&#45;&gt;56 -->
+<g id="edge108" class="edge">
+<title>57&#45;&gt;56</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1212.257,-290.6554C1196.3147,-280.7579 1176.2878,-268.3245 1159.0597,-257.6287"/>
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+</g>
+<!-- 58 -->
+<g id="node59" class="node">
+<title>58</title>
+<path fill="none" stroke="#d8d356" stroke-width="2" stroke-dasharray="5,2" d="M1274,-252C1274,-252 1200,-252 1200,-252 1194,-252 1188,-246 1188,-240 1188,-240 1188,-228 1188,-228 1188,-222 1194,-216 1200,-216 1200,-216 1274,-216 1274,-216 1280,-216 1286,-222 1286,-228 1286,-228 1286,-240 1286,-240 1286,-246 1280,-252 1274,-252"/>
+<text text-anchor="middle" x="1237" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_rename</text>
+</g>
+<!-- 58&#45;&gt;16 -->
+<g id="edge45" class="edge">
+<title>58&#45;&gt;16</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1286.2902,-218.4375C1289.231,-217.5916 1292.1508,-216.7726 1295,-216 1354.6812,-199.8161 1423.7942,-184.1151 1470.9595,-173.8542"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1471.9423,-177.2226 1480.975,-171.6854 1470.4607,-170.3812 1471.9423,-177.2226"/>
+</g>
+<!-- 59&#45;&gt;58 -->
+<g id="edge111" class="edge">
+<title>59&#45;&gt;58</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1293.9941,-287.7476C1284.5349,-278.8272 1273.3984,-268.3251 1263.491,-258.982"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1265.879,-256.4232 1256.2025,-252.1087 1261.0764,-261.5159 1265.879,-256.4232"/>
+</g>
+<!-- 60 -->
+<g id="node61" class="node">
+<title>60</title>
+<path fill="none" stroke="#d8d356" stroke-width="2" stroke-dasharray="5,2" d="M1390,-252C1390,-252 1316,-252 1316,-252 1310,-252 1304,-246 1304,-240 1304,-240 1304,-228 1304,-228 1304,-222 1310,-216 1316,-216 1316,-216 1390,-216 1390,-216 1396,-216 1402,-222 1402,-228 1402,-228 1402,-240 1402,-240 1402,-246 1396,-252 1390,-252"/>
+<text text-anchor="middle" x="1353" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_rename</text>
+</g>
+<!-- 60&#45;&gt;16 -->
+<g id="edge46" class="edge">
+<title>60&#45;&gt;16</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1396.9075,-215.8314C1420.2824,-206.159 1449.2097,-194.1891 1473.8468,-183.9944"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1475.5063,-187.0956 1483.4082,-180.038 1472.8298,-180.6275 1475.5063,-187.0956"/>
+</g>
+<!-- 61&#45;&gt;60 -->
+<g id="edge114" class="edge">
+<title>61&#45;&gt;60</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1381.1363,-287.7476C1376.8329,-279.5269 1371.8261,-269.9627 1367.2392,-261.2004"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1370.2184,-259.3449 1362.4797,-252.1087 1364.0168,-262.5914 1370.2184,-259.3449"/>
+</g>
+<!-- 62 -->
+<g id="node63" class="node">
+<title>62</title>
+<path fill="none" stroke="#d8d356" stroke-width="2" stroke-dasharray="5,2" d="M1506,-252C1506,-252 1432,-252 1432,-252 1426,-252 1420,-246 1420,-240 1420,-240 1420,-228 1420,-228 1420,-222 1426,-216 1432,-216 1432,-216 1506,-216 1506,-216 1512,-216 1518,-222 1518,-228 1518,-228 1518,-240 1518,-240 1518,-246 1512,-252 1506,-252"/>
+<text text-anchor="middle" x="1469" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_rename</text>
+</g>
+<!-- 62&#45;&gt;16 -->
+<g id="edge47" class="edge">
+<title>62&#45;&gt;16</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1483.6358,-215.8314C1490.3161,-207.5386 1498.3568,-197.557 1505.6904,-188.4533"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1508.6194,-190.3965 1512.1671,-180.4133 1503.1681,-186.0052 1508.6194,-190.3965"/>
+</g>
+<!-- 63&#45;&gt;62 -->
+<g id="edge117" class="edge">
+<title>63&#45;&gt;62</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1469,-287.7476C1469,-279.8767 1469,-270.7743 1469,-262.3232"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1472.5001,-262.1086 1469,-252.1087 1465.5001,-262.1087 1472.5001,-262.1086"/>
+</g>
+<!-- 64 -->
+<g id="node65" class="node">
+<title>64</title>
+<path fill="none" stroke="#d8d356" stroke-width="2" stroke-dasharray="5,2" d="M1622,-252C1622,-252 1548,-252 1548,-252 1542,-252 1536,-246 1536,-240 1536,-240 1536,-228 1536,-228 1536,-222 1542,-216 1548,-216 1548,-216 1622,-216 1622,-216 1628,-216 1634,-222 1634,-228 1634,-228 1634,-240 1634,-240 1634,-246 1628,-252 1622,-252"/>
+<text text-anchor="middle" x="1585" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_rename</text>
+</g>
+<!-- 64&#45;&gt;16 -->
+<g id="edge48" class="edge">
+<title>64&#45;&gt;16</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1570.3642,-215.8314C1563.6839,-207.5386 1555.6432,-197.557 1548.3096,-188.4533"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1550.8319,-186.0052 1541.8329,-180.4133 1545.3806,-190.3965 1550.8319,-186.0052"/>
+</g>
+<!-- 65&#45;&gt;64 -->
+<g id="edge120" class="edge">
+<title>65&#45;&gt;64</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1556.1422,-287.7476C1560.603,-279.4394 1565.8005,-269.7591 1570.5457,-260.9211"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1573.6304,-262.5747 1575.2772,-252.1087 1567.4631,-259.2634 1573.6304,-262.5747"/>
+</g>
+<!-- 66 -->
+<g id="node67" class="node">
+<title>66</title>
+<path fill="none" stroke="#d8d356" stroke-width="2" stroke-dasharray="5,2" d="M1738,-252C1738,-252 1664,-252 1664,-252 1658,-252 1652,-246 1652,-240 1652,-240 1652,-228 1652,-228 1652,-222 1658,-216 1664,-216 1664,-216 1738,-216 1738,-216 1744,-216 1750,-222 1750,-228 1750,-228 1750,-240 1750,-240 1750,-246 1744,-252 1738,-252"/>
+<text text-anchor="middle" x="1701" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_rename</text>
+</g>
+<!-- 66&#45;&gt;16 -->
+<g id="edge49" class="edge">
+<title>66&#45;&gt;16</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1657.0925,-215.8314C1633.7176,-206.159 1604.7903,-194.1891 1580.1532,-183.9944"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1581.1702,-180.6275 1570.5918,-180.038 1578.4937,-187.0956 1581.1702,-180.6275"/>
+</g>
+<!-- 67&#45;&gt;66 -->
+<g id="edge123" class="edge">
+<title>67&#45;&gt;66</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1642.563,-287.7476C1652.2617,-278.8272 1663.6801,-268.3251 1673.8384,-258.982"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1676.3205,-261.4544 1681.3114,-252.1087 1671.5818,-256.3022 1676.3205,-261.4544"/>
+</g>
+<!-- 68 -->
+<g id="node69" class="node">
+<title>68</title>
+<path fill="none" stroke="#d8d356" stroke-width="2" stroke-dasharray="5,2" d="M1854,-252C1854,-252 1780,-252 1780,-252 1774,-252 1768,-246 1768,-240 1768,-240 1768,-228 1768,-228 1768,-222 1774,-216 1780,-216 1780,-216 1854,-216 1854,-216 1860,-216 1866,-222 1866,-228 1866,-228 1866,-240 1866,-240 1866,-246 1860,-252 1854,-252"/>
+<text text-anchor="middle" x="1817" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_rename</text>
+</g>
+<!-- 68&#45;&gt;16 -->
+<g id="edge50" class="edge">
+<title>68&#45;&gt;16</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1767.7098,-218.4375C1764.769,-217.5916 1761.8492,-216.7726 1759,-216 1699.3188,-199.8161 1630.2058,-184.1151 1583.0405,-173.8542"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1583.5393,-170.3812 1573.025,-171.6854 1582.0577,-177.2226 1583.5393,-170.3812"/>
+</g>
+<!-- 69&#45;&gt;68 -->
+<g id="edge126" class="edge">
+<title>69&#45;&gt;68</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1723.6036,-291.0331C1739.9166,-281.0714 1760.5843,-268.4506 1778.328,-257.6153"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1780.5912,-260.3342 1787.3017,-252.1354 1776.943,-254.3601 1780.5912,-260.3342"/>
+</g>
+<!-- 70 -->
+<g id="node71" class="node">
+<title>70</title>
+<path fill="none" stroke="#88d856" stroke-width="2" stroke-dasharray="5,2" d="M3129.5,-180C3129.5,-180 3086.5,-180 3086.5,-180 3080.5,-180 3074.5,-174 3074.5,-168 3074.5,-168 3074.5,-156 3074.5,-156 3074.5,-150 3080.5,-144 3086.5,-144 3086.5,-144 3129.5,-144 3129.5,-144 3135.5,-144 3141.5,-150 3141.5,-156 3141.5,-156 3141.5,-168 3141.5,-168 3141.5,-174 3135.5,-180 3129.5,-180"/>
+<text text-anchor="middle" x="3108" y="-159.5" font-family="sans" font-size="10.00" fill="#000000">index_bam</text>
+</g>
+<!-- 70&#45;&gt;0 -->
+<g id="edge7" class="edge">
+<title>70&#45;&gt;0</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3102.2924,-143.7319C3095.6782,-124.5165 3083.4121,-94.0621 3066,-72 3056.8312,-60.3827 3044.6946,-49.7342 3033.2146,-41.02"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3035.1614,-38.1077 3025.0233,-35.0303 3031.0296,-43.7582 3035.1614,-38.1077"/>
+</g>
+<!-- 71 -->
+<g id="node72" class="node">
+<title>71</title>
+<path fill="none" stroke="#d8cb56" stroke-width="2" stroke-dasharray="5,2" d="M3088,-473C3088,-473 3020,-473 3020,-473 3014,-473 3008,-467 3008,-461 3008,-461 3008,-449 3008,-449 3008,-443 3014,-437 3020,-437 3020,-437 3088,-437 3088,-437 3094,-437 3100,-443 3100,-449 3100,-449 3100,-461 3100,-461 3100,-467 3094,-473 3088,-473"/>
+<text text-anchor="middle" x="3054" y="-452.5" font-family="sans" font-size="10.00" fill="#000000">sort_by_position</text>
+</g>
+<!-- 71&#45;&gt;70 -->
+<g id="edge129" class="edge">
+<title>71&#45;&gt;70</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3071.6208,-436.9786C3080.2783,-427.1156 3090.0938,-414.2314 3096,-401 3127.4997,-330.4325 3119.5592,-236.2333 3112.863,-190.0006"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3116.3203,-189.455 3111.34,-180.1037 3109.4017,-190.5197 3116.3203,-189.455"/>
+</g>
+<!-- 102 -->
+<g id="node103" class="node">
+<title>102</title>
+<path fill="none" stroke="#d89556" stroke-width="2" stroke-dasharray="5,2" d="M3074.5,-401C3074.5,-401 3033.5,-401 3033.5,-401 3027.5,-401 3021.5,-395 3021.5,-389 3021.5,-389 3021.5,-377 3021.5,-377 3021.5,-371 3027.5,-365 3033.5,-365 3033.5,-365 3074.5,-365 3074.5,-365 3080.5,-365 3086.5,-371 3086.5,-377 3086.5,-377 3086.5,-389 3086.5,-389 3086.5,-395 3080.5,-401 3074.5,-401"/>
+<text text-anchor="middle" x="3054" y="-380.5" font-family="sans" font-size="10.00" fill="#000000">bamtobed</text>
+</g>
+<!-- 71&#45;&gt;102 -->
+<g id="edge175" class="edge">
+<title>71&#45;&gt;102</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3054,-436.8314C3054,-429.131 3054,-419.9743 3054,-411.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3057.5001,-411.4132 3054,-401.4133 3050.5001,-411.4133 3057.5001,-411.4132"/>
+</g>
+<!-- 72 -->
+<g id="node73" class="node">
+<title>72</title>
+<path fill="none" stroke="#d85656" stroke-width="2" stroke-dasharray="5,2" d="M3086,-545C3086,-545 3018,-545 3018,-545 3012,-545 3006,-539 3006,-533 3006,-533 3006,-521 3006,-521 3006,-515 3012,-509 3018,-509 3018,-509 3086,-509 3086,-509 3092,-509 3098,-515 3098,-521 3098,-521 3098,-533 3098,-533 3098,-539 3092,-545 3086,-545"/>
+<text text-anchor="middle" x="3052" y="-524.5" font-family="sans" font-size="10.00" fill="#000000">convert_to_bam</text>
+</g>
+<!-- 72&#45;&gt;71 -->
+<g id="edge130" class="edge">
+<title>72&#45;&gt;71</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3052.5047,-508.8314C3052.7186,-501.131 3052.9729,-491.9743 3053.2106,-483.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3056.7094,-483.5066 3053.4885,-473.4133 3049.7121,-483.3122 3056.7094,-483.5066"/>
+</g>
+<!-- 73 -->
+<g id="node74" class="node">
+<title>73</title>
+<path fill="none" stroke="#8fd856" stroke-width="2" stroke-dasharray="5,2" d="M3088,-617C3088,-617 3016,-617 3016,-617 3010,-617 3004,-611 3004,-605 3004,-605 3004,-593 3004,-593 3004,-587 3010,-581 3016,-581 3016,-581 3088,-581 3088,-581 3094,-581 3100,-587 3100,-593 3100,-593 3100,-605 3100,-605 3100,-611 3094,-617 3088,-617"/>
+<text text-anchor="middle" x="3052" y="-596.5" font-family="sans" font-size="10.00" fill="#000000">uncollapse_reads</text>
+</g>
+<!-- 73&#45;&gt;72 -->
+<g id="edge131" class="edge">
+<title>73&#45;&gt;72</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3052,-580.8314C3052,-573.131 3052,-563.9743 3052,-555.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3055.5001,-555.4132 3052,-545.4133 3048.5001,-555.4133 3055.5001,-555.4132"/>
+</g>
+<!-- 74 -->
+<g id="node75" class="node">
+<title>74</title>
+<path fill="none" stroke="#56d88a" stroke-width="2" stroke-dasharray="5,2" d="M3089,-689C3089,-689 3015,-689 3015,-689 3009,-689 3003,-683 3003,-677 3003,-677 3003,-665 3003,-665 3003,-659 3009,-653 3015,-653 3015,-653 3089,-653 3089,-653 3095,-653 3101,-659 3101,-665 3101,-665 3101,-677 3101,-677 3101,-683 3095,-689 3089,-689"/>
+<text text-anchor="middle" x="3052" y="-668.5" font-family="sans" font-size="10.00" fill="#000000">remove_inferiors</text>
+</g>
+<!-- 74&#45;&gt;73 -->
+<g id="edge132" class="edge">
+<title>74&#45;&gt;73</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3052,-652.8314C3052,-645.131 3052,-635.9743 3052,-627.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3055.5001,-627.4132 3052,-617.4133 3048.5001,-627.4133 3055.5001,-627.4132"/>
+</g>
+<!-- 75 -->
+<g id="node76" class="node">
+<title>75</title>
+<path fill="none" stroke="#565bd8" stroke-width="2" stroke-dasharray="5,2" d="M3064,-761C3064,-761 3034,-761 3034,-761 3028,-761 3022,-755 3022,-749 3022,-749 3022,-737 3022,-737 3022,-731 3028,-725 3034,-725 3034,-725 3064,-725 3064,-725 3070,-725 3076,-731 3076,-737 3076,-737 3076,-749 3076,-749 3076,-755 3070,-761 3064,-761"/>
+<text text-anchor="middle" x="3049" y="-740.5" font-family="sans" font-size="10.00" fill="#000000">sort_id</text>
+</g>
+<!-- 75&#45;&gt;74 -->
+<g id="edge133" class="edge">
+<title>75&#45;&gt;74</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3049.757,-724.8314C3050.0779,-717.131 3050.4594,-707.9743 3050.816,-699.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3054.3133,-699.5503 3051.2328,-689.4133 3047.3194,-699.2589 3054.3133,-699.5503"/>
+</g>
+<!-- 76&#45;&gt;75 -->
+<g id="edge134" class="edge">
+<title>76&#45;&gt;75</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3049,-796.8314C3049,-789.131 3049,-779.9743 3049,-771.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3052.5001,-771.4132 3049,-761.4133 3045.5001,-771.4133 3052.5001,-771.4132"/>
+</g>
+<!-- 77 -->
+<g id="node78" class="node">
+<title>77</title>
+<path fill="none" stroke="#afd856" stroke-width="2" stroke-dasharray="5,2" d="M3074.5,-905C3074.5,-905 3023.5,-905 3023.5,-905 3017.5,-905 3011.5,-899 3011.5,-893 3011.5,-893 3011.5,-881 3011.5,-881 3011.5,-875 3017.5,-869 3023.5,-869 3023.5,-869 3074.5,-869 3074.5,-869 3080.5,-869 3086.5,-875 3086.5,-881 3086.5,-881 3086.5,-893 3086.5,-893 3086.5,-899 3080.5,-905 3074.5,-905"/>
+<text text-anchor="middle" x="3049" y="-884.5" font-family="sans" font-size="10.00" fill="#000000">cat_mapping</text>
+</g>
+<!-- 77&#45;&gt;76 -->
+<g id="edge136" class="edge">
+<title>77&#45;&gt;76</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3049,-868.8314C3049,-861.131 3049,-851.9743 3049,-843.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3052.5001,-843.4132 3049,-833.4133 3045.5001,-843.4133 3052.5001,-843.4132"/>
+</g>
+<!-- 78&#45;&gt;77 -->
+<g id="edge137" class="edge">
+<title>78&#45;&gt;77</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3348.2271,-950.7407C3285.9642,-937.4776 3163.8638,-911.468 3096.477,-897.1134"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3097.057,-893.6585 3086.5472,-894.9982 3095.5985,-900.5049 3097.057,-893.6585"/>
+</g>
+<!-- 79 -->
+<g id="node80" class="node">
+<title>79</title>
+<path fill="none" stroke="#56d8b9" stroke-width="2" stroke-dasharray="5,2" d="M3458.5,-1049C3458.5,-1049 3315.5,-1049 3315.5,-1049 3309.5,-1049 3303.5,-1043 3303.5,-1037 3303.5,-1037 3303.5,-1025 3303.5,-1025 3303.5,-1019 3309.5,-1013 3315.5,-1013 3315.5,-1013 3458.5,-1013 3458.5,-1013 3464.5,-1013 3470.5,-1019 3470.5,-1025 3470.5,-1025 3470.5,-1037 3470.5,-1037 3470.5,-1043 3464.5,-1049 3458.5,-1049"/>
+<text text-anchor="middle" x="3387" y="-1028.5" font-family="sans" font-size="10.00" fill="#000000">remove_headers_transcriptome</text>
+</g>
+<!-- 79&#45;&gt;78 -->
+<g id="edge139" class="edge">
+<title>79&#45;&gt;78</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3387,-1012.8314C3387,-1005.131 3387,-995.9743 3387,-987.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3390.5001,-987.4132 3387,-977.4133 3383.5001,-987.4133 3390.5001,-987.4132"/>
+</g>
+<!-- 80 -->
+<g id="node81" class="node">
+<title>80</title>
+<path fill="none" stroke="#61d856" stroke-width="2" stroke-dasharray="5,2" d="M3438,-1121C3438,-1121 3336,-1121 3336,-1121 3330,-1121 3324,-1115 3324,-1109 3324,-1109 3324,-1097 3324,-1097 3324,-1091 3330,-1085 3336,-1085 3336,-1085 3438,-1085 3438,-1085 3444,-1085 3450,-1091 3450,-1097 3450,-1097 3450,-1109 3450,-1109 3450,-1115 3444,-1121 3438,-1121"/>
+<text text-anchor="middle" x="3387" y="-1100.5" font-family="sans" font-size="10.00" fill="#000000">filter_nh_transcriptome</text>
+</g>
+<!-- 80&#45;&gt;79 -->
+<g id="edge141" class="edge">
+<title>80&#45;&gt;79</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3387,-1084.8314C3387,-1077.131 3387,-1067.9743 3387,-1059.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3390.5001,-1059.4132 3387,-1049.4133 3383.5001,-1059.4133 3390.5001,-1059.4132"/>
+</g>
+<!-- 81 -->
+<g id="node82" class="node">
+<title>81</title>
+<path fill="none" stroke="#80d856" stroke-width="2" stroke-dasharray="5,2" d="M3449,-1193C3449,-1193 3325,-1193 3325,-1193 3319,-1193 3313,-1187 3313,-1181 3313,-1181 3313,-1169 3313,-1169 3313,-1163 3319,-1157 3325,-1157 3325,-1157 3449,-1157 3449,-1157 3455,-1157 3461,-1163 3461,-1169 3461,-1169 3461,-1181 3461,-1181 3461,-1187 3455,-1193 3449,-1193"/>
+<text text-anchor="middle" x="3387" y="-1172.5" font-family="sans" font-size="10.00" fill="#000000">merge_transcriptome_maps</text>
+</g>
+<!-- 81&#45;&gt;80 -->
+<g id="edge142" class="edge">
+<title>81&#45;&gt;80</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3387,-1156.8314C3387,-1149.131 3387,-1139.9743 3387,-1131.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3390.5001,-1131.4132 3387,-1121.4133 3383.5001,-1131.4133 3390.5001,-1131.4132"/>
+</g>
+<!-- 82&#45;&gt;81 -->
+<g id="edge143" class="edge">
+<title>82&#45;&gt;81</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3483.0684,-1300.7623C3463.8104,-1275.5518 3428.9454,-1229.9103 3406.9338,-1201.0952"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3409.6703,-1198.9117 3400.8185,-1193.0896 3404.1075,-1203.161 3409.6703,-1198.9117"/>
+</g>
+<!-- 83 -->
+<g id="node84" class="node">
+<title>83</title>
+<path fill="none" stroke="#56d0d8" stroke-width="2" stroke-dasharray="5,2" d="M3310.5,-1553C3310.5,-1553 3249.5,-1553 3249.5,-1553 3243.5,-1553 3237.5,-1547 3237.5,-1541 3237.5,-1541 3237.5,-1529 3237.5,-1529 3237.5,-1523 3243.5,-1517 3249.5,-1517 3249.5,-1517 3310.5,-1517 3310.5,-1517 3316.5,-1517 3322.5,-1523 3322.5,-1529 3322.5,-1529 3322.5,-1541 3322.5,-1541 3322.5,-1547 3316.5,-1553 3310.5,-1553"/>
+<text text-anchor="middle" x="3280" y="-1532.5" font-family="sans" font-size="10.00" fill="#000000">fastx_collapser</text>
+</g>
+<!-- 83&#45;&gt;82 -->
+<g id="edge145" class="edge">
+<title>83&#45;&gt;82</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3308.2267,-1516.9229C3322.8001,-1507.0446 3340.5126,-1494.1635 3355,-1481 3368.0022,-1469.1859 3438.411,-1387.4476 3474.9555,-1344.7906"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3477.7299,-1346.9317 3481.5748,-1337.0591 3472.4125,-1342.3791 3477.7299,-1346.9317"/>
+</g>
+<!-- 89 -->
+<g id="node90" class="node">
+<title>89</title>
+<path fill="none" stroke="#56d8d0" stroke-width="2" stroke-dasharray="5,2" d="M3334,-1481C3334,-1481 3226,-1481 3226,-1481 3220,-1481 3214,-1475 3214,-1469 3214,-1469 3214,-1457 3214,-1457 3214,-1451 3220,-1445 3226,-1445 3226,-1445 3334,-1445 3334,-1445 3340,-1445 3346,-1451 3346,-1457 3346,-1457 3346,-1469 3346,-1469 3346,-1475 3340,-1481 3334,-1481"/>
+<text text-anchor="middle" x="3280" y="-1460.5" font-family="sans" font-size="10.00" fill="#000000">filter_fasta_for_oligomap</text>
+</g>
+<!-- 83&#45;&gt;89 -->
+<g id="edge155" class="edge">
+<title>83&#45;&gt;89</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3280,-1516.8314C3280,-1509.131 3280,-1499.9743 3280,-1491.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3283.5001,-1491.4132 3280,-1481.4133 3276.5001,-1491.4133 3283.5001,-1491.4132"/>
+</g>
+<!-- 83&#45;&gt;94 -->
+<g id="edge161" class="edge">
+<title>83&#45;&gt;94</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3237.4646,-1520.689C3206.6021,-1510.3054 3164.3319,-1496.0836 3129.4843,-1484.3592"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3130.462,-1480.9954 3119.8679,-1481.1238 3128.2298,-1487.63 3130.462,-1480.9954"/>
+</g>
+<!-- 84 -->
+<g id="node85" class="node">
+<title>84</title>
+<path fill="none" stroke="#d8a456" stroke-width="2" stroke-dasharray="5,2" d="M3296.5,-1625C3296.5,-1625 3263.5,-1625 3263.5,-1625 3257.5,-1625 3251.5,-1619 3251.5,-1613 3251.5,-1613 3251.5,-1601 3251.5,-1601 3251.5,-1595 3257.5,-1589 3263.5,-1589 3263.5,-1589 3296.5,-1589 3296.5,-1589 3302.5,-1589 3308.5,-1595 3308.5,-1601 3308.5,-1601 3308.5,-1613 3308.5,-1613 3308.5,-1619 3302.5,-1625 3296.5,-1625"/>
+<text text-anchor="middle" x="3280" y="-1604.5" font-family="sans" font-size="10.00" fill="#000000">cutadapt</text>
+</g>
+<!-- 84&#45;&gt;83 -->
+<g id="edge148" class="edge">
+<title>84&#45;&gt;83</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3280,-1588.8314C3280,-1581.131 3280,-1571.9743 3280,-1563.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3283.5001,-1563.4132 3280,-1553.4133 3276.5001,-1563.4133 3283.5001,-1563.4132"/>
+</g>
+<!-- 85 -->
+<g id="node86" class="node">
+<title>85</title>
+<path fill="none" stroke="#9fd856" stroke-width="2" stroke-dasharray="5,2" d="M3313,-1697C3313,-1697 3247,-1697 3247,-1697 3241,-1697 3235,-1691 3235,-1685 3235,-1685 3235,-1673 3235,-1673 3235,-1667 3241,-1661 3247,-1661 3247,-1661 3313,-1661 3313,-1661 3319,-1661 3325,-1667 3325,-1673 3325,-1673 3325,-1685 3325,-1685 3325,-1691 3319,-1697 3313,-1697"/>
+<text text-anchor="middle" x="3280" y="-1676.5" font-family="sans" font-size="10.00" fill="#000000">fasta_formatter</text>
+</g>
+<!-- 85&#45;&gt;84 -->
+<g id="edge149" class="edge">
+<title>85&#45;&gt;84</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3280,-1660.8314C3280,-1653.131 3280,-1643.9743 3280,-1635.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3283.5001,-1635.4132 3280,-1625.4133 3276.5001,-1635.4133 3283.5001,-1635.4132"/>
+</g>
+<!-- 86 -->
+<g id="node87" class="node">
+<title>86</title>
+<path fill="none" stroke="#56a9d8" stroke-width="2" stroke-dasharray="5,2" d="M3312,-1774C3312,-1774 3248,-1774 3248,-1774 3242,-1774 3236,-1768 3236,-1762 3236,-1762 3236,-1745 3236,-1745 3236,-1739 3242,-1733 3248,-1733 3248,-1733 3312,-1733 3312,-1733 3318,-1733 3324,-1739 3324,-1745 3324,-1745 3324,-1762 3324,-1762 3324,-1768 3318,-1774 3312,-1774"/>
+<text text-anchor="middle" x="3280" y="-1762" font-family="sans" font-size="10.00" fill="#000000">start</text>
+<text text-anchor="middle" x="3280" y="-1751" font-family="sans" font-size="10.00" fill="#000000">format: fa</text>
+<text text-anchor="middle" x="3280" y="-1740" font-family="sans" font-size="10.00" fill="#000000">sample: test_lib</text>
+</g>
+<!-- 86&#45;&gt;85 -->
+<g id="edge150" class="edge">
+<title>86&#45;&gt;85</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3280,-1732.7476C3280,-1724.8767 3280,-1715.7743 3280,-1707.3232"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3283.5001,-1707.1086 3280,-1697.1087 3276.5001,-1707.1087 3283.5001,-1707.1086"/>
+</g>
+<!-- 87 -->
+<g id="node88" class="node">
+<title>87</title>
+<path fill="none" stroke="#d6d856" stroke-width="2" stroke-dasharray="5,2" d="M3383.5,-1265C3383.5,-1265 3242.5,-1265 3242.5,-1265 3236.5,-1265 3230.5,-1259 3230.5,-1253 3230.5,-1253 3230.5,-1241 3230.5,-1241 3230.5,-1235 3236.5,-1229 3242.5,-1229 3242.5,-1229 3383.5,-1229 3383.5,-1229 3389.5,-1229 3395.5,-1235 3395.5,-1241 3395.5,-1241 3395.5,-1253 3395.5,-1253 3395.5,-1259 3389.5,-1265 3383.5,-1265"/>
+<text text-anchor="middle" x="3313" y="-1244.5" font-family="sans" font-size="10.00" fill="#000000">oligomap_transcriptome_toSAM</text>
+</g>
+<!-- 87&#45;&gt;81 -->
+<g id="edge144" class="edge">
+<title>87&#45;&gt;81</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3331.6733,-1228.8314C3340.5249,-1220.219 3351.2486,-1209.7851 3360.8895,-1200.4048"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3363.6061,-1202.645 3368.3326,-1193.1628 3358.7246,-1197.6279 3363.6061,-1202.645"/>
+</g>
+<!-- 88&#45;&gt;87 -->
+<g id="edge151" class="edge">
+<title>88&#45;&gt;87</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3258.0391,-1372.862C3246.446,-1363.6621 3234.2598,-1351.3809 3228,-1337 3221.6142,-1322.3296 3220.2953,-1315.0228 3228,-1301 3234.91,-1288.4235 3246.1267,-1278.3606 3258.1782,-1270.4922"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3260.2922,-1273.3047 3267.0514,-1265.1461 3256.6797,-1267.3089 3260.2922,-1273.3047"/>
+</g>
+<!-- 90 -->
+<g id="node91" class="node">
+<title>90</title>
+<path fill="none" stroke="#56d8d8" stroke-width="2" stroke-dasharray="5,2" d="M3377.5,-1337C3377.5,-1337 3248.5,-1337 3248.5,-1337 3242.5,-1337 3236.5,-1331 3236.5,-1325 3236.5,-1325 3236.5,-1313 3236.5,-1313 3236.5,-1307 3242.5,-1301 3248.5,-1301 3248.5,-1301 3377.5,-1301 3377.5,-1301 3383.5,-1301 3389.5,-1307 3389.5,-1313 3389.5,-1313 3389.5,-1325 3389.5,-1325 3389.5,-1331 3383.5,-1337 3377.5,-1337"/>
+<text text-anchor="middle" x="3313" y="-1316.5" font-family="sans" font-size="10.00" fill="#000000">sort_transcriptome_oligomap</text>
+</g>
+<!-- 88&#45;&gt;90 -->
+<g id="edge156" class="edge">
+<title>88&#45;&gt;90</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3292.8132,-1372.8314C3295.7644,-1364.9617 3299.2858,-1355.5712 3302.555,-1346.8533"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3305.8609,-1348.0055 3306.095,-1337.4133 3299.3066,-1345.5476 3305.8609,-1348.0055"/>
+</g>
+<!-- 89&#45;&gt;88 -->
+<g id="edge153" class="edge">
+<title>89&#45;&gt;88</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3281.5141,-1444.8314C3282.1558,-1437.131 3282.9188,-1427.9743 3283.6319,-1419.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3287.1229,-1419.6694 3284.4656,-1409.4133 3280.1471,-1419.088 3287.1229,-1419.6694"/>
+</g>
+<!-- 89&#45;&gt;96 -->
+<g id="edge166" class="edge">
+<title>89&#45;&gt;96</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3224.7687,-1444.9243C3194.4319,-1434.9959 3156.6335,-1422.6255 3124.8945,-1412.2382"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3125.8467,-1408.8672 3115.254,-1409.0831 3123.6694,-1415.52 3125.8467,-1408.8672"/>
+</g>
+<!-- 90&#45;&gt;87 -->
+<g id="edge152" class="edge">
+<title>90&#45;&gt;87</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3313,-1300.8314C3313,-1293.131 3313,-1283.9743 3313,-1275.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3316.5001,-1275.4132 3313,-1265.4133 3309.5001,-1275.4133 3316.5001,-1275.4132"/>
+</g>
+<!-- 91 -->
+<g id="node92" class="node">
+<title>91</title>
+<path fill="none" stroke="#c6d856" stroke-width="2" stroke-dasharray="5,2" d="M3106,-977C3106,-977 2990,-977 2990,-977 2984,-977 2978,-971 2978,-965 2978,-965 2978,-953 2978,-953 2978,-947 2984,-941 2990,-941 2990,-941 3106,-941 3106,-941 3112,-941 3118,-947 3118,-953 3118,-953 3118,-965 3118,-965 3118,-971 3112,-977 3106,-977"/>
+<text text-anchor="middle" x="3048" y="-956.5" font-family="sans" font-size="10.00" fill="#000000">remove_headers_genome</text>
+</g>
+<!-- 91&#45;&gt;77 -->
+<g id="edge138" class="edge">
+<title>91&#45;&gt;77</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3048.2523,-940.8314C3048.3593,-933.131 3048.4865,-923.9743 3048.6053,-915.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3052.1049,-915.4609 3048.7443,-905.4133 3045.1056,-915.3637 3052.1049,-915.4609"/>
+</g>
+<!-- 92 -->
+<g id="node93" class="node">
+<title>92</title>
+<path fill="none" stroke="#d8ac56" stroke-width="2" stroke-dasharray="5,2" d="M3084.5,-1121C3084.5,-1121 3009.5,-1121 3009.5,-1121 3003.5,-1121 2997.5,-1115 2997.5,-1109 2997.5,-1109 2997.5,-1097 2997.5,-1097 2997.5,-1091 3003.5,-1085 3009.5,-1085 3009.5,-1085 3084.5,-1085 3084.5,-1085 3090.5,-1085 3096.5,-1091 3096.5,-1097 3096.5,-1097 3096.5,-1109 3096.5,-1109 3096.5,-1115 3090.5,-1121 3084.5,-1121"/>
+<text text-anchor="middle" x="3047" y="-1100.5" font-family="sans" font-size="10.00" fill="#000000">nh_filter_genome</text>
+</g>
+<!-- 92&#45;&gt;91 -->
+<g id="edge157" class="edge">
+<title>92&#45;&gt;91</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3047.1267,-1084.7623C3047.2972,-1060.201 3047.6024,-1016.2474 3047.8031,-987.3541"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3051.3048,-987.1137 3047.8744,-977.0896 3044.3049,-987.065 3051.3048,-987.1137"/>
+</g>
+<!-- 93 -->
+<g id="node94" class="node">
+<title>93</title>
+<path fill="none" stroke="#567bd8" stroke-width="2" stroke-dasharray="5,2" d="M3095.5,-1193C3095.5,-1193 2998.5,-1193 2998.5,-1193 2992.5,-1193 2986.5,-1187 2986.5,-1181 2986.5,-1181 2986.5,-1169 2986.5,-1169 2986.5,-1163 2992.5,-1157 2998.5,-1157 2998.5,-1157 3095.5,-1157 3095.5,-1157 3101.5,-1157 3107.5,-1163 3107.5,-1169 3107.5,-1169 3107.5,-1181 3107.5,-1181 3107.5,-1187 3101.5,-1193 3095.5,-1193"/>
+<text text-anchor="middle" x="3047" y="-1172.5" font-family="sans" font-size="10.00" fill="#000000">merge_genome_maps</text>
+</g>
+<!-- 93&#45;&gt;92 -->
+<g id="edge158" class="edge">
+<title>93&#45;&gt;92</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3047,-1156.8314C3047,-1149.131 3047,-1139.9743 3047,-1131.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3050.5001,-1131.4132 3047,-1121.4133 3043.5001,-1131.4133 3050.5001,-1131.4132"/>
+</g>
+<!-- 94&#45;&gt;93 -->
+<g id="edge159" class="edge">
+<title>94&#45;&gt;93</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3017.9581,-1444.7975C3002.2267,-1436.359 2986.3922,-1424.6521 2977,-1409 2935.7965,-1340.3348 2931.8348,-1299.9323 2969,-1229 2975.4585,-1216.6735 2986.1505,-1206.6013 2997.5778,-1198.6382"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="2999.4786,-1201.5771 3005.9787,-1193.2105 2995.6798,-1195.6975 2999.4786,-1201.5771"/>
+</g>
+<!-- 95 -->
+<g id="node96" class="node">
+<title>95</title>
+<path fill="none" stroke="#56b9d8" stroke-width="2" stroke-dasharray="5,2" d="M3104,-1265C3104,-1265 2990,-1265 2990,-1265 2984,-1265 2978,-1259 2978,-1253 2978,-1253 2978,-1241 2978,-1241 2978,-1235 2984,-1229 2990,-1229 2990,-1229 3104,-1229 3104,-1229 3110,-1229 3116,-1235 3116,-1241 3116,-1241 3116,-1253 3116,-1253 3116,-1259 3110,-1265 3104,-1265"/>
+<text text-anchor="middle" x="3047" y="-1244.5" font-family="sans" font-size="10.00" fill="#000000">oligomap_genome_toSAM</text>
+</g>
+<!-- 95&#45;&gt;93 -->
+<g id="edge160" class="edge">
+<title>95&#45;&gt;93</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3047,-1228.8314C3047,-1221.131 3047,-1211.9743 3047,-1203.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3050.5001,-1203.4132 3047,-1193.4133 3043.5001,-1203.4133 3050.5001,-1203.4132"/>
+</g>
+<!-- 96&#45;&gt;95 -->
+<g id="edge164" class="edge">
+<title>96&#45;&gt;95</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3034.9572,-1372.8695C3024.188,-1363.5148 3012.7654,-1351.105 3007,-1337 3000.9462,-1322.1895 3001.9856,-1316.1939 3007,-1301 3010.2908,-1291.0288 3016.2116,-1281.3944 3022.5064,-1273.0924"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3025.2672,-1275.2448 3028.8424,-1265.2714 3019.828,-1270.8384 3025.2672,-1275.2448"/>
+</g>
+<!-- 97 -->
+<g id="node98" class="node">
+<title>97</title>
+<path fill="none" stroke="#97d856" stroke-width="2" stroke-dasharray="5,2" d="M3130,-1337C3130,-1337 3028,-1337 3028,-1337 3022,-1337 3016,-1331 3016,-1325 3016,-1325 3016,-1313 3016,-1313 3016,-1307 3022,-1301 3028,-1301 3028,-1301 3130,-1301 3130,-1301 3136,-1301 3142,-1307 3142,-1313 3142,-1313 3142,-1325 3142,-1325 3142,-1331 3136,-1337 3130,-1337"/>
+<text text-anchor="middle" x="3079" y="-1316.5" font-family="sans" font-size="10.00" fill="#000000">sort_genome_oligomap</text>
+</g>
+<!-- 96&#45;&gt;97 -->
+<g id="edge168" class="edge">
+<title>96&#45;&gt;97</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3064.7945,-1372.8314C3066.8489,-1365.0463 3069.296,-1355.7729 3071.5756,-1347.1347"/>
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+<!-- 97&#45;&gt;95 -->
+<g id="edge165" class="edge">
+<title>97&#45;&gt;95</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3070.925,-1300.8314C3067.3898,-1292.8771 3063.164,-1283.369 3059.2544,-1274.5723"/>
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+</g>
+<!-- 98 -->
+<g id="node99" class="node">
+<title>98</title>
+<path fill="none" stroke="#59d856" stroke-width="2" stroke-dasharray="5,2" d="M2834,-108C2834,-108 2778,-108 2778,-108 2772,-108 2766,-102 2766,-96 2766,-96 2766,-84 2766,-84 2766,-78 2772,-72 2778,-72 2778,-72 2834,-72 2834,-72 2840,-72 2846,-78 2846,-84 2846,-84 2846,-96 2846,-96 2846,-102 2840,-108 2834,-108"/>
+<text text-anchor="middle" x="2806" y="-93" font-family="sans" font-size="10.00" fill="#000000">merge_tables</text>
+<text text-anchor="middle" x="2806" y="-82" font-family="sans" font-size="10.00" fill="#000000">mir: miRNA</text>
+</g>
+<!-- 98&#45;&gt;0 -->
+<g id="edge8" class="edge">
+<title>98&#45;&gt;0</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2846.2495,-74.9064C2880.1315,-62.2007 2928.1924,-44.1779 2961.0951,-31.8393"/>
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+</g>
+<!-- 99 -->
+<g id="node100" class="node">
+<title>99</title>
+<path fill="none" stroke="#5692d8" stroke-width="2" stroke-dasharray="5,2" d="M2960.5,-180C2960.5,-180 2909.5,-180 2909.5,-180 2903.5,-180 2897.5,-174 2897.5,-168 2897.5,-168 2897.5,-156 2897.5,-156 2897.5,-150 2903.5,-144 2909.5,-144 2909.5,-144 2960.5,-144 2960.5,-144 2966.5,-144 2972.5,-150 2972.5,-156 2972.5,-156 2972.5,-168 2972.5,-168 2972.5,-174 2966.5,-180 2960.5,-180"/>
+<text text-anchor="middle" x="2935" y="-159.5" font-family="sans" font-size="10.00" fill="#000000">quant_mirna</text>
+</g>
+<!-- 99&#45;&gt;98 -->
+<g id="edge169" class="edge">
+<title>99&#45;&gt;98</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2902.4479,-143.8314C2885.7952,-134.5368 2865.3415,-123.1208 2847.5615,-113.1971"/>
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+</g>
+<!-- 104 -->
+<g id="node105" class="node">
+<title>104</title>
+<path fill="none" stroke="#59d856" stroke-width="2" stroke-dasharray="5,2" d="M3012,-108C3012,-108 2876,-108 2876,-108 2870,-108 2864,-102 2864,-96 2864,-96 2864,-84 2864,-84 2864,-78 2870,-72 2876,-72 2876,-72 3012,-72 3012,-72 3018,-72 3024,-78 3024,-84 3024,-84 3024,-96 3024,-96 3024,-102 3018,-108 3012,-108"/>
+<text text-anchor="middle" x="2944" y="-93" font-family="sans" font-size="10.00" fill="#000000">merge_tables</text>
+<text text-anchor="middle" x="2944" y="-82" font-family="sans" font-size="10.00" fill="#000000">mir: miRNA_primary_transcript</text>
+</g>
+<!-- 99&#45;&gt;104 -->
+<g id="edge177" class="edge">
+<title>99&#45;&gt;104</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2937.2711,-143.8314C2938.2336,-136.131 2939.3782,-126.9743 2940.4479,-118.4166"/>
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+</g>
+<!-- 105 -->
+<g id="node106" class="node">
+<title>105</title>
+<path fill="none" stroke="#59d856" stroke-width="2" stroke-dasharray="5,2" d="M2736,-108C2736,-108 2680,-108 2680,-108 2674,-108 2668,-102 2668,-96 2668,-96 2668,-84 2668,-84 2668,-78 2674,-72 2680,-72 2680,-72 2736,-72 2736,-72 2742,-72 2748,-78 2748,-84 2748,-84 2748,-96 2748,-96 2748,-102 2742,-108 2736,-108"/>
+<text text-anchor="middle" x="2708" y="-93" font-family="sans" font-size="10.00" fill="#000000">merge_tables</text>
+<text text-anchor="middle" x="2708" y="-82" font-family="sans" font-size="10.00" fill="#000000">mir: isomirs</text>
+</g>
+<!-- 99&#45;&gt;105 -->
+<g id="edge179" class="edge">
+<title>99&#45;&gt;105</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2897.2973,-151.2454C2863.1792,-141.3616 2811.3606,-125.9748 2757.7228,-108.1582"/>
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+</g>
+<!-- 100&#45;&gt;99 -->
+<g id="edge171" class="edge">
+<title>100&#45;&gt;99</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2963.411,-215.8314C2959.1683,-207.7925 2954.0879,-198.1666 2949.404,-189.2918"/>
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+</g>
+<!-- 103 -->
+<g id="node104" class="node">
+<title>103</title>
+<path fill="none" stroke="#56d882" stroke-width="2" stroke-dasharray="5,2" d="M2849,-180C2849,-180 2781,-180 2781,-180 2775,-180 2769,-174 2769,-168 2769,-168 2769,-156 2769,-156 2769,-150 2775,-144 2781,-144 2781,-144 2849,-144 2849,-144 2855,-144 2861,-150 2861,-156 2861,-156 2861,-168 2861,-168 2861,-174 2855,-180 2849,-180"/>
+<text text-anchor="middle" x="2815" y="-159.5" font-family="sans" font-size="10.00" fill="#000000">quant_mirna_pri</text>
+</g>
+<!-- 100&#45;&gt;103 -->
+<g id="edge176" class="edge">
+<title>100&#45;&gt;103</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2933.1299,-215.8314C2912.0923,-206.2446 2886.1017,-194.4008 2863.8604,-184.2655"/>
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+</g>
+<!-- 101 -->
+<g id="node102" class="node">
+<title>101</title>
+<path fill="none" stroke="#566bd8" stroke-width="2" stroke-dasharray="5,2" d="M3087.5,-326.5C3087.5,-326.5 3020.5,-326.5 3020.5,-326.5 3014.5,-326.5 3008.5,-320.5 3008.5,-314.5 3008.5,-314.5 3008.5,-302.5 3008.5,-302.5 3008.5,-296.5 3014.5,-290.5 3020.5,-290.5 3020.5,-290.5 3087.5,-290.5 3087.5,-290.5 3093.5,-290.5 3099.5,-296.5 3099.5,-302.5 3099.5,-302.5 3099.5,-314.5 3099.5,-314.5 3099.5,-320.5 3093.5,-326.5 3087.5,-326.5"/>
+<text text-anchor="middle" x="3054" y="-306" font-family="sans" font-size="10.00" fill="#000000">sort_alignments</text>
+</g>
+<!-- 101&#45;&gt;100 -->
+<g id="edge172" class="edge">
+<title>101&#45;&gt;100</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3034.3922,-290.4656C3024.1209,-281.0186 3011.3808,-269.3009 3000.1732,-258.9926"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3002.4376,-256.32 2992.708,-252.1265 2997.6989,-261.4722 3002.4376,-256.32"/>
+</g>
+<!-- 102&#45;&gt;101 -->
+<g id="edge174" class="edge">
+<title>102&#45;&gt;101</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M3054,-364.9656C3054,-356.5178 3054,-346.2542 3054,-336.8064"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="3057.5001,-336.6265 3054,-326.6265 3050.5001,-336.6265 3057.5001,-336.6265"/>
+</g>
+<!-- 103&#45;&gt;98 -->
+<g id="edge170" class="edge">
+<title>103&#45;&gt;98</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2812.7289,-143.8314C2811.7664,-136.131 2810.6218,-126.9743 2809.5521,-118.4166"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="2813.0151,-117.9019 2808.3017,-108.4133 2806.0691,-118.7702 2813.0151,-117.9019"/>
+</g>
+<!-- 103&#45;&gt;104 -->
+<g id="edge178" class="edge">
+<title>103&#45;&gt;104</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2847.5521,-143.8314C2864.2048,-134.5368 2884.6585,-123.1208 2902.4385,-113.1971"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="2904.4321,-116.0927 2911.4583,-108.1628 2901.0205,-109.9803 2904.4321,-116.0927"/>
+</g>
+<!-- 103&#45;&gt;105 -->
+<g id="edge180" class="edge">
+<title>103&#45;&gt;105</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2787.9994,-143.8314C2774.5669,-134.7927 2758.1527,-123.7476 2743.6961,-114.0198"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="2745.2425,-110.8418 2734.992,-108.1628 2741.3346,-116.6494 2745.2425,-110.8418"/>
+</g>
+<!-- 104&#45;&gt;0 -->
+<g id="edge9" class="edge">
+<title>104&#45;&gt;0</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2957.6265,-71.8314C2963.846,-63.5386 2971.3322,-53.557 2978.16,-44.4533"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="2980.99,-46.5133 2984.19,-36.4133 2975.39,-42.3133 2980.99,-46.5133"/>
+</g>
+<!-- 105&#45;&gt;0 -->
+<g id="edge10" class="edge">
+<title>105&#45;&gt;0</title>
+<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M2748.2361,-74.7424C2751.1874,-73.7702 2754.131,-72.8444 2757,-72 2828.2777,-51.0218 2913.4834,-33.7016 2961.103,-24.6991"/>
+<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="2961.773,-28.1346 2970.9579,-22.8537 2960.4845,-21.2542 2961.773,-28.1346"/>
+</g>
+</g>
+</svg>

images/workflow_dag_map.svg

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-<g id="node2" class="node">
-<title>1</title>
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-<!-- 1&#45;&gt;0 -->
-<g id="edge1" class="edge">
-<title>1&#45;&gt;0</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M341,-71.8314C341,-64.131 341,-54.9743 341,-46.4166"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="344.5001,-46.4132 341,-36.4133 337.5001,-46.4133 344.5001,-46.4132"/>
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-<!-- 2 -->
-<g id="node3" class="node">
-<title>2</title>
-<path fill="none" stroke="#56d873" stroke-width="2" stroke-dasharray="5,2" d="M377.5,-180C377.5,-180 304.5,-180 304.5,-180 298.5,-180 292.5,-174 292.5,-168 292.5,-168 292.5,-156 292.5,-156 292.5,-150 298.5,-144 304.5,-144 304.5,-144 377.5,-144 377.5,-144 383.5,-144 389.5,-150 389.5,-156 389.5,-156 389.5,-168 389.5,-168 389.5,-174 383.5,-180 377.5,-180"/>
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-<!-- 2&#45;&gt;1 -->
-<g id="edge2" class="edge">
-<title>2&#45;&gt;1</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M341,-143.8314C341,-136.131 341,-126.9743 341,-118.4166"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="344.5001,-118.4132 341,-108.4133 337.5001,-118.4133 344.5001,-118.4132"/>
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-<!-- 3 -->
-<g id="node4" class="node">
-<title>3</title>
-<path fill="none" stroke="#56b9d8" stroke-width="2" stroke-dasharray="5,2" d="M376.5,-252C376.5,-252 305.5,-252 305.5,-252 299.5,-252 293.5,-246 293.5,-240 293.5,-240 293.5,-228 293.5,-228 293.5,-222 299.5,-216 305.5,-216 305.5,-216 376.5,-216 376.5,-216 382.5,-216 388.5,-222 388.5,-228 388.5,-228 388.5,-240 388.5,-240 388.5,-246 382.5,-252 376.5,-252"/>
-<text text-anchor="middle" x="341" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">convert_to_bam</text>
-</g>
-<!-- 3&#45;&gt;2 -->
-<g id="edge3" class="edge">
-<title>3&#45;&gt;2</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M341,-215.8314C341,-208.131 341,-198.9743 341,-190.4166"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="344.5001,-190.4132 341,-180.4133 337.5001,-190.4133 344.5001,-190.4132"/>
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-<!-- 4 -->
-<g id="node5" class="node">
-<title>4</title>
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-<text text-anchor="middle" x="341" y="-303.5" font-family="sans" font-size="10.00" fill="#000000">uncollapse_reads</text>
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-<!-- 4&#45;&gt;3 -->
-<g id="edge4" class="edge">
-<title>4&#45;&gt;3</title>
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-<g id="node6" class="node">
-<title>5</title>
-<path fill="none" stroke="#56d892" stroke-width="2" stroke-dasharray="5,2" d="M379,-396C379,-396 303,-396 303,-396 297,-396 291,-390 291,-384 291,-384 291,-372 291,-372 291,-366 297,-360 303,-360 303,-360 379,-360 379,-360 385,-360 391,-366 391,-372 391,-372 391,-384 391,-384 391,-390 385,-396 379,-396"/>
-<text text-anchor="middle" x="341" y="-375.5" font-family="sans" font-size="10.00" fill="#000000">remove_inferiors</text>
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-<title>5&#45;&gt;4</title>
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-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="344.5001,-334.4132 341,-324.4133 337.5001,-334.4133 344.5001,-334.4132"/>
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-<g id="node7" class="node">
-<title>6</title>
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-<title>6&#45;&gt;5</title>
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-<g id="node9" class="node">
-<title>8</title>
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-<title>8&#45;&gt;7</title>
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-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="344.5001,-550.4132 341,-540.4133 337.5001,-550.4133 344.5001,-550.4132"/>
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-<g id="node10" class="node">
-<title>9</title>
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-<g id="edge9" class="edge">
-<title>9&#45;&gt;8</title>
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-</g>
-<!-- 10 -->
-<g id="node11" class="node">
-<title>10</title>
-<path fill="none" stroke="#56d8c1" stroke-width="2" stroke-dasharray="5,2" d="M349,-756C349,-756 201,-756 201,-756 195,-756 189,-750 189,-744 189,-744 189,-732 189,-732 189,-726 195,-720 201,-720 201,-720 349,-720 349,-720 355,-720 361,-726 361,-732 361,-732 361,-744 361,-744 361,-750 355,-756 349,-756"/>
-<text text-anchor="middle" x="275" y="-735.5" font-family="sans" font-size="10.00" fill="#000000">remove_headers_transcriptome</text>
-</g>
-<!-- 10&#45;&gt;9 -->
-<g id="edge11" class="edge">
-<title>10&#45;&gt;9</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M275.2523,-719.8314C275.3593,-712.131 275.4865,-702.9743 275.6053,-694.4166"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="279.1049,-694.4609 275.7443,-684.4133 272.1056,-694.3637 279.1049,-694.4609"/>
-</g>
-<!-- 11 -->
-<g id="node12" class="node">
-<title>11</title>
-<path fill="none" stroke="#569ad8" stroke-width="2" stroke-dasharray="5,2" d="M326,-828C326,-828 220,-828 220,-828 214,-828 208,-822 208,-816 208,-816 208,-804 208,-804 208,-798 214,-792 220,-792 220,-792 326,-792 326,-792 332,-792 338,-798 338,-804 338,-804 338,-816 338,-816 338,-822 332,-828 326,-828"/>
-<text text-anchor="middle" x="273" y="-807.5" font-family="sans" font-size="10.00" fill="#000000">filter_nh_transcriptome</text>
-</g>
-<!-- 11&#45;&gt;10 -->
-<g id="edge12" class="edge">
-<title>11&#45;&gt;10</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M273.5047,-791.8314C273.7186,-784.131 273.9729,-774.9743 274.2106,-766.4166"/>
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-<!-- 12 -->
-<g id="node13" class="node">
-<title>12</title>
-<path fill="none" stroke="#8fd856" stroke-width="2" stroke-dasharray="5,2" d="M317,-900C317,-900 187,-900 187,-900 181,-900 175,-894 175,-888 175,-888 175,-876 175,-876 175,-870 181,-864 187,-864 187,-864 317,-864 317,-864 323,-864 329,-870 329,-876 329,-876 329,-888 329,-888 329,-894 323,-900 317,-900"/>
-<text text-anchor="middle" x="252" y="-879.5" font-family="sans" font-size="10.00" fill="#000000">merge_transcriptome_maps</text>
-</g>
-<!-- 12&#45;&gt;11 -->
-<g id="edge13" class="edge">
-<title>12&#45;&gt;11</title>
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-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="268.1894,-838.9933 267.6295,-828.4133 261.4694,-837.0332 268.1894,-838.9933"/>
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-<!-- 13 -->
-<g id="node14" class="node">
-<title>13</title>
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-<text text-anchor="middle" x="93" y="-1095.5" font-family="sans" font-size="10.00" fill="#000000">mapping_transcriptome_segemehl</text>
-</g>
-<!-- 13&#45;&gt;12 -->
-<g id="edge14" class="edge">
-<title>13&#45;&gt;12</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M96.0562,-1079.8994C102.321,-1047.6053 119.327,-979.3819 157,-936 168.0222,-923.3075 182.7958,-912.932 197.4032,-904.7901"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="199.2392,-907.7785 206.442,-900.0086 195.9659,-901.5909 199.2392,-907.7785"/>
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-<!-- 14 -->
-<g id="node15" class="node">
-<title>14</title>
-<path fill="none" stroke="#61d856" stroke-width="2" stroke-dasharray="5,2" d="M361.5,-1260C361.5,-1260 294.5,-1260 294.5,-1260 288.5,-1260 282.5,-1254 282.5,-1248 282.5,-1248 282.5,-1236 282.5,-1236 282.5,-1230 288.5,-1224 294.5,-1224 294.5,-1224 361.5,-1224 361.5,-1224 367.5,-1224 373.5,-1230 373.5,-1236 373.5,-1236 373.5,-1248 373.5,-1248 373.5,-1254 367.5,-1260 361.5,-1260"/>
-<text text-anchor="middle" x="328" y="-1239.5" font-family="sans" font-size="10.00" fill="#000000">fastx_collapser</text>
-</g>
-<!-- 14&#45;&gt;13 -->
-<g id="edge16" class="edge">
-<title>14&#45;&gt;13</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M298.2371,-1223.7623C255.7707,-1197.7404 177.7809,-1149.9508 131.1322,-1121.3661"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="132.8765,-1118.3301 122.5213,-1116.0896 129.2191,-1124.2987 132.8765,-1118.3301"/>
-</g>
-<!-- 20 -->
-<g id="node21" class="node">
-<title>20</title>
-<path fill="none" stroke="#d89c56" stroke-width="2" stroke-dasharray="5,2" d="M385.5,-1188C385.5,-1188 270.5,-1188 270.5,-1188 264.5,-1188 258.5,-1182 258.5,-1176 258.5,-1176 258.5,-1164 258.5,-1164 258.5,-1158 264.5,-1152 270.5,-1152 270.5,-1152 385.5,-1152 385.5,-1152 391.5,-1152 397.5,-1158 397.5,-1164 397.5,-1164 397.5,-1176 397.5,-1176 397.5,-1182 391.5,-1188 385.5,-1188"/>
-<text text-anchor="middle" x="328" y="-1167.5" font-family="sans" font-size="10.00" fill="#000000">filter_fasta_for_oligomap</text>
-</g>
-<!-- 14&#45;&gt;20 -->
-<g id="edge23" class="edge">
-<title>14&#45;&gt;20</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M328,-1223.8314C328,-1216.131 328,-1206.9743 328,-1198.4166"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="331.5001,-1198.4132 328,-1188.4133 324.5001,-1198.4133 331.5001,-1198.4132"/>
-</g>
-<!-- 25 -->
-<g id="node26" class="node">
-<title>25</title>
-<path fill="none" stroke="#56a9d8" stroke-width="2" stroke-dasharray="5,2" d="M626,-1188C626,-1188 492,-1188 492,-1188 486,-1188 480,-1182 480,-1176 480,-1176 480,-1164 480,-1164 480,-1158 486,-1152 492,-1152 492,-1152 626,-1152 626,-1152 632,-1152 638,-1158 638,-1164 638,-1164 638,-1176 638,-1176 638,-1182 632,-1188 626,-1188"/>
-<text text-anchor="middle" x="559" y="-1167.5" font-family="sans" font-size="10.00" fill="#000000">mapping_genome_segemehl</text>
-</g>
-<!-- 14&#45;&gt;25 -->
-<g id="edge29" class="edge">
-<title>14&#45;&gt;25</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M373.6382,-1227.7751C407.1926,-1217.3166 453.3477,-1202.9306 491.2064,-1191.1305"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="492.6366,-1194.3509 501.1421,-1188.0336 490.5535,-1187.6679 492.6366,-1194.3509"/>
-</g>
-<!-- 15 -->
-<g id="node16" class="node">
-<title>15</title>
-<path fill="none" stroke="#d8ac56" stroke-width="2" stroke-dasharray="5,2" d="M345.5,-1332C345.5,-1332 310.5,-1332 310.5,-1332 304.5,-1332 298.5,-1326 298.5,-1320 298.5,-1320 298.5,-1308 298.5,-1308 298.5,-1302 304.5,-1296 310.5,-1296 310.5,-1296 345.5,-1296 345.5,-1296 351.5,-1296 357.5,-1302 357.5,-1308 357.5,-1308 357.5,-1320 357.5,-1320 357.5,-1326 351.5,-1332 345.5,-1332"/>
-<text text-anchor="middle" x="328" y="-1311.5" font-family="sans" font-size="10.00" fill="#000000">cutadapt</text>
-</g>
-<!-- 15&#45;&gt;14 -->
-<g id="edge17" class="edge">
-<title>15&#45;&gt;14</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M328,-1295.8314C328,-1288.131 328,-1278.9743 328,-1270.4166"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="331.5001,-1270.4132 328,-1260.4133 324.5001,-1270.4133 331.5001,-1270.4132"/>
-</g>
-<!-- 16 -->
-<g id="node17" class="node">
-<title>16</title>
-<path fill="none" stroke="#d86656" stroke-width="2" stroke-dasharray="5,2" d="M362.5,-1404C362.5,-1404 293.5,-1404 293.5,-1404 287.5,-1404 281.5,-1398 281.5,-1392 281.5,-1392 281.5,-1380 281.5,-1380 281.5,-1374 287.5,-1368 293.5,-1368 293.5,-1368 362.5,-1368 362.5,-1368 368.5,-1368 374.5,-1374 374.5,-1380 374.5,-1380 374.5,-1392 374.5,-1392 374.5,-1398 368.5,-1404 362.5,-1404"/>
-<text text-anchor="middle" x="328" y="-1383.5" font-family="sans" font-size="10.00" fill="#000000">fasta_formatter</text>
-</g>
-<!-- 16&#45;&gt;15 -->
-<g id="edge18" class="edge">
-<title>16&#45;&gt;15</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M328,-1367.8314C328,-1360.131 328,-1350.9743 328,-1342.4166"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="331.5001,-1342.4132 328,-1332.4133 324.5001,-1342.4133 331.5001,-1342.4132"/>
-</g>
-<!-- 17 -->
-<g id="node18" class="node">
-<title>17</title>
-<path fill="none" stroke="#afd856" stroke-width="2" stroke-dasharray="5,2" d="M385.5,-1481C385.5,-1481 270.5,-1481 270.5,-1481 264.5,-1481 258.5,-1475 258.5,-1469 258.5,-1469 258.5,-1452 258.5,-1452 258.5,-1446 264.5,-1440 270.5,-1440 270.5,-1440 385.5,-1440 385.5,-1440 391.5,-1440 397.5,-1446 397.5,-1452 397.5,-1452 397.5,-1469 397.5,-1469 397.5,-1475 391.5,-1481 385.5,-1481"/>
-<text text-anchor="middle" x="328" y="-1469" font-family="sans" font-size="10.00" fill="#000000">uncompress_zipped_files</text>
-<text text-anchor="middle" x="328" y="-1458" font-family="sans" font-size="10.00" fill="#000000">format: fa</text>
-<text text-anchor="middle" x="328" y="-1447" font-family="sans" font-size="10.00" fill="#000000">sample: test_lib</text>
-</g>
-<!-- 17&#45;&gt;16 -->
-<g id="edge19" class="edge">
-<title>17&#45;&gt;16</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M328,-1439.7476C328,-1431.8767 328,-1422.7743 328,-1414.3232"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="331.5001,-1414.1086 328,-1404.1087 324.5001,-1414.1087 331.5001,-1414.1086"/>
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-<!-- 18 -->
-<g id="node19" class="node">
-<title>18</title>
-<path fill="none" stroke="#56d85b" stroke-width="2" stroke-dasharray="5,2" d="M326,-972C326,-972 178,-972 178,-972 172,-972 166,-966 166,-960 166,-960 166,-948 166,-948 166,-942 172,-936 178,-936 178,-936 326,-936 326,-936 332,-936 338,-942 338,-948 338,-948 338,-960 338,-960 338,-966 332,-972 326,-972"/>
-<text text-anchor="middle" x="252" y="-951.5" font-family="sans" font-size="10.00" fill="#000000">oligomap_transcriptome_toSAM</text>
-</g>
-<!-- 18&#45;&gt;12 -->
-<g id="edge15" class="edge">
-<title>18&#45;&gt;12</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M252,-935.8314C252,-928.131 252,-918.9743 252,-910.4166"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="255.5001,-910.4132 252,-900.4133 248.5001,-910.4133 255.5001,-910.4132"/>
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-<!-- 19 -->
-<g id="node20" class="node">
-<title>19</title>
-<path fill="none" stroke="#d85656" stroke-width="2" stroke-dasharray="5,2" d="M376,-1116C376,-1116 216,-1116 216,-1116 210,-1116 204,-1110 204,-1104 204,-1104 204,-1092 204,-1092 204,-1086 210,-1080 216,-1080 216,-1080 376,-1080 376,-1080 382,-1080 388,-1086 388,-1092 388,-1092 388,-1104 388,-1104 388,-1110 382,-1116 376,-1116"/>
-<text text-anchor="middle" x="296" y="-1095.5" font-family="sans" font-size="10.00" fill="#000000">mapping_transcriptome_oligomap</text>
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-<!-- 19&#45;&gt;18 -->
-<g id="edge20" class="edge">
-<title>19&#45;&gt;18</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M246.4713,-1079.9463C230.6746,-1071.5649 214.9778,-1059.8565 206,-1044 193.896,-1022.6221 208.7881,-997.7098 224.7693,-979.5223"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="227.3609,-981.8751 231.6095,-972.1694 222.2357,-977.1072 227.3609,-981.8751"/>
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-<!-- 21 -->
-<g id="node22" class="node">
-<title>21</title>
-<path fill="none" stroke="#d8cb56" stroke-width="2" stroke-dasharray="5,2" d="M363,-1044C363,-1044 227,-1044 227,-1044 221,-1044 215,-1038 215,-1032 215,-1032 215,-1020 215,-1020 215,-1014 221,-1008 227,-1008 227,-1008 363,-1008 363,-1008 369,-1008 375,-1014 375,-1020 375,-1020 375,-1032 375,-1032 375,-1038 369,-1044 363,-1044"/>
-<text text-anchor="middle" x="295" y="-1023.5" font-family="sans" font-size="10.00" fill="#000000">sort_transcriptome_oligomap</text>
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-<!-- 19&#45;&gt;21 -->
-<g id="edge24" class="edge">
-<title>19&#45;&gt;21</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M295.7477,-1079.8314C295.6407,-1072.131 295.5135,-1062.9743 295.3947,-1054.4166"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="298.8944,-1054.3637 295.2557,-1044.4133 291.8951,-1054.4609 298.8944,-1054.3637"/>
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-<!-- 20&#45;&gt;19 -->
-<g id="edge22" class="edge">
-<title>20&#45;&gt;19</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M319.925,-1151.8314C316.3898,-1143.8771 312.164,-1134.369 308.2544,-1125.5723"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="311.4435,-1124.1299 304.1837,-1116.4133 305.0468,-1126.9729 311.4435,-1124.1299"/>
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-<!-- 27 -->
-<g id="node28" class="node">
-<title>27</title>
-<path fill="none" stroke="#56d8d0" stroke-width="2" stroke-dasharray="5,2" d="M549.5,-1116C549.5,-1116 418.5,-1116 418.5,-1116 412.5,-1116 406.5,-1110 406.5,-1104 406.5,-1104 406.5,-1092 406.5,-1092 406.5,-1086 412.5,-1080 418.5,-1080 418.5,-1080 549.5,-1080 549.5,-1080 555.5,-1080 561.5,-1086 561.5,-1092 561.5,-1092 561.5,-1104 561.5,-1104 561.5,-1110 555.5,-1116 549.5,-1116"/>
-<text text-anchor="middle" x="484" y="-1095.5" font-family="sans" font-size="10.00" fill="#000000">mapping_genome_oligomap</text>
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-<!-- 20&#45;&gt;27 -->
-<g id="edge32" class="edge">
-<title>20&#45;&gt;27</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M367.3654,-1151.8314C388.1367,-1142.2446 413.7983,-1130.4008 435.7581,-1120.2655"/>
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-<!-- 21&#45;&gt;18 -->
-<g id="edge21" class="edge">
-<title>21&#45;&gt;18</title>
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-<!-- 22 -->
-<g id="node23" class="node">
-<title>22</title>
-<path fill="none" stroke="#56d8b1" stroke-width="2" stroke-dasharray="5,2" d="M465.5,-684C465.5,-684 346.5,-684 346.5,-684 340.5,-684 334.5,-678 334.5,-672 334.5,-672 334.5,-660 334.5,-660 334.5,-654 340.5,-648 346.5,-648 346.5,-648 465.5,-648 465.5,-648 471.5,-648 477.5,-654 477.5,-660 477.5,-660 477.5,-672 477.5,-672 477.5,-678 471.5,-684 465.5,-684"/>
-<text text-anchor="middle" x="406" y="-663.5" font-family="sans" font-size="10.00" fill="#000000">remove_headers_genome</text>
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-<!-- 22&#45;&gt;8 -->
-<g id="edge10" class="edge">
-<title>22&#45;&gt;8</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M389.5978,-647.8314C381.9585,-639.3694 372.7317,-629.1489 364.3793,-619.8971"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="366.9221,-617.4906 357.6231,-612.4133 361.7262,-622.1813 366.9221,-617.4906"/>
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-<g id="node24" class="node">
-<title>23</title>
-<path fill="none" stroke="#d87556" stroke-width="2" stroke-dasharray="5,2" d="M455.5,-828C455.5,-828 378.5,-828 378.5,-828 372.5,-828 366.5,-822 366.5,-816 366.5,-816 366.5,-804 366.5,-804 366.5,-798 372.5,-792 378.5,-792 378.5,-792 455.5,-792 455.5,-792 461.5,-792 467.5,-798 467.5,-804 467.5,-804 467.5,-816 467.5,-816 467.5,-822 461.5,-828 455.5,-828"/>
-<text text-anchor="middle" x="417" y="-807.5" font-family="sans" font-size="10.00" fill="#000000">nh_filter_genome</text>
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-<!-- 23&#45;&gt;22 -->
-<g id="edge25" class="edge">
-<title>23&#45;&gt;22</title>
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-<g id="node25" class="node">
-<title>24</title>
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-<text text-anchor="middle" x="446" y="-879.5" font-family="sans" font-size="10.00" fill="#000000">merge_genome_maps</text>
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-<!-- 24&#45;&gt;23 -->
-<g id="edge26" class="edge">
-<title>24&#45;&gt;23</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M438.6821,-863.8314C435.5124,-855.9617 431.73,-846.5712 428.2187,-837.8533"/>
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-<!-- 25&#45;&gt;24 -->
-<g id="edge27" class="edge">
-<title>25&#45;&gt;24</title>
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-<!-- 26 -->
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-<title>10&#45;&gt;19</title>
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-</g>
-<!-- 11 -->
-<g id="node12" class="node">
-<title>11</title>
-<path fill="none" stroke="#d85656" stroke-width="2" stroke-dasharray="5,2" d="M612,-545C612,-545 535,-545 535,-545 529,-545 523,-539 523,-533 523,-533 523,-521 523,-521 523,-515 529,-509 535,-509 535,-509 612,-509 612,-509 618,-509 624,-515 624,-521 624,-521 624,-533 624,-533 624,-539 618,-545 612,-545"/>
-<text text-anchor="middle" x="573.5" y="-524.5" font-family="sans" font-size="10.00" fill="#000000">filter_mir_1_anno</text>
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-<!-- 11&#45;&gt;10 -->
-<g id="edge15" class="edge">
-<title>11&#45;&gt;10</title>
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-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="577.0001,-483.4132 573.5,-473.4133 570.0001,-483.4133 577.0001,-483.4132"/>
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-<!-- 12 -->
-<g id="node13" class="node">
-<title>12</title>
-<path fill="none" stroke="#5682d8" stroke-width="2" stroke-dasharray="5,2" d="M610,-617C610,-617 537,-617 537,-617 531,-617 525,-611 525,-605 525,-605 525,-593 525,-593 525,-587 531,-581 537,-581 537,-581 610,-581 610,-581 616,-581 622,-587 622,-593 622,-593 622,-605 622,-605 622,-611 616,-617 610,-617"/>
-<text text-anchor="middle" x="573.5" y="-596.5" font-family="sans" font-size="10.00" fill="#000000">map_chr_names</text>
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-<!-- 12&#45;&gt;11 -->
-<g id="edge16" class="edge">
-<title>12&#45;&gt;11</title>
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-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="577.0001,-555.4132 573.5,-545.4133 570.0001,-555.4133 577.0001,-555.4132"/>
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-<!-- 13&#45;&gt;12 -->
-<g id="edge17" class="edge">
-<title>13&#45;&gt;12</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M521.9116,-652.8314C530.021,-644.3694 539.8156,-634.1489 548.682,-624.8971"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="551.4618,-627.0549 555.854,-617.4133 546.4079,-622.2115 551.4618,-627.0549"/>
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-<!-- 14&#45;&gt;12 -->
-<g id="edge18" class="edge">
-<title>14&#45;&gt;12</title>
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-</g>
-<!-- 15 -->
-<g id="node16" class="node">
-<title>15</title>
-<path fill="none" stroke="#56d86b" stroke-width="2" stroke-dasharray="5,2" d="M747.5,-108C747.5,-108 685.5,-108 685.5,-108 679.5,-108 673.5,-102 673.5,-96 673.5,-96 673.5,-84 673.5,-84 673.5,-78 679.5,-72 685.5,-72 685.5,-72 747.5,-72 747.5,-72 753.5,-72 759.5,-78 759.5,-84 759.5,-84 759.5,-96 759.5,-96 759.5,-102 753.5,-108 747.5,-108"/>
-<text text-anchor="middle" x="716.5" y="-87.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_final</text>
-</g>
-<!-- 15&#45;&gt;0 -->
-<g id="edge6" class="edge">
-<title>15&#45;&gt;0</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M673.2321,-81.6703C599.1603,-67.4105 449.3253,-38.5653 379.6658,-25.1549"/>
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-</g>
-<!-- 16 -->
-<g id="node17" class="node">
-<title>16</title>
-<path fill="none" stroke="#d86e56" stroke-width="2" stroke-dasharray="5,2" d="M939.5,-180C939.5,-180 865.5,-180 865.5,-180 859.5,-180 853.5,-174 853.5,-168 853.5,-168 853.5,-156 853.5,-156 853.5,-150 859.5,-144 865.5,-144 865.5,-144 939.5,-144 939.5,-144 945.5,-144 951.5,-150 951.5,-156 951.5,-156 951.5,-168 951.5,-168 951.5,-174 945.5,-180 939.5,-180"/>
-<text text-anchor="middle" x="902.5" y="-159.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_concat</text>
-</g>
-<!-- 16&#45;&gt;15 -->
-<g id="edge21" class="edge">
-<title>16&#45;&gt;15</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M855.5643,-143.8314C829.1867,-133.6207 796.1948,-120.8496 768.9662,-110.3095"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="770.1849,-107.0282 759.5958,-106.6822 767.6579,-113.5562 770.1849,-107.0282"/>
-</g>
-<!-- 17 -->
-<g id="node18" class="node">
-<title>17</title>
-<path fill="none" stroke="#56d89a" stroke-width="2" stroke-dasharray="5,2" d="M1245,-252C1245,-252 1166,-252 1166,-252 1160,-252 1154,-246 1154,-240 1154,-240 1154,-228 1154,-228 1154,-222 1160,-216 1166,-216 1166,-216 1245,-216 1245,-216 1251,-216 1257,-222 1257,-228 1257,-228 1257,-240 1257,-240 1257,-246 1251,-252 1245,-252"/>
-<text text-anchor="middle" x="1205.5" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_rename</text>
-</g>
-<!-- 17&#45;&gt;16 -->
-<g id="edge22" class="edge">
-<title>17&#45;&gt;16</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1153.8566,-218.2469C1151.0353,-217.4676 1148.2361,-216.7134 1145.5,-216 1083.0986,-199.7293 1010.8817,-184.0796 961.4936,-173.8551"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="962.1224,-170.4112 951.6217,-171.8207 960.7094,-177.2671 962.1224,-170.4112"/>
-</g>
-<!-- 18 -->
-<g id="node19" class="node">
-<title>18</title>
-<path fill="none" stroke="#d88556" stroke-width="2" stroke-dasharray="5,2" d="M1097.5,-329C1097.5,-329 1059.5,-329 1059.5,-329 1053.5,-329 1047.5,-323 1047.5,-317 1047.5,-317 1047.5,-300 1047.5,-300 1047.5,-294 1053.5,-288 1059.5,-288 1059.5,-288 1097.5,-288 1097.5,-288 1103.5,-288 1109.5,-294 1109.5,-300 1109.5,-300 1109.5,-317 1109.5,-317 1109.5,-323 1103.5,-329 1097.5,-329"/>
-<text text-anchor="middle" x="1078.5" y="-317" font-family="sans" font-size="10.00" fill="#000000">iso_anno</text>
-<text text-anchor="middle" x="1078.5" y="-306" font-family="sans" font-size="10.00" fill="#000000">bp_3p: &#45;1</text>
-<text text-anchor="middle" x="1078.5" y="-295" font-family="sans" font-size="10.00" fill="#000000">bp_5p: &#45;1</text>
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-<!-- 18&#45;&gt;17 -->
-<g id="edge31" class="edge">
-<title>18&#45;&gt;17</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1109.5677,-290.2752C1126.6067,-280.28 1147.9043,-267.7864 1166.1013,-257.1118"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1167.8985,-260.1154 1174.753,-252.0366 1164.3566,-254.0775 1167.8985,-260.1154"/>
-</g>
-<!-- 19&#45;&gt;18 -->
-<g id="edge32" class="edge">
-<title>19&#45;&gt;18</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M876.0691,-367.5085C879.256,-366.6447 882.4177,-365.8025 885.5,-365 950.0665,-348.1901 971.0565,-352.6418 1037.6698,-328.8971"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="1039.1864,-332.0696 1047.3813,-325.3544 1036.7874,-325.4935 1039.1864,-332.0696"/>
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-<!-- 23 -->
-<g id="node24" class="node">
-<title>23</title>
-<path fill="none" stroke="#d88556" stroke-width="2" stroke-dasharray="5,2" d="M1177.5,-329C1177.5,-329 1139.5,-329 1139.5,-329 1133.5,-329 1127.5,-323 1127.5,-317 1127.5,-317 1127.5,-300 1127.5,-300 1127.5,-294 1133.5,-288 1139.5,-288 1139.5,-288 1177.5,-288 1177.5,-288 1183.5,-288 1189.5,-294 1189.5,-300 1189.5,-300 1189.5,-317 1189.5,-317 1189.5,-323 1183.5,-329 1177.5,-329"/>
-<text text-anchor="middle" x="1158.5" y="-317" font-family="sans" font-size="10.00" fill="#000000">iso_anno</text>
-<text text-anchor="middle" x="1158.5" y="-306" font-family="sans" font-size="10.00" fill="#000000">bp_3p: &#45;1</text>
-<text text-anchor="middle" x="1158.5" y="-295" font-family="sans" font-size="10.00" fill="#000000">bp_5p: 0</text>
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-<!-- 19&#45;&gt;23 -->
-<g id="edge38" class="edge">
-<title>19&#45;&gt;23</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M876.0004,-367.2218C879.2046,-366.4301 882.3888,-365.682 885.5,-365 984.7553,-343.2422 1016.8807,-360.2118 1117.8083,-328.6955"/>
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-<!-- 25 -->
-<g id="node26" class="node">
-<title>25</title>
-<path fill="none" stroke="#d88556" stroke-width="2" stroke-dasharray="5,2" d="M1257.5,-329C1257.5,-329 1219.5,-329 1219.5,-329 1213.5,-329 1207.5,-323 1207.5,-317 1207.5,-317 1207.5,-300 1207.5,-300 1207.5,-294 1213.5,-288 1219.5,-288 1219.5,-288 1257.5,-288 1257.5,-288 1263.5,-288 1269.5,-294 1269.5,-300 1269.5,-300 1269.5,-317 1269.5,-317 1269.5,-323 1263.5,-329 1257.5,-329"/>
-<text text-anchor="middle" x="1238.5" y="-317" font-family="sans" font-size="10.00" fill="#000000">iso_anno</text>
-<text text-anchor="middle" x="1238.5" y="-306" font-family="sans" font-size="10.00" fill="#000000">bp_3p: &#45;1</text>
-<text text-anchor="middle" x="1238.5" y="-295" font-family="sans" font-size="10.00" fill="#000000">bp_5p: 1</text>
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-<title>19&#45;&gt;25</title>
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-<!-- 27 -->
-<g id="node28" class="node">
-<title>27</title>
-<path fill="none" stroke="#d88556" stroke-width="2" stroke-dasharray="5,2" d="M625.5,-329C625.5,-329 587.5,-329 587.5,-329 581.5,-329 575.5,-323 575.5,-317 575.5,-317 575.5,-300 575.5,-300 575.5,-294 581.5,-288 587.5,-288 587.5,-288 625.5,-288 625.5,-288 631.5,-288 637.5,-294 637.5,-300 637.5,-300 637.5,-317 637.5,-317 637.5,-323 631.5,-329 625.5,-329"/>
-<text text-anchor="middle" x="606.5" y="-317" font-family="sans" font-size="10.00" fill="#000000">iso_anno</text>
-<text text-anchor="middle" x="606.5" y="-306" font-family="sans" font-size="10.00" fill="#000000">bp_3p: 0</text>
-<text text-anchor="middle" x="606.5" y="-295" font-family="sans" font-size="10.00" fill="#000000">bp_5p: &#45;1</text>
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-<g id="edge44" class="edge">
-<title>19&#45;&gt;27</title>
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-<g id="node30" class="node">
-<title>29</title>
-<path fill="none" stroke="#d88556" stroke-width="2" stroke-dasharray="5,2" d="M703.5,-329C703.5,-329 667.5,-329 667.5,-329 661.5,-329 655.5,-323 655.5,-317 655.5,-317 655.5,-300 655.5,-300 655.5,-294 661.5,-288 667.5,-288 667.5,-288 703.5,-288 703.5,-288 709.5,-288 715.5,-294 715.5,-300 715.5,-300 715.5,-317 715.5,-317 715.5,-323 709.5,-329 703.5,-329"/>
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-<title>19&#45;&gt;29</title>
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-<g id="node32" class="node">
-<title>31</title>
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-<text text-anchor="middle" x="763.5" y="-317" font-family="sans" font-size="10.00" fill="#000000">iso_anno</text>
-<text text-anchor="middle" x="763.5" y="-306" font-family="sans" font-size="10.00" fill="#000000">bp_3p: 0</text>
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-<title>19&#45;&gt;31</title>
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-<g id="node34" class="node">
-<title>33</title>
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-<text text-anchor="middle" x="842.5" y="-317" font-family="sans" font-size="10.00" fill="#000000">iso_anno</text>
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-<title>19&#45;&gt;33</title>
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-<g id="node36" class="node">
-<title>35</title>
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-<title>19&#45;&gt;35</title>
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-<title>37</title>
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-<title>19&#45;&gt;37</title>
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-<title>20&#45;&gt;18</title>
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-<title>20&#45;&gt;25</title>
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-<title>20&#45;&gt;29</title>
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-<title>20&#45;&gt;31</title>
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-<!-- 20&#45;&gt;33 -->
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-<title>20&#45;&gt;33</title>
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-<title>20&#45;&gt;35</title>
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-<!-- 20&#45;&gt;37 -->
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-<title>20&#45;&gt;37</title>
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-<title>21&#45;&gt;20</title>
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-<!-- 22 -->
-<g id="node23" class="node">
-<title>22</title>
-<path fill="none" stroke="#56d89a" stroke-width="2" stroke-dasharray="5,2" d="M1366,-252C1366,-252 1287,-252 1287,-252 1281,-252 1275,-246 1275,-240 1275,-240 1275,-228 1275,-228 1275,-222 1281,-216 1287,-216 1287,-216 1366,-216 1366,-216 1372,-216 1378,-222 1378,-228 1378,-228 1378,-240 1378,-240 1378,-246 1372,-252 1366,-252"/>
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-<g id="edge23" class="edge">
-<title>22&#45;&gt;16</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M1274.9141,-218.0093C1272.0779,-217.2913 1269.2598,-216.6153 1266.5,-216 1160.4136,-192.3475 1034.566,-176.2829 962.0781,-168.1673"/>
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-<title>23&#45;&gt;22</title>
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-<!-- 24 -->
-<g id="node25" class="node">
-<title>24</title>
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-<g id="edge24" class="edge">
-<title>24&#45;&gt;16</title>
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-<!-- 25&#45;&gt;24 -->
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-<title>25&#45;&gt;24</title>
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-<g id="node27" class="node">
-<title>26</title>
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-<text text-anchor="middle" x="479.5" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_rename</text>
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-<!-- 26&#45;&gt;16 -->
-<g id="edge25" class="edge">
-<title>26&#45;&gt;16</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M531.2867,-218.1865C534.393,-217.4037 537.4812,-216.6672 540.5,-216 645.9118,-192.7034 770.8468,-176.5451 842.9651,-168.311"/>
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-<!-- 27&#45;&gt;26 -->
-<g id="edge43" class="edge">
-<title>27&#45;&gt;26</title>
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-<!-- 28 -->
-<g id="node29" class="node">
-<title>28</title>
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-<!-- 28&#45;&gt;16 -->
-<g id="edge26" class="edge">
-<title>28&#45;&gt;16</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M652.0176,-218.5362C655.2202,-217.6562 658.4004,-216.8036 661.5,-216 723.2401,-199.9928 794.6002,-184.3557 843.5551,-174.0633"/>
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-<!-- 29&#45;&gt;28 -->
-<g id="edge46" class="edge">
-<title>29&#45;&gt;28</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M661.8228,-287.7476C651.5454,-278.7398 639.4277,-268.119 628.6898,-258.7076"/>
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-<!-- 30 -->
-<g id="node31" class="node">
-<title>30</title>
-<path fill="none" stroke="#56d89a" stroke-width="2" stroke-dasharray="5,2" d="M761,-252C761,-252 682,-252 682,-252 676,-252 670,-246 670,-240 670,-240 670,-228 670,-228 670,-222 676,-216 682,-216 682,-216 761,-216 761,-216 767,-216 773,-222 773,-228 773,-228 773,-240 773,-240 773,-246 767,-252 761,-252"/>
-<text text-anchor="middle" x="721.5" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_rename</text>
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-<!-- 30&#45;&gt;16 -->
-<g id="edge27" class="edge">
-<title>30&#45;&gt;16</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M767.1739,-215.8314C791.5968,-206.1162 821.8466,-194.0831 847.5484,-183.8592"/>
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-<!-- 31&#45;&gt;30 -->
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-<title>31&#45;&gt;30</title>
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-<!-- 32 -->
-<g id="node33" class="node">
-<title>32</title>
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-<text text-anchor="middle" x="842.5" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">iso_anno_rename</text>
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-<g id="edge28" class="edge">
-<title>32&#45;&gt;16</title>
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-<g id="edge52" class="edge">
-<title>33&#45;&gt;32</title>
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-<g id="node35" class="node">
-<title>34</title>
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-<title>34&#45;&gt;16</title>
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-<title>35&#45;&gt;34</title>
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-<!-- 36 -->
-<g id="node37" class="node">
-<title>36</title>
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-<title>36&#45;&gt;16</title>
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images/workflow_dag_quantify.svg

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-<text text-anchor="middle" x="196" y="-93" font-family="sans" font-size="10.00" fill="#000000">merge_tables</text>
-<text text-anchor="middle" x="196" y="-82" font-family="sans" font-size="10.00" fill="#000000">mir: miRNA_primary_transcript</text>
-</g>
-<!-- 2&#45;&gt;11 -->
-<g id="edge15" class="edge">
-<title>2&#45;&gt;11</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M78.2127,-144.0171C99.1933,-134.3954 125.2185,-122.4603 147.4656,-112.2578"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="149.1123,-115.3532 156.743,-108.0032 146.1943,-108.9904 149.1123,-115.3532"/>
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-<!-- 12 -->
-<g id="node13" class="node">
-<title>12</title>
-<path fill="none" stroke="#56d87b" stroke-width="2" stroke-dasharray="5,2" d="M369.5,-108C369.5,-108 310.5,-108 310.5,-108 304.5,-108 298.5,-102 298.5,-96 298.5,-96 298.5,-84 298.5,-84 298.5,-78 304.5,-72 310.5,-72 310.5,-72 369.5,-72 369.5,-72 375.5,-72 381.5,-78 381.5,-84 381.5,-84 381.5,-96 381.5,-96 381.5,-102 375.5,-108 369.5,-108"/>
-<text text-anchor="middle" x="340" y="-93" font-family="sans" font-size="10.00" fill="#000000">merge_tables</text>
-<text text-anchor="middle" x="340" y="-82" font-family="sans" font-size="10.00" fill="#000000">mir: isomirs</text>
-</g>
-<!-- 2&#45;&gt;12 -->
-<g id="edge19" class="edge">
-<title>2&#45;&gt;12</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M78.101,-146.6731C81.0918,-145.7051 84.0817,-144.8 87,-144 171.9414,-120.714 198.9806,-130.5171 288.662,-107.8291"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="289.624,-111.1955 298.424,-105.2954 287.8654,-104.42 289.624,-111.1955"/>
-</g>
-<!-- 3 -->
-<g id="node4" class="node">
-<title>3</title>
-<path fill="none" stroke="#d8a456" stroke-width="2" stroke-dasharray="5,2" d="M148.5,-252C148.5,-252 79.5,-252 79.5,-252 73.5,-252 67.5,-246 67.5,-240 67.5,-240 67.5,-228 67.5,-228 67.5,-222 73.5,-216 79.5,-216 79.5,-216 148.5,-216 148.5,-216 154.5,-216 160.5,-222 160.5,-228 160.5,-228 160.5,-240 160.5,-240 160.5,-246 154.5,-252 148.5,-252"/>
-<text text-anchor="middle" x="114" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">intersect_mirna</text>
-</g>
-<!-- 3&#45;&gt;2 -->
-<g id="edge8" class="edge">
-<title>3&#45;&gt;2</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M95.0743,-215.8314C86.0143,-207.1337 75.0191,-196.5783 65.1735,-187.1265"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="67.5574,-184.5633 57.9196,-180.1628 62.7096,-189.613 67.5574,-184.5633"/>
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-<!-- 6 -->
-<g id="node7" class="node">
-<title>6</title>
-<path fill="none" stroke="#c6d856" stroke-width="2" stroke-dasharray="5,2" d="M180,-180C180,-180 108,-180 108,-180 102,-180 96,-174 96,-168 96,-168 96,-156 96,-156 96,-150 102,-144 108,-144 108,-144 180,-144 180,-144 186,-144 192,-150 192,-156 192,-156 192,-168 192,-168 192,-174 186,-180 180,-180"/>
-<text text-anchor="middle" x="144" y="-159.5" font-family="sans" font-size="10.00" fill="#000000">quant_mirna_pri</text>
-</g>
-<!-- 3&#45;&gt;6 -->
-<g id="edge11" class="edge">
-<title>3&#45;&gt;6</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M121.5703,-215.8314C124.8493,-207.9617 128.762,-198.5712 132.3945,-189.8533"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="135.7124,-190.9902 136.3278,-180.4133 129.2508,-188.2979 135.7124,-190.9902"/>
-</g>
-<!-- 4 -->
-<g id="node5" class="node">
-<title>4</title>
-<path fill="none" stroke="#56d8c9" stroke-width="2" stroke-dasharray="5,2" d="M149.5,-324C149.5,-324 78.5,-324 78.5,-324 72.5,-324 66.5,-318 66.5,-312 66.5,-312 66.5,-300 66.5,-300 66.5,-294 72.5,-288 78.5,-288 78.5,-288 149.5,-288 149.5,-288 155.5,-288 161.5,-294 161.5,-300 161.5,-300 161.5,-312 161.5,-312 161.5,-318 155.5,-324 149.5,-324"/>
-<text text-anchor="middle" x="114" y="-303.5" font-family="sans" font-size="10.00" fill="#000000">sort_alignments</text>
-</g>
-<!-- 4&#45;&gt;3 -->
-<g id="edge9" class="edge">
-<title>4&#45;&gt;3</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M114,-287.8314C114,-280.131 114,-270.9743 114,-262.4166"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="117.5001,-262.4132 114,-252.4133 110.5001,-262.4133 117.5001,-262.4132"/>
-</g>
-<!-- 5 -->
-<g id="node6" class="node">
-<title>5</title>
-<path fill="none" stroke="#78d856" stroke-width="2" stroke-dasharray="5,2" d="M149.5,-396C149.5,-396 78.5,-396 78.5,-396 72.5,-396 66.5,-390 66.5,-384 66.5,-384 66.5,-372 66.5,-372 66.5,-366 72.5,-360 78.5,-360 78.5,-360 149.5,-360 149.5,-360 155.5,-360 161.5,-366 161.5,-372 161.5,-372 161.5,-384 161.5,-384 161.5,-390 155.5,-396 149.5,-396"/>
-<text text-anchor="middle" x="114" y="-381" font-family="sans" font-size="10.00" fill="#000000">bamtobed</text>
-<text text-anchor="middle" x="114" y="-370" font-family="sans" font-size="10.00" fill="#000000">sample: test_lib</text>
-</g>
-<!-- 5&#45;&gt;4 -->
-<g id="edge10" class="edge">
-<title>5&#45;&gt;4</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M114,-359.8314C114,-352.131 114,-342.9743 114,-334.4166"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="117.5001,-334.4132 114,-324.4133 110.5001,-334.4133 117.5001,-334.4132"/>
-</g>
-<!-- 6&#45;&gt;1 -->
-<g id="edge5" class="edge">
-<title>6&#45;&gt;1</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M120.7845,-143.8314C109.453,-134.9632 95.6536,-124.1637 83.3973,-114.5718"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="85.2402,-111.5697 75.2081,-108.1628 80.926,-117.0822 85.2402,-111.5697"/>
-</g>
-<!-- 6&#45;&gt;11 -->
-<g id="edge16" class="edge">
-<title>6&#45;&gt;11</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M157.1218,-143.8314C163.0499,-135.6232 170.1729,-125.7606 176.6933,-116.7323"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="179.684,-118.5693 182.7015,-108.4133 174.0092,-114.4708 179.684,-118.5693"/>
-</g>
-<!-- 6&#45;&gt;12 -->
-<g id="edge20" class="edge">
-<title>6&#45;&gt;12</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M192.198,-144.2946C221.5518,-133.5116 259.0246,-119.7461 288.8932,-108.7739"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="290.1239,-112.0506 298.3037,-105.317 287.7101,-105.4799 290.1239,-112.0506"/>
-</g>
-<!-- 7 -->
-<g id="node8" class="node">
-<title>7</title>
-<path fill="none" stroke="#56a2d8" stroke-width="2" stroke-dasharray="5,2" d="M276,-180C276,-180 222,-180 222,-180 216,-180 210,-174 210,-168 210,-168 210,-156 210,-156 210,-150 216,-144 222,-144 222,-144 276,-144 276,-144 282,-144 288,-150 288,-156 288,-156 288,-168 288,-168 288,-174 282,-180 276,-180"/>
-<text text-anchor="middle" x="249" y="-159.5" font-family="sans" font-size="10.00" fill="#000000">quant_mirna</text>
-</g>
-<!-- 7&#45;&gt;1 -->
-<g id="edge6" class="edge">
-<title>7&#45;&gt;1</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M209.9807,-147.3266C206.9434,-146.197 203.9227,-145.0776 201,-144 168.5287,-132.028 131.996,-118.7844 103.2318,-108.409"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="104.3862,-105.1047 93.7918,-105.0063 102.0125,-111.69 104.3862,-105.1047"/>
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-<!-- 7&#45;&gt;11 -->
-<g id="edge17" class="edge">
-<title>7&#45;&gt;11</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M235.6259,-143.8314C229.5838,-135.6232 222.3237,-125.7606 215.6779,-116.7323"/>
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-<!-- 7&#45;&gt;12 -->
-<g id="edge21" class="edge">
-<title>7&#45;&gt;12</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M271.9631,-143.8314C283.1715,-134.9632 296.8209,-124.1637 308.9439,-114.5718"/>
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-</g>
-<!-- 8 -->
-<g id="node9" class="node">
-<title>8</title>
-<path fill="none" stroke="#d8a456" stroke-width="2" stroke-dasharray="5,2" d="M312.5,-252C312.5,-252 243.5,-252 243.5,-252 237.5,-252 231.5,-246 231.5,-240 231.5,-240 231.5,-228 231.5,-228 231.5,-222 237.5,-216 243.5,-216 243.5,-216 312.5,-216 312.5,-216 318.5,-216 324.5,-222 324.5,-228 324.5,-228 324.5,-240 324.5,-240 324.5,-246 318.5,-252 312.5,-252"/>
-<text text-anchor="middle" x="278" y="-231.5" font-family="sans" font-size="10.00" fill="#000000">intersect_mirna</text>
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-<!-- 8&#45;&gt;7 -->
-<g id="edge12" class="edge">
-<title>8&#45;&gt;7</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M270.6821,-215.8314C267.5124,-207.9617 263.73,-198.5712 260.2187,-189.8533"/>
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-<!-- 10 -->
-<g id="node11" class="node">
-<title>10</title>
-<path fill="none" stroke="#c6d856" stroke-width="2" stroke-dasharray="5,2" d="M390,-180C390,-180 318,-180 318,-180 312,-180 306,-174 306,-168 306,-168 306,-156 306,-156 306,-150 312,-144 318,-144 318,-144 390,-144 390,-144 396,-144 402,-150 402,-156 402,-156 402,-168 402,-168 402,-174 396,-180 390,-180"/>
-<text text-anchor="middle" x="354" y="-159.5" font-family="sans" font-size="10.00" fill="#000000">quant_mirna_pri</text>
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-<!-- 8&#45;&gt;10 -->
-<g id="edge14" class="edge">
-<title>8&#45;&gt;10</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M297.178,-215.8314C306.3588,-207.1337 317.5006,-196.5783 327.4776,-187.1265"/>
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-<!-- 9 -->
-<g id="node10" class="node">
-<title>9</title>
-<path fill="none" stroke="#56d8c9" stroke-width="2" stroke-dasharray="5,2" d="M319,-324C319,-324 237,-324 237,-324 231,-324 225,-318 225,-312 225,-312 225,-300 225,-300 225,-294 231,-288 237,-288 237,-288 319,-288 319,-288 325,-288 331,-294 331,-300 331,-300 331,-312 331,-312 331,-318 325,-324 319,-324"/>
-<text text-anchor="middle" x="278" y="-309" font-family="sans" font-size="10.00" fill="#000000">sort_alignments</text>
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-<!-- 9&#45;&gt;8 -->
-<g id="edge13" class="edge">
-<title>9&#45;&gt;8</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M278,-287.8314C278,-280.131 278,-270.9743 278,-262.4166"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="281.5001,-262.4132 278,-252.4133 274.5001,-262.4133 281.5001,-262.4132"/>
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-<!-- 10&#45;&gt;1 -->
-<g id="edge7" class="edge">
-<title>10&#45;&gt;1</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M305.916,-146.3603C302.9096,-145.5239 299.9198,-144.729 297,-144 214.9089,-123.5033 189.4924,-130.1421 103.257,-107.8279"/>
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-<!-- 10&#45;&gt;11 -->
-<g id="edge18" class="edge">
-<title>10&#45;&gt;11</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M314.1299,-143.8314C293.0923,-134.2446 267.1017,-122.4008 244.8604,-112.2655"/>
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-<!-- 10&#45;&gt;12 -->
-<g id="edge22" class="edge">
-<title>10&#45;&gt;12</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M350.4672,-143.8314C348.9699,-136.131 347.1895,-126.9743 345.5255,-118.4166"/>
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-<!-- 11&#45;&gt;0 -->
-<g id="edge2" class="edge">
-<title>11&#45;&gt;0</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M196,-71.8314C196,-64.131 196,-54.9743 196,-46.4166"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="199.5001,-46.4132 196,-36.4133 192.5001,-46.4133 199.5001,-46.4132"/>
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-<!-- 12&#45;&gt;0 -->
-<g id="edge3" class="edge">
-<title>12&#45;&gt;0</title>
-<path fill="none" stroke="#c0c0c0" stroke-width="2" d="M303.6627,-71.8314C281.7917,-60.8959 254.0472,-47.0236 232.2008,-36.1004"/>
-<polygon fill="#c0c0c0" stroke="#c0c0c0" stroke-width="2" points="233.743,-32.9584 223.2334,-31.6167 230.6124,-39.2194 233.743,-32.9584"/>
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-</g>
-</svg>

test/test_rule_graph.sh

@@ -24,4 +24,4 @@ snakemake \
     --printshellcmds \
     --dryrun \
     --verbose \
-    | dot -Tsvg > "../images/rule_graph_.svg"
+    | dot -Tsvg > "../images/rule_graph.svg"